A philosopher and novelist, she has spent 40 years pondering why we all have a longing to matter. She’s talked with dozens of people about their own need to matter, and tells their stories in her new book, The Mattering Instinct.

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Experiments with mice have shown it’s possible to tinker with and even erase a memory. The goal for neuroscience now is to apply the science to help people struggling with PTSD and other mentally crippling memories.

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These days, despite the internet providing us access to every imaginable source of information, the truth is harder than ever to find.  A conversation about how to sort truth from fiction and why, more than ever, truth matters.

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She has spent over 50 years fighting racism, sexism and sexual violence, often fiercely. Now in her 70’s, her experiences have led her to move past anger toward a more empathic relationship with those she disagrees with.

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The Ig Nobel prizes are awarded every year in a ceremony that is as charming as it is ridiculous, awarding research that itself may seem ridiculous at first sight but often turns out to be unexpectedly useful.

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Babies find things funny long before they understand language – surprising even the author of the most detailed study to date of when and how babies and toddlers develop a sense of humor. And the better they are at getting jokes, the better they are at connecting with others.

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Almost 60 years ago she defied television conventions with her depiction of a young woman succeeding on her own in the big city. And for the last 30 years, along with her own busy career, she's helped keep alive and thriving her father’s dream of a research hospital for children.

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In the almost six years since the beginning of the pandemic he’s developed an on-line personality that’s an exuberant mix of medical expert and next-door neighbor, expressed in engaging videos on TikTok, YouTube and Instagram.

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Alan and executive producer Graham Chedd look ahead to the new season, which includes episodes on how babies who giggle become socially smarter; prizes for science that makes you both laugh and think; why truth is so elusive; and how Marlo Thomas kick started Alan’s movie career as well as helping her father found the St. Jude Children’s Research Hospital.

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How technological innovation has shaped our culture, with lessons from history and even from bees. And how these lessons can help tame and curate the information overload that AI is contributing to on social media.

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