🔹 High-yield reversible causes of constipation? (02:26)

🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)

🔹 Osmotic vs Stimulant Laxatives (15:06)

🔹 Suppositories and enemas? (25:39)

🔹Best practices with opioid induced constipation (34:05)

📌  Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! 

Use the code CORE50 to get 50% off your first month with Freed

📌 Earn CME credit with ACP for this episode! CME-MOC credit 

📌 Transcript and Show Notes

Tags: CoreIM, IMCore, Gastroenterology, GI Pharmacology, Digestive Health, Primary Care, Medical Education, Physician Assistant, Nurse Practitioner, Medical Student, Laxatives, Stool Softeners, Senna, Bisacodyl, Polyethylene Glycol, Bowel Regimen, Magnesium Citrate, Lactulose

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV.

Listen to this latest episode of Beyond Journal Club, a collaboration between CoreIM and NEJM Group, where we put research into context, telling the story of how we arrived at the current standard of care, appreciating the clinical question of the trial at hand, and interpreting what the findings may mean for these patients.

🔹 Sponsor:  NEJM Fellowship Program, click here to learn more and/or apply!

🔹 Transcript and Show Notes

Timestamps:

(02:25) | HIV PrEP Daily Truvada and Descovy

(07:48) | On-Demand Prep

(13:25) | Purpose Trials

(20:56) | Discussion of Effectiveness to Efficacy

Tags:  CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, HIV Prevention, Infectious Disease

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.

🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! 

Use the code CORE50 to get 50% off your first month with Freed

🔹 Transcript and Show Notes

Timestamps:

(02:17) | Pearl 1: What makes Lp(a) unique? How does it raise ASCVD risk?

(10:32) | Pearl 2: Who should be tested for Lp(a)? When and why?

(16:54) | Pearl 3: Understanding and interpreting Lp(a) levels

(24:04) | Pearl 4: How does an elevated Lp(a) affect management?

(37:05)| Pearl 5: The role of aspirin and PCSK9 inhibitors in Lp(a)

Tags: CoreIM, Internal Medicine, Primary Care, Preventive Cardiology, Atherosclerosis, Lipid Management, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!

🔹 Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! 

Use the code CORE50 to get 50% off your first month with Freed

🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.

Transcript and Show Notes

Timestamps:

(02:07) | Pearl 1: Reframing Provoked vs. Unprovoked to Reversibility

(09:12) | Pearl 2: How can Virchow's Triad help us categorize the etiology of a clot?

(17:01) | Pearl 3: What factors affect anti-thrombin III, Protein C and Protein S deficiency

(28:50) | Pearl 4: Is the Factor V Leiden or Prothrombin Gene Mutation as important as the family history?

(38:41) | Pearl 5: Spaced Repetition of Learning Points

Tags: CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine, hematology

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?

Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease on this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.

🔹 Transcript and Show Notes

🔹 Behind The Scenes YouTube Video

This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.

Timestamps:

(02:24) | Introduction to Plastic's Key Players

(07:59) | Bradhill/Observational Work

(10:33) | APAChE Study Deep Dive

(18:03) | Discussion

📢 Special Thanks:

🎙️ Audio Editing: Jerome Reyes

📊 Graphics: Dr. Jimin Hwang

Tags:

CoreIM, Environmental Health, Medical Education, IMCore, Public Health, Clinical Pearls, Physician, Medical Student, Nurse Practitioner, Epidemiology

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music therapy in hospice care, sharing moving stories and clinical insights.

🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.

🔹 Transcript and Show Notes

Timestamps:

(00: 39) | 1st: What is Music Therapy in Hospice?

(07:59) | 2nd: A Powerful Story

(14:19) | 3rd: Challenges in the Field of Music Therapy

Tags:  IMCore, CoreIM, primary care, palliative care, end-of-life, oncology nurse practitioner, pharmacist, physician assistant

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

Incidental fibrosis on CT —what now? What does prone imaging tell you? Is it fibrosis, aspiration, or atelectasis? And once you diagnose ILD, does the “alphabet soup” really matter for treatment? Antifibrotics vs. immunosuppression?

Plus, how do we bridge the gap when social barriers make care unsafe?

🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.

Transcript and Show Notes

Timestamps:

(01:26) | Deep Dive 1

(06:38) | Deep Dive 2

(12:37) | Deep Dive 3

(21:13) | Deep Dive 4

(28:06) | Deep Dive 5

Tags: CoreIM, Internal Medicine, Pulmonology, Clinical Pearls, Medical Education, IMCore, Radiology, Hospitalist, Physician Assistant, Nurse Practitioner, Medical Student, interstitial lung disease

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

SPEP vs. UPEP? What does it tell you and not tell you? What is the role for immunofixation and free light chains in diagnosis? Learn about paraneoplastic antibodies with MGCS and its renal, neurologic, and dermatologic manifestations!

Sponsor: Freed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! 

Use the code CORE50 to get 50% off your first month with Freed

🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door. Use the code factorpodcast for a special discount at factor75.com.

Behind The Scenes Youtube Interview with Dr. Vincent Rajkumar

Transcript and Show Notes

Timestamps:

(01:26) | Pearl 1: What is a monoclonal gammopathy? What is our expected clinical presentation?

(10:12) | Pearl 2: What is our initial workup? Understanding SPEP, Immunofixation, and Free Light Chains

(24:13) | Pearl 3: Do we need urine testing? When urine testing is necessary and when it is not.

(26:26) | Pearl 4: How should we differentiate monoclonal gammopathies? The continuum of MGUS, SMM, and MM.

(41:35) | Pearl 5: Demystifying Monoclonal gammopathy of clinical significance (MGCS)

Tags: CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

How do you differentiate immune checkpoint inhibitor-related adverse events aka IrAEs from other conditions like infection? Join as we go through pneumonitis, colitis, dermatitis and endocrinopathies due to immune checkpoint inhibitor toxicity!

Transcript and Show Notes

ICIs & IrAEs 101 Episode

Behind The Scenes video

Sponsor:

• Interested in integrating Glass AI into your EMR? Reach out to [email protected].
• Use code "COREIM" for one month free access of AI queries through Glass Pro.

Subscribe to Core IM’s YouTube Channel for more behind the scenes, whiteboard animations and more!

Get CME-MOC credit with ACP!

Timestamps:

(03:14) | Pearl 1

(13:34) | Pearl 2

(24:42) | Pearl 3

(30:34) | Pearl 4

(35:21) | Pearl 5

Tags: CoreIM, Internal Medicine, ClinicalPearls, Skin Toxicity, Medical Education, IMCore, oncology, hospitalist, physician assistant, nurse practitioner, medical student

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy

YouTube Videos

1. Anion Gap Metabolic Acidosis: https://youtu.be/oE0lygmMANM
2. Inhaler Delivery Systems: https://youtu.be/yYPdjClm9Bg
3. Iron Deficiency in Pregnancy https://youtu.be/xTzYSXUbLsc

Subscribe to Core IM’s YouTube Channel for more behind the scenes, whiteboard animations and more!

Timestamps:

01:27 | Anion Gap Metabolic Acidosis (Dr. Nick Villano)

02:52 | Inhaler Delivery Systems (Dr. Allie Sheridan)

04:44 | IDA in Pregnancy (Dr. Michael Auerbach)

Tags:IMCore, Medical Education, IDA, hospitalist medicine, hospitalist, primary care, nurse practitioner, chalktalks, hematology, asthma, COPD, pregnancy care, Medical Podcast, Clinical Teaching

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Washington Red Raspberries for recipes, farmers' stories, and which grocery stores carry: https://www.coreimpodcast.com/redrazz
* Sponsor: FIGS! Use code FIGSRX for 15% off: https://wearfigs.com


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy