'Why we do What we do in Cardiology'

CVD: 2023 Major Updates in General Cardiology


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Key Highlights:

  • Lodoco is the first anti-inflammatory approved for reducing cardiovascular events in ASCVD patients.
  • Bempedoic acid offers an alternative for high-risk patients who can't tolerate statins.
  • Semaglutide has emerged as a powerful tool for reducing cardiovascular events in overweight or obese patients with pre-existing CVD.
  • Recaticimab is a long-acting injectable PCSK9 inhibitor requiring less frequent dosing than existing options.
  • Focus on LDL Cholesterol: New data supports the "power of zero" for coronary artery calcium, prioritizing LDL reduction only in those with established atherosclerosis.
  • Treat-to-Target vs. High-Intensity Statins: A study (LODESTAR) shows the non-inferiority of the treat-to-target approach, adding to ongoing discussions about cholesterol management strategies.
  • Overall:

    • Shift towards prevention: 2023 saw a significant focus on research and interventions aimed at preventing cardiovascular disease rather than solely treating established cases.
    • Emphasis on early intervention: Studies like POP-HT highlight the importance of monitoring and modifying risk factors in young adulthood.
    • ...more
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      'Why we do What we do in Cardiology'By Bishnu Subedi


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