BMAA is a toxin that may cause some forms of sporadic ALS. Here we discuss how L-serine, an inexpensive, widely available amino acid supplement, might block BMAA toxicity and thus be of use for preventing or slowing ALS progression.

Acuscope is a machine that delivers a very small amount of electric current to muscles. In this podcast we report that acuscope treatment appears fairly safe, but is expensive and has shown no clear benefit in slowing ALS.

Curcumin is an ingredient in the spice tumeric and in curry powder. It has multiple plausible mechanisms by which it might slow ALS progression. There are 3 people with validated ALS diagnoses who recovered significant lost motor function (ALS reversals) on forms of it. Here we discuss the specific curcumin formulation and dosage that we think is promising enough to warrant further study in ALS.

Inosine is a naturally occurring oral supplement that raises blood urate levels. In this podcast, we discuss ways this might slow ALS progression and why it needs careful blood and urine monitoring

CuATSM is a very promising ALS treatment that is in development. Here we discuss copper metabolism in ALS, why this specific therapy might help and why less complicated copper supplements are unlikely to be of any benefit.

Basis in an over the counter supplement containing nicotinamide ribose and pterostilbene. In this podcast, we review the theories on how this might help a person with ALS, as well as the potential risks and costs involved.

In this podcast, we discuss one of the most requested ALSUntangled reviews of all time-a complicated treatment cocktail described in a book written by a patient with slowly progressive ALS called "Eric is Winning."

ALSUntangled is an internet based program that reviews alternative and off label treatments, with the goal of helping people with ALS make more informed decisions about them. This podcast describes how the program works.