In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing the efficacy of 4 mg vs 8 mg naloxone nasal spray, a recent 29% decrease in overdose deaths associated with the injection route, but a 79% increase in smoking route overdoses, and more!

• Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain, Published in the New England Journal of Medicine, July 2023

• Recreational and Medical Cannabis Legalization and Opioid Prescriptions and Mortality Published in JAMA, January 2024

• Routes of Drug Use Among Drug Overdose Deaths - United States, 2020-2022, Published in the CDC's Morbidity and Mortality Weekly Report, February 2024

• A Regional Analysis of Low Back Pain Treatments in the Military Health System Published in SPINE, a Wolters Kluwer Health Journal, February 2024.

• Comparison of Administration of 8-Milligram and 4-Milligram Intranasal Naloxone by Law Enforcement During Response to Suspected Opioid Overdose — New York, March 2022–August 2023 Published in the CDC's Morbidity and Mortality Weekly Report, February 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing telemedicine associated buprenorphine initiations showing better treatment retention rates than in-office buprenorphine initiations, adolescents participating in more than one high school sport having a 30% greater risk of future opioid misuse, and more!

• Perspective: INTENTION TO TREAT: Prospects for Pain — ITT Episode 14, Published in the New England Journal of Medicine, August 2023

• Rapid Access Addiction Medicine Clinics for People With Problematic Opioid Use, Published in JAMA, November 2023

• Opioids and Youth Athletes, Published in Sports Health, February 2024

• Medications for Alcohol Use Disorder, Published in the American Family Physician, January 2024

• Telemedicine Buprenorphine Initiation and Retention in Opioid Use Disorder Treatment for Medicaid Enrollees Published in JAMA, October 2023

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing a novel sodium channel blocker showing promise in acute pain, ketamine vs. morphine for out of hospital analgesia, factors associated with overdose of young adults, and more!

• Selective Inhibition of NaV1.8 with VX-548 for Acute Pain, published in the New England Journal of Medicine, August 2023

• Ketamine Compared With Morphine for Out-of-Hospital Analgesia for Patients With Traumatic Pain - A Randomized Clinical Trial, Published in JAMA, January 2024

• Lifetime non-fatal overdose experiences among at-risk adolescents and young adults in the emergency department with past-year opioid use in the USA, Published in the Injury Prevention Journal, February 2024

• Systemic Racism as a Determinant of Health Inequities for People With Substance Use Disorder, Published in JAMA, January 2024

• Doctor Versus Artificial Intelligence: Patient and Physician Evaluation of Large Language Model Responses to Rheumatology Patient Questions in a Cross-Sectional Study Published in Arthritis & Rheumatology, October 2023

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing the potential of artificial intelligence in responding to patient inquiries, the association between distance and duration of MOUD treatment, the link between chronic pain and SUD in young adults, and more!

• Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis Published in the Journal of Bone & Joint Surgery, December 2023

• Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a retrospective longitudinal cohort study Published in the Lancet, December 2023

• Barriers to retention in medications for opioid use disorder treatment in real-world practice, Published in the Journal of Substance Use & Addiction Treatment, February 2024

• Appropriate Use of Drug Testing in Clinical Addiction Medicine, Published by the American Society of Addiction Medicine in 2017

• Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum Published in JAMA, June 2023

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing health equity factors associated with abrupt opioid discontinuation, an overview of nociplastic pain, a 66% reduction seen in all-cause mortality for VA patients admitted to SUD residential treatment, and more!

• Factors Associated With Abrupt Discontinuation of Long-Term High-Dose Opioid Treatment Published in JAMA, November 2023

• Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a retrospective longitudinal cohort study Published in the Lancet, November 2023

• Association between high-threshold practices and buprenorphine treatment termination Published in the International Journal on Drug Policy, January 2024

• Nociplastic pain: towards an understanding of prevalent pain conditions. Published in the Lancet, May 2021.

• Effectiveness of residential treatment services for veterans with substance use disorders: A propensity score matching evaluation Published in the Drug and Alcohol Dependence Journal, February 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing the link between opioid prescribing and suicide, the role of GLP-1 receptor agonists in the treatment of SUDs, the positive data on using amitriptyline, pregabalin and duloxetine in diabetic peripheral neuropathic pain, and more!

• Childhood trauma increases risk of chronic pain in adulthood, research to-date highlights Published in Science Daily, December 2023.

• Opioid Prescribing and Suicide Risk in the United States Published in the American Journal of Psychiatry, June 2023

• The impact of fentanyl on state- and county-level psychostimulant and cocaine overdose death rates by race in Ohio from 2010 to 2020: a time series and spatiotemporal analysis Published in the Harm Reduction Journal, January 2024

• The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders Published in the British Journal of Pharmacology, February 2022

• Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial. Published in the Lancet, August 2022

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing the new opioid antagonist nalmefene, the 6% increase in buprenorphine prescribing associated with the x-waiver repeal, brain signals associated with chronic pain, and more!

• Scientists Find Brain Signals of Chronic Pain, Published in the NY Times, May 2023

• Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following open major hepatectomy: an open-label, randomised, controlled, non-inferiority trial- Published in the Lancet, August 2023

• Stronger, longer, better opioid antagonists? Nalmefene is NOT a naloxone replacement Published in the International Journal on Drug Policy, January 2024

• The misguided reason why providers aren't prescribing more buprenorphine for opioid use disorder Published by STAT, January 2024

• Effectiveness of an unsupervised online yoga program on pain and function in people with knee osteoarthritis. A randomized clinical trial. Published in the Annals of Internal Medicine, September 2022

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing buprenorphine vs methadone treatment for OUD, the link between gabapentinoids and COPD exacerbations, the significant decrease in overdose mortality rates seen in Sweden after rolling out take-home naloxone, and more!

• Gabapentinoids and Risk for Severe Exacerbation in Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study, Published in the Annals of Internal Medicine, January 2024

• Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies Published in the Lancet Journal of Psychiatry- May 2023

• Addressing the Spectrum of Opioid Misuse Prevention, Treatment, and Recovery in Rural Washington State Communities: Provider Identified Barriers and Needs Published in the Community Mental Health Journal, January 2024

• Distribution of intranasal naloxone to potential opioid overdose bystanders in Sweden: effects on overdose mortality in a full region-wide study Published in the BMJ Open, January 2024

• Association of therapies with reduced pain and improved quality of life in patients with fibromyalgia: a systematic review and meta-analysis Published in JAMA Internal Medicine, January 2021

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing the benefit of physical therapy over glucocorticoid injections in osteoarthritis of the knee, the link between adolescent mortality data and presentation to an emergency department for an alcohol-related cause, and more!

• Physical Therapy vs Glucocorticoid Injection for Osteoarthritis of the Knee Published in the New England Journal of Medicine, April 2020

• Reducing Opioid Use for Chronic Pain With a Group-Based Intervention AND responses, Published in JAMA, May 2023

• Mortality in Adolescents and Young Adults Following a First Presentation to the Emergency Department for Alcohol Published in Academic Emergency Medicine, December 2023

• Maddalena Opioid Switching Score in patients with cancer pain Published in the Journal of Pain, Jan 2023

• Prescription psychostimulants for the treatment of amphetamine-type stimulant use disorder: A systematic review and meta-analysis of randomized placebo-controlled trials Published in the Journal of Addiction, Oct 2023

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing methadone treatment in patients with cancer, undiagnosed mood disorders in 75% of study patients with musculoskeletal pain, telehealth benefits in the treatment of OUD, and more!

• Juggling Two Full-Time Jobs - Methadone clinic Engagement and Cancer Care, Published in the New England Journal of Medicine, November 2023

• Maternal Opioid Use Disorder and the Risk of Postneonatal Infant Mortality, Published in JAMA Pediatrics, May 2023.

• Undiagnosed Mood Disorders and Sleep Disturbances in Primary Care Patients with Chronic Musculoskeletal Pain Published in the Pain Medicine Journal, Sept 2013

• Telemedication for Opioid Use Disorder: A New Approach for Treatment Published in Telemedicine Reports, Nov 2023.

• SAMHSA 2022 National Survey on Drug Use and Health (NSDUH) Releases Published by the Substance Abuse and Mental Health Services Administration, Nov 2023