The Model for End-Stage Liver Disease (MELD) score uses the international normalized ratio, creatinine, and total bilirubin to predict 3-month mortality risk, making it a relatively easy and objective measurement for organ allocation, however concerns about equitable distribution remain.

The rising use of expanded criteria donors in an aging patient population makes careful selection of donors and recipients increasingly important. Understand the complex interplay between factors such as donor age, risk index, sex, race, and genetics, as well as the etiology of the liver disease in the recipient, to improve patient outcomes.

Pioneered in pediatric patients in the late 1980s due to insufficient appropriately sized liver donors and high mortality among children on the organ waiting list, living donor liver transplantation is now also employed in the adult patient population.

High demand and low supply remains a constant challenge in liver transplantation, but in some cases extended criteria donor liver allografts provide an effective alternative.

Interview with Federico Villamil.

Interview with Tram T. Tran.

Interview with Michele M. Tana

Viral hepatitis B coinfection with human immunodeficiency virus, hepatitis D virus, or hepatitis C virus – Interview with Richard K. Sterling.

Interview with Robert P. Perrillo.

Interview with George V. Papatheodoridis.