Previously on Christine Lahti in Space: When Dr Christine Lahti forgets to compliment her bangs, Lunch Lady Lorraine (Special Guest Star Wynonna Judd) puts a curse on her, restricting her to perform surgery with only her feet and elbows, though not at the same time. After a huge fight and/or breakup, Special Guest Star Heather Locklear is furious when Pencil (Daphne Zuniga) brings her new girlfriend Mo’nique to work - Mo’Nique is not a character, but the actual comedian Mo’Nique, who takes it upon herself to change patients charts to diseases she finds more hilarious, ruining Space Nurse’s spotless chart record. Meanwhile The Boss prepares for a date and can’t find her lucky blazer, so she enlists the help of Dr Christine Lahti’s Door (Lisa Kudrow) who may or may not have been eyeing it off behind her back.

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