In this episode of Revolution Health Radio, Chris welcomes psychiatrist Dr. Matt Bernstein to explore the emerging field of metabolic psychiatry, the science linking brain energy metabolism to mental health. They discuss how conditions like depression, bipolar disorder, schizophrenia, and anxiety often share a root cause in impaired brain energy production, and how ketogenic therapy can restore balance and improve outcomes where traditional treatments fall short. Chris and Dr. Bernstein also unpack the latest research, the mechanisms behind ketones’ impact on the brain, and practical considerations for adults, teens, and families exploring this approach.

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In this episode of Revolution Health Radio, Chris explores natural solutions for one of today’s most pressing challenges: chronic stress, anxiety, and poor sleep. He shares his top five nutrients for restoring calm and focus (saffron, L-theanine, lemon balm, holy basil, and ashwagandha), revealing how each supports the brain and body’s ability to relax, recharge, and build resilience. Drawing from both scientific research and clinical experience, Chris explains how these compounds balance neurotransmitters, reduce cortisol, and improve mood and sleep quality without sedation or dependence. Listeners will learn practical strategies for combining these nutrients safely and effectively to achieve steady energy, emotional balance, and deep, restorative rest. This episode offers a roadmap to move from wired and tired to calm and clear, using evidence-based tools rooted in both modern science and ancient wisdom.

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In this episode of Revolution Health Radio, Chris welcomes board-certified periodontist Dr. William Levine to discuss the overlooked role of gum health in systemic disease. They unpack how oral bacteria and chronic inflammation contribute to conditions like heart disease, dementia, autoimmune disorders, and pregnancy complications, and why periodontal health is as critical as diet and lifestyle in preventing chronic illness. Dr. Levine shares how to recognize early signs of gum disease, the latest approaches to treatment and prevention, and the importance of personalized care. The discussion highlights emerging technologies including laser therapy, PRP, photobiomodulation, and PEMF, offering a glimpse into the future of dentistry and frequency medicine. Listeners will come away with a deeper understanding of how maintaining oral health supports whole-body wellness and what promising innovations lie ahead.

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In this episode of Revolution Health Radio, we dive deep into the topic of beauty from within, exploring why radiant skin, hair, and nails truly start from the inside. Chris discusses how internal factors such as gut function, nutrient status, inflammation, blood sugar regulation, hormonal balance, and stress management are foundational to external beauty. He explains the science behind the gut-brain-skin axis, the role of inflammation and leaky gut in skin health, and how stress impacts our appearance. He also highlights six key nutrients that can significantly enhance skin hydration, elasticity, and overall appearance, and shares practical insights into incorporating these science-backed nutrients into your diet or supplementation routine, empowering you to support your natural beauty from the inside out.

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In this episode of Revolution Health Radio, Chris Kresser welcomes environmental wellness expert Michael Rubino for an in-depth conversation on the hidden health risks of indoor air pollution. They delve into why mold-related illness is more common than most people realize, how traditional mold testing methods often fail, and why household dust holds the key to understanding environmental exposure. Michael explains the concept of “clean breathing,” the impact of modern home construction on air quality, and how to assess your indoor environment using practical DIY tools. The discussion also covers overlooked threats like formaldehyde, VOCs, radon, and microplastics, as well as actionable strategies for remediation and improving ventilation. Finally, Michael offers essential advice for vetting professionals, avoiding costly missteps, and creating a healthier home environment for long-term well-being.

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In this episode of Revolution Health Radio, Chris Kresser welcomes food scientist and advocate for regenerative agriculture Dr. Frederic Leroy to discuss his groundbreaking work on the Nourishment Table, a new framework for assessing dietary adequacy. They explore why conventional dietary guidelines fail, how nutrient density and food processing deeply influence human health, and the evolutionary importance of animal-source foods in achieving optimal nutrition. Dr. Leroy highlights the limitations of popular nutritional models, sheds light on overlooked factors like bioavailability and organ meats, and addresses confusion surrounding plant-based diets and processed foods. Their conversation also covers practical tips for implementing this approach in everyday life and insights into navigating complex food policy and nutritional science debates.

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In this episode of Revolution Health Radio, Chris Kresser welcomes entrepreneur and strategist Seth Spears for a wide-ranging conversation on health, resilience, and building businesses with purpose. They explore the origins of Seth’s wellness-focused companies, including Wellnesse and Rewild Gear, and how they challenge conventional thinking in personal care and outdoor lifestyle. Seth shares insights into the philosophy behind creating high-quality, mission-driven products and discusses the often-overlooked importance of oral health, environmental sustainability, and consumer awareness. The conversation also delves into the mental and physical health benefits of reconnecting with nature, raising resilient kids in a tech-saturated world, and embracing voluntary discomfort as a path to personal growth.

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In this episode of Revolution Health Radio, Chris welcomes renowned neurologist Dr. Dale Bredesen back to the show for an insightful conversation about protecting and enhancing cognitive health throughout your lifetime. They discuss groundbreaking advances in Alzheimer's prevention and early detection, explore the latest diagnostic tools and assessment techniques, and review compelling evidence from recent clinical trials. Dr. Bredesen provides actionable advice on essential lifestyle strategies—including diet, exercise, and sleep—that significantly impact brain health. The episode also covers the strategic use of supplements and the role of brain stimulation therapies, equipping listeners with practical tools to optimize cognitive function and sustain brain health at any age.

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In this episode of Revolution Health Radio, Chris Kresser dives deep into the fascinating world of collagen, the most abundant protein in the human body. He explores collagen's wide-ranging benefits—from supporting vibrant skin, healthy hair, and strong nails, to improving joint health, muscle recovery, gut integrity, and sleep quality. Chris breaks down the science behind collagen supplementation, dispels common myths, and shares practical tips for choosing the best collagen supplements for your needs.

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In this episode of Revolution Health Radio, Chris Kresser talks with Mark Sisson, author of Born to Walk and renowned figure in the ancestral health space, about rethinking our approach to fitness. They challenge the conventional wisdom of chronic cardio and explore the myriad benefits of walking as a foundational movement practice. Mark shares his insights on how modern footwear and a misunderstanding of our evolutionary biology have led us astray, and offers a refreshing perspective on how to optimize our movement for health, longevity, and enjoyment.

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