Decreased insulin clearance may be first step on path to insulin resistance. 

http://bit.ly/2C165Gy

Tender joint count may confound assessment of RA inflammation.

http://bit.ly/2G8H7Jv

Common AEDs confer modestly increased risk of major congenital malformations. 

http://bit.ly/2RPeH91

ACR, NPF unveil psoriatic arthritis treatment guideline. 

http://bit.ly/2L6NRq8

Study investigates statin-diabetes link.

http://bit.ly/2L7G8Ih

Should metabolic syndrome be renamed circadian syndrome?

http://bit.ly/2B681fz

Phone app diagnoses STEMI nearly as well as ECG.

http://bit.ly/2UtITIr

Fewer insured may have helped slow health spending growth in 2017. 

http://bit.ly/2rrQh9J

In this special edition of the MDedge Daily News, MDedge Hematology Editor, Mary Ellen Schneider, and Nick Andrews present some of the most important news with full comments from researchers and clinicians. 

CLL resistance mechanism to venetoclax identified.

http://bit.ly/2RR6qB6

Rivaroxaban may reduce VTE risk in cancer patients.

http://bit.ly/2QiIhaf

New treatments promise sickle cell "cure" for all ages.

http://bit.ly/2EaZL0X

Gut bacteria influence HCT outcomes.

http://bit.ly/2PrpzYH

Email the podcast: [email protected]

ONC releases draft strategy on reducing EHR burden.

http://bit.ly/2PndeET

DIuretics are linked to diabetic amputations in type 2 diabetes.

http://bit.ly/2E1CdeR

Direct acting oral anticoagulant pause yields favorable outcomes for patients with atrial fibrillations.

http://bit.ly/2zMwpmu

Hepatitis C debrief: Therapy has matured, access issues remain. 

http://bit.ly/2E1CvCt

MDedge Psychast: Jack Drescher - Conversion Therapy.

http://bit.ly/2QfTyI2

Combined novel risk factors raise coronary event rates. 

http://bit.ly/2EdmNox

The latest insulin results for Alzheimer's muddied by malfunctioning inhaler.

http://bit.ly/2Edn0bj

It's time for universal HCV screening in the ED.

http://bit.ly/2KUTfN9

Sickle Cell Disease guidelines release set for early 2019.

http://bit.ly/2QdwPfL

Follow Nick Andrews on twitter @tribnic and contact MDedge: [email protected]. 

Today's Stories: 

High prices drive underuse of insulin.

http://bit.ly/2QAsbIf

Methotrexate fails to cut CVD events in a large randomized controlled trial. 

http://bit.ly/2UaLCGu

Single-item scale is effective for assessing sleep quality. 

http://bit.ly/2ribWkC

Opioids appear safe for inpatient sickle cell pain.

 http://bit.ly/2SnhkOU

MDedge Cardio Cast

AHA Part I (http://bit.ly/2U9OT8Z)

AHA Part II (http://bit.ly/2BNoLd1)

Contact MDedge Podcasts: [email protected]

Daily News Stories:

New treatments promise sickle cell "cure" for all ages.

http://bit.ly/2BNoLd1

Apixaban edges other DOACS for octogenarians.

http://bit.ly/2Q91J9a

Heavy menstrual bleeding in teens is often linked to bleeding disorders.

http://bit.ly/2DXISqd

Tanning use disorder should be added to the DSM-V

http://bit.ly/2rjhlrH

Three commonly used quick cognitive assessments often yield flawed results. 

http://bit.ly/2AMduYN

DMARDs improve vascular abnormalities in early Rheumatoid Arthritis.

http://bit.ly/2RpfRro

HIV prevention: Mandating insurance coverage for PrEP.

http://bit.ly/2Rvhdku

PCOS is linked to increased cancer risk in postmenopausal women.

http://bit.ly/2U2M2yJ

MDedge Psychcast: 

Physical activity may count more for women who keep the pounds off. 

http://bit.ly/2DOwA3n

Review of pediatric data indicates a link between vitamin D levels and atopic dermatitis severity. 

http://bit.ly/2FJ8ZUo

Nerve growth factor antibody cuts OA pain with low adverse events. 

http://bit.ly/2DOmOhK

Harnessing the power of urine tests in pain care.

http://bit.ly/2Rkixql