Adam Grant is a New York Times bestselling author who writes about leadership, creativity, and success. In his book Originals, Grant addresses the challenge of improving the world, but from the perspective of becoming original: choosing to champion novel ideas and values that go against the grain, battle conformity, and buck outdated traditions. How can we originate new ideas, policies, and practices without risking it all? Facebook COO Sheryl Sandberg moderates this thought-provoking conversation and answers these questions with author Adam Grant. Recorded on February 23, 2016.

In an age of sophisticated healthcare technologies and research tools, the doctors you see or hospitals you visit are only a small part of what determines your health. Through extensive research and data analysis, one doctor has found that your zip code may matter more to your well-being than your genetic code. Join us for a conversation about how data helped Dr. Anthony Iton identify this problem—and the role technology can play in solving it. This conversation was moderated by P2Health Ventures co-founder Vanessa Mason. Recorded on August 24, 2017.

Could the key to colonizing space be asteroids? Planetary Resources is developing technology that could enable humans to fly spacecraft to asteroids to procure valuable minerals and other resources that could allow us to go further into space than ever before. Join us as Planetary Resources CEO Chris Lewicki sits down with former Museum CEO John Hollar. Recorded on March 9, 2017.

For Silicon Valley entrepreneurs, “the next billion” often conjures up visions of creating the next “unicorn” company, with a private valuation that tops $1 billion. Technology innovation and economic valuation often go hand in hand. But what about social impact? A growing number of innovators and entrepreneurs are focused on the next billion people who are digitally excluded, many of whom live in extreme poverty, globally and locally. How are entrepreneurs changing the lives of the next billion, one by one? How is technology being used as a force for democratization of access and opportunity? Is there a way to dismantle the false choice between purpose and profit? Join us for a fascinating fireside chat between Julie Hanna, Kiva executive chairman and Presidential Ambassador for Global Entrepreneurship, and Exponential Center Executive Director Marguerite Gong Hancock. Recorded on November 16, 2016.

While tech companies and venture capitalists today are actively starting to support rising female stars, women entrepreneurs often are unheralded. In the past two years, the percentage of female founders raising Series A capital jumped from 10 percent to 14 percent in 2015, but they are still too rare. What can we learn from two successful entrepreneurs who have forged their own paths for innovation and impact? Venture capitalist and partner at Draper Fisher Jurvetson Heidi Roizen and Cloudflare cofounder and Chief Operating Officer Michelle Zatlyn sit down with the Exponential Center Executive Director Marguerite Gong Hancock to discuss“a-ha” moments from the earliest days of their startups, highs and lows in the life of an entrepreneur, and words of advice for innovators. Recorded on September 22, 2016.

Engineers and scientists are not the only ones interested in the potential of artificial intelligence. AI experts are joining leaders in education, medicine, public health, sustainability, housing, and other fields to address long-standing societal challenges. In collaboration with the Partnership on Artificial Intelligence, CHM Live presents a conversation with Facebook Director of AI Research Yann LeCun, Google Principal Scientist Greg Corrado, and Microsoft Technical Fellow and Director of Microsoft Research Labs Eric Horvitz. The conversation was moderated by Museum Historian John Markoff. Recorded on September 28, 2017. Recorded on September 28, 2017.

Artificial Intelligence could improve our ability to communicate, solve problems, and understand the world around us. How do designers, engineers, and technologists build systems that help us work with machines? As part of a series produced in collaboration with the Partnership on Artificial Intelligence, please join us for a conversation with Apple’s Tom Gruber, AAAI President Subbarao Kambhampati, and IBM Distinguished Research Scientist Francesca Rossi. The conversation was moderated by Museum Historian John Markoff. Recorded on September 13, 2017.

Social-coding site GitHub supports over 20 million users—including Google and NASA—who use the online platform to collaborate, build, and store software. Join us as GitHub CEO and cofounder Chris Wanstrath discusses the fascinating story of the company’s growth, the most amazing projects built on the platform, and his vision for the future of software. Wanstrath sits down with Fortune Senior Writer Michal Lev-Ram. Recorded January 17, 2017.

Mary Lou Jepsen has led Facebook’s virtual reality efforts, advised Google’s Sergey Brin, and invented $100 laptops. Now she is turning her consumer electronics experience to the task of curing disease. Join us as Mary Lou Jepsen discusses her Silicon Valley history, her company on the cutting edge of tech and medicine, and her vision for the future of body imaging and healthcare. She sits down with former Computer History Museum CEO John Hollar. Recorded May 4, 2017.

Tony Fadell was hired as a contractor to design the first iPod. It was an auspicious beginning—he would go on to lead the hardware development of the first iPhone. He then left Apple to start Nest, a company that designed a connected thermostat. Google bought Nest for $3.2 billion in 2014. In a conversation with Computer History Museum historian John Markoff, Tony Fadell explores how mobile and internet computing has changed the world in the past decade and what might happen in the next one. Recorded on May 10, 2017.