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We’ve already learned a lot about electrophilic aromatic substitution (EAS) and benzene, but guess what? There’s even more to learn! In this episode of Crash Course Organic Chemistry we’ll revisit our old friends the Friedel-Crafts reactions and learn some of their limitations and look at where substitution happens when there are multiple directing groups on a benzene ring. Plus we’ll introduce some benzylic reactions!
Episode Sources:
Master Organic Chemistry: Reactions on the “Benzylic” Carbon: Bromination And Oxidation
Indigo – Ben Valsler, Chemistry World
Travis, A.S. (2009). Anilines: Historical Background. In PATAI'S Chemistry of Functional Groups, Z. Rappoport (Ed.). https://doi.org/10.1002/9780470682531.pat0383
Master Organic Chemistry: EAS Reactions (3) – Friedel-Crafts Acylation and Friedel-Crafts Alkylation
Solomons, G.T. and Fryhle, C.B. (2011) Organic Chemistry. 10th Edition, John Wiley & Sons, Inc., Hoboken.
Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
***
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Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
DL Singfield, Jeremy Mysliwiec, Shannon McCone, Amelia Ryczek, Ken Davidian, Brian Zachariah, Stephen Akuffo, Toni Miles, Oscar Pinto-Reyes, Erin Nicole, Steve Segreto, Michael M. Varughese, Kyle & Katherine Callahan, Laurel A Stevens, Vincent, Michael Wang, Stacey Gillespie, Jaime Willis, Krystle Young, Michael Dowling, Alexis B, Rene Duedam, Burt Humburg, Aziz Y, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Junrong Eric Zhu, Alan Bridgeman, Rachel Creager, Jennifer Smith, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, Brandon Westmoreland, team dorsey, Trevin Beattie, Divonne Holmes à Court, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Khaled El Shalakany, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, William McGraw, Andrei Krishkevich, ThatAmericanClare, Rizwan Kassim, Sam Ferguson, Alex Hackman, Jirat, Katie Dean, neil matatall, TheDaemonCatJr, Wai Jack Sin, Ian Dundore, Matthew, Justin, Jessica Wode, Mark, Caleb Weeks
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Disease doesn’t care about national borders. The pathogen hopping the red eye from Berlin to Boston doesn’t need a passport. So, in order to be proactive about protecting our health, we need to think globally. In this episode of Crash Course Public Health, we’re traveling around the world to look struggles and triumphs of public health on a global scale.
Chapters:
Introduction to Global Health 00:00
The WHO 2:15
Communicable Disease 3:26
Non-communicable Disease 6:11
Foreign Aid 8:33
Economic Inequality 11:57
Review & Credits 14:18
Check out our shared playlist with APHA: https://www.youtube.com/playlist?list=PLDjqc55aK3kywF2dd97_Jh5iP0d2ARhdo
Vanessa’s channel: https://www.youtube.com/braincraft
Sources: https://docs.google.com/document/d/1OHJiQ1njj5jWJC1YLDBzQgKC1QfnVgqJbbpK6qs7ekA/edit?usp=sharing
***
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Dylan Mandelblatt, Katie, Hilary Sturges, Austin Zielman, Tori Thomas, Justin Snyder, Hasan Jamal, DL Singfield, Amelia Ryczek, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Michael Wang, Stacey J, Burt Humburg, Allyson Martin, Aziz Y, Shanta, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Rachel Creager, Breanna Bosso, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, team dorsey, Trevin Beattie, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, Les Aker, William McGraw, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Jirat, Pineapples of Solidarity, Katie Dean, Wai Jack Sin, Ian Dundore, Justin, Mark, Caleb Weeks
__
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Time for another Bad Astronomy break.
Check out the Crash Course Astronomy solar system poster here: http://store.dftba.com/products/crashcourse-astronomy-poster
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PBS Digital Studios: http://youtube.com/pbsdigitalstudios
Follow Phil on Twitter: https://twitter.com/badastronomer
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In which John Green sings the Crash Course intro song, is interrupted by quite possibly the loudest truck in all existence, and attempts to pronounce the most difficult word in the history of words - which is apparently "misanthropy."
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
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Today, Clint Smith will teach you about the legendary writer Toni Morrison. Morrison is best known for her novels which chronicle the experiences of Black Americans throughout history. She was the first Black American Woman to win a Nobel Prize for Literature.
Clint's book, How the Word is Passed is available now! https://bookshop.org/books/how-the-word-is-passed-a-reckoning-with-the-history-of-slavery-across-america/9780316492935
Want to learn more about Toni Morrison's work? Check out these videos from Crash Course Literature:
Slavery, Ghosts, and Beloved: Crash Course Literature 214: https://www.youtube.com/watch?v=6lQyPgaakY4
Sula: Crash Course Literature 309: https://www.youtube.com/watch?v=eAHYT5gIPZg
VIDEO SOURCES
Michelle Alexander, The New Jim Crow: Mass Incarceration in the Age of Colorblindness (New York: New Press, 2010).
Nellie Y. McKay, ed. Critical Essays on Toni Morrison (Boston: G.K. Hall & Co., 1988).
Philip Page, Dangerous Freedom: Fusion and Fragmentation in Toni Morrison’s Novels (Jackson: University Press of Mississippi, 1995).
Toni Morrison: The Pieces I Am. Directed by Timothy Greenfield-Sanders. June 21, 2019.
https://www.archives.gov/news/articles/toni-morrison-death-2019
Watch our videos and review your learning with the Crash Course App!
Download here for Apple Devices: https://apple.co/3d4eyZo
Download here for Android Devices: https://bit.ly/2SrDulJ
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Katie, Hilary Sturges, Austin Zielman, Tori Thomas, Justin Snyder, DL Singfield, Amelia Ryczek, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Stacey Gillespie (Stacey J), Burt Humburg, Allyson Martin, Aziz Y, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Rachel Creager, Breanna Bosso, Matt Curls, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, team dorsey, Trevin Beattie, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, Les Aker, William McGraw, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Jirat, pineapples of solidarity, Katie Dean, Wai Jack Sin, Ian Dundore, Justin, Mark, Caleb Weeks
__
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In this episode of Crash Course Psychology, Hank takes a look at a few experiments that helped us understand how we develop as human beings. Things like attachment, separation anxiety, stranger anxiety, and morality are all discussed... also, a seriously unpleasant study with monkeys and fake mothers.
Want more videos about psychology? Check out our sister channel SciShow Psych at https://www.youtube.com/scishowpsych!
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Chapters:
Introduction: Attachment 00:00
Harlow's Monkey Mother Experiment 0:47
Touch 2:16
Familiarity 3:01
Attachment Styles: Secure, Insecure Ambivalent, & Insecure Avoidant 3:57
The Importance of Attachment Styles 5:24
Developing Self-Concept 6:45
Parenting Models: Authoritarian, Permissive, & Authoritative 7:36
Kohlberg's Theory of Moral Development 8:18
Preconventional Morality Phase 9:27
Conventional Morality Phase 9:44
Postconventional Morality Phase 10:00
Review & Credits 10:48
--
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
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We don’t know what the next big scientific breakthrough is going to be or what futuristic diseases we’ll encounter. But when it comes to our health, we actually have a pretty good idea of what could be next. And we also have some ideas about what we need to do today to prepare. In this final episode of Crash Course Public Health, we’re going to take a look into the future with some roadmaps from the present.
Chapters:
Looking to the Future 00:00
Disease Surveillance 2:55
A Planetary Approach 5:05
Technology & Misinformation 8:12
Health Equity 10:46
Review & Credits 11:39
Check out our shared playlist with APHA: https://www.youtube.com/playlist?list=PLDjqc55aK3kywF2dd97_Jh5iP0d2ARhdo
Vanessa’s channel: https://www.youtube.com/braincraft
Sources: https://docs.google.com/document/d/1OHJiQ1njj5jWJC1YLDBzQgKC1QfnVgqJbbpK6qs7ekA/edit?usp=sharing
***
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Dylan Mandelblatt, Katie, Hilary Sturges, Austin Zielman, Tori Thomas, Justin Snyder, Hasan Jamal, DL Singfield, Amelia Ryczek, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Michael Wang, Stacey J, Burt Humburg, Allyson Martin, Aziz Y, Shanta, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Rachel Creager, Breanna Bosso, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, team dorsey, Trevin Beattie, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, Les Aker, William McGraw, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Jirat, Pineapples of Solidarity, Katie Dean, Wai Jack Sin, Ian Dundore, Justin, Mark, Caleb Weeks
__
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This week Craig Benzine talks about the importance of elections in the strongest branch of the U.S. Government: Congress. He'll talk about the frequency of elections in the Senate and House, the typical characteristics of a candidate, and the motivating factors our congresspeople follow to get re-elected.
Produced in collaboration with PBS Digital Studios: http://youtube.com/pbsdigitalstudios
Support is provided by Voqal: http://www.voqal.org
Chapters:
Introduction: Congressional Elections 00:00
How Congressional Elections Work 0:59
How Congressional Candidates Get Elected 2:16
Characteristics of Congressional Candidates 3:05
Incumbency Advantage 4:21
The Electoral Connection & Why Congressional Elections Matter 6:01
Credits 8:25
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
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Nearly every environment on Earth — and that includes animals — is home to some kind of parasite. Today we’re going to talk about parasites not just because they’re an essential part of their ecosystems, but also because by studying them we can learn more about their hosts and even their shared evolution and ecology. So stick with us, this one is going to get a little weird!
🦔🐒🐝🐛🐘🐍🐀🐠 🐢🐋🐅🦓🦇🦜🐜🪱🦑 🦀🐊
Learn more about Rae here! https://www.raewynngrant.com
Watch our videos and review your learning with the Crash Course App!
Download here for Apple Devices: https://apple.co/3d4eyZo
Download here for Android Devices: https://bit.ly/2SrDulJ
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Vincent, Emilee Murphy, Michael Wang, Jordan willis, Krystle Young, Michael Dowling, Alexis B, Rene Duedam, Burt Humburg, Aziz, Nick, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Junrong Eric Zhu, Alan Bridgeman, Rachel Creager, Jennifer Smith, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, Brandon Westmoreland, team dorsey, Trevin Beattie, Divonne Holmes à Court, Eric Koslow, Indika Siriwardena, Khaled El Shalakany, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, William McGraw, Andrei Krishkevich, Sam Ferguson, Eric Prestemon, Jirat, TheDaemonCatJr, Wai Jack Sin, Ian Dundore, Jason A Saslow, Justin, Jessica Wode, Mark, Caleb Weeks
__
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#CrashCourse #Zoology #PBSNature
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In which John Green teaches you about the poetry of Sylvia Plath. When a lot of people think about Sylvia Plath, they think about her struggles with mental illness and her eventual suicide. Her actual work can get lost in the shuffle a bit, so this video really tries to focus on the poetry. You'll learn about Sylvia Plath's role as a feminist poet, and you'll also learn about her extraordinary ability to recreate the experiences of real life in a beautiful and relatable way.
Consider supporting local bookstores by purchasing your books through our Bookshop affiliate link https://bookshop.org/shop/complexly or at your local bookseller.
Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse
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