Director of the Center for Biologics Evaluation and Research (CBER) at the Food and Drug Administration, Dr. Peter Marks, joins Dr. Marc Siegel and discusses the Pfizer vaccine for children ages 5 to 11 and the data that shows it is safe and effective, as well as boosters and vaccine timing for durable immunity.

Pediatrician Dr. Dan Rauch and his guest, Dr. Frank Esper, explain the FDA and CDC authorization of COVID vaccines for children, the dosing for younger kids, and why vaccinations are effective, safe, and an important part of protecting children from infection and the long-term effects of the virus.

Chief of Pediatric Infectious Diseases at Tufts Children’s Hospital and Member of the FDA's VRBPAC, Dr. H. Cody Meissner, joins Dr. Marc Siegel and offers insights into the considerations made when reviewing the data to determine whether or not to authorize COVID vaccines for children, the dosage that should be used, and how the vaccines will be distributed.

Stanford Professor of Global Health, Infectious Diseases, and Pediatrics, Dr. Yvonne Maldonado, joins Dr. Marc Siegel and offers insight into the clinical trials she’s led looking at the safety and efficacy of COVID vaccines for children. And, she explains how vaccinating pregnant women benefits their babies.

Member of the FDA's Vaccines Advisory Committee and Cincinnati Children's Hospital Medical Center Director of Infectious Diseases, Dr. Paul Spearman, joins Dr. Marc Siegel and discusses the data and science reviewed for the FDA’s decision to authorize emergency use of vaccines in children 5 to 11. Hear about dosage, distribution considerations, and next steps to get shots in children’s arms.

Pediatrician Dr. Seema Awatramani talks with pediatric epidemiologist and Pediatric Stewardship Director, Dr. Jennifer Lighter, and Director of the Division of Maternal Fetal Medicine at NYU Langone Health, Dr. Ashley Roman, about the pending approval of the COVID vaccine for children under 12, the health risks a COVID infection presents to pregnant women, the benefits of the COVID vaccine during pregnancy, and their encouraging research showing that expectant moms transfer protection against COVID 19 to the fetus after being vaccinated.

American Medical Association President, Dr. Gerald E. Harmon, joins Dr. Marc Siegel and discusses public health and vaccine hesitancy, as well as the impact the pandemic has had on healthcare workers and availability of medical services and medications.

Chief Science Officer for the White House COVID-19 Response Team, Dr. David Kessler, joins Dr. Marc Siegel and shares insight into the Administration’s expectations concerning vaccines for children, what that might look like in schools and pediatricians’ offices, and where he thinks we are headed with the pandemic in the next several months.

Dean of Brown University’s School of Public Health, Dr. Ashish Jha, joins Dr. Marc Siegel and discusses at home COVID testing, masking, global distribution of vaccines, boosters, and what he thinks we'll see this winter, as the pandemic continues.

Dr. Marc Siegel and his guest, Professor of Microbiology and Immunology, and Member of the Vaccines and Related Biological Products Advisory Committee (VRBPAC), Dr. Stanley Perlman, discuss the data reviewed and questions considered as the FDA meets to decide whether or not to give approval for administering COVID boosters, mixing and matching booster doses, and vaccines for children under 12.