In this week’s episode, we discuss antibiotics, Kennedy, mirrors and education—all from Seville, Spain. First up: fluoroquinolones are a class of antibiotics that includes cipro, and are now understood to cause a whole host of serious health problems, from tendon rupture to heart damage to death. Over-reliance on pharmaceutical solutions to human problems is making us sicker. Then: scientists are worried about Kennedy, because he “rejects established science,” like how effective the mRNA shots are against Covid. Also: what is going on with mirrors, and why are people so quick to decide that it’s obvious? Finally: education should include mirrors and magnets and big messy physical games that require coordination of both individual bodies and people.

*****

Our sponsors:

ARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to www.tryarmra.com/DARKHORSE to get 15% off your first order.

Timeline: Accelerate the clearing of damaged mitochondria to improve strength and endurance: Go towww.timeline.com/darkhorse and use code darkhorse for 10% off your first order.

Sundays: Dog food so tasty and healthy, even husbands swear by it. Go to www.sundaysfordogs.com/DARKHORSE to receive 35% off your first order.

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://a.co/d/dunx3at

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

The Achilles Heel of antibiotics: https://naturalselections.substack.com/p/the-achilles-heel-of-antibiotics

Nature goes after Kennedy: https://www.nature.com/articles/d41586-025-00439-y

Mirror tweet: https://x.com/IterIntellectus/status/1891878417580101926

Support the show

In this week’s episode, we discuss changes in global health from Barcelona, as indicated by how much public coughing is taking place now. This segues into a discussion of cancer, mRNA, trade-offs, and complex systems. Then: what DOGE needs to understand about science, which is not inherently efficient. What are indirect costs on federal grants, why are they necessary, and why do they vary? And: how does having indirect costs create perverse incentives by university administrators to privilege scientists over non-scientists, and Big Science over (regular) science. Specifically, science in the West is failing because fast, expensive empirical science is nearly always favored over slow, cheap, and/or theoretical science. Universities get richer, and Big Scientists get promoted, but grad students don’t learn how to be scientists, and we all lose out on having basic scientific questions answered, which will ultimately be our downfall. Also: the Ship of Theseus.

***** 

Our sponsors:

Pique’s Nandaka: delicious mushroom, tea, and chocolate drink that provides all day energy. Get 20% off plus free frother+beaker at www.Piquelife.com/DARKHORSE

Fresh Pressed Olive Oil Club: Scrumptious & freshly harvested. Go to www.GetFreshDarkHorse.com to get a bottle of the best olive oil you’ve ever had for $1 shipping.

CrowdHealth: Pay for healthcare with crowdfunding instead of insurance. It’s way better. Use code DarkHorse at JoinCrowdHealth.com to get 1st 3 months for $99/month.

***** 

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/ 

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com 

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned) 

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org 

***** 

Mentioned in this episode:

Evolutionary Lens #84, June 2021 (Hey YouTube: Divide by Zero): https://odysee.com/@BretWeinstein:f/EvoLens84:b

Research University Classifications for 2025: https://carnegieclassifications.acenet.edu/carnegie-classification/research-designations-faqs/

NSF’s Higher Education Research and Development (HERD) Survey: https://ncses.nsf.gov/surveys/higher-education-research-development/2023

Metamorphosis: https://naturalselections.substack.com/p/metamorphosis

Support the show

Bret Weinstein speaks with Jo Ellis, the transgender pilot with the Virginia National Guard who was wrongfully targeted by social media users as the captain of the Black Hawk helicopter that tragically crashed.

Find Jo Ellis on X at https://x.com/JoEllisReally

*****

Sponsors:

Jolie: For your best skin & hair guaranteed head to http://jolieskinco.com/DARKHORSE to try it out for yourself with FREE shipping.

MUD\WTR: Start your new morning ritual & get up to 43% off your @MUDWTR with DARKHORSE at  http://mudwtr.com/DARKHORSE #mudwtrpod

Helix: Excellent, sleep-enhancing, American-made mattresses. Go to http://www.HelixSleep.com/DarkHorse for 27% Off Sitewide + 2 Free Dream Pillows
with Mattress Purchase + Free Bedding Bundle (2 Dream Pillows, Sheet Set, and Mattress Protector) with any Luxe or Elite Mattress Order *This is their best offer- good through February 20th*


*****

Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.org

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

Support the show

In this week’s episode, we discuss the relationship between infectious and chronic disease, and between germ theory and terrain theory of disease. Pathogens are real, and exogenous treatments like antibiotics can kill them. The health of the body is affected by diet, exercise, stress, and the microbiome, all of which can affect how susceptible a person is to getting sick from pathogens. We discuss gastric ulcers, Covid-19, pneumococcal disease, and comorbidities. Also: how do traditional vs modern diets affect the health, dental and otherwise, of people? Why do pre-industrial people not get cavities, or need orthodontia? Why do squirrels fed by humans develop similarly malformed skulls as babies fed modern diets? Finally: do we have a responsibility to point out the carnage that will result as the Trump administration goes after decades of entrenched interests?

*****

Our sponsors:

Caraway: Non-toxic, beautiful, light ceramic cookware. Save $150 on a cookware set over buying individual pieces, and get 10% off your order at http://carawayhome.com/DarkHorse.

Manukora: the most flavorful, delicious, and nutritious honey you’ll ever have. Get $25 off your starter kit at http://www.Manukora.com/DarkHorse

ARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to http://www.tryarmra.com/DARKHORSE to get 15% off your first order.

Mentioned in this episode:

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

RFK Jr on chronic and infectious disease: https://x.com/ChildrensHD/status/1885018213701800387

RFK Jr on The Real Anthony Fauci: https://amzn.to/40INnxF (commission earned)

Marshall et al 1985. Attempt to fulfil Koch's postulates for pyloric Campylobacter. Med J Aust. 142:436–9:https://onlinelibrary.wiley.com/doi/abs/10.5694/j.1326-5377.1985.tb113443.x

Evolutionary Lens Livestream #88 – w discussion of Covid x comorbidities: https://www.youtube.com/watch?v=KSWu6DUFFt4&t=337s

Hanada et al 2021. Multiple comorbidities increase the risk of death from invasive pneumococcal disease under the age of 65 years. Journal of Infection and Chemotherapy, 27(9): 1311-1318: https://www.sciencedirect.com/science/article/abs/pii/S1341321X21001252

Nutrition and Physical Degeneration, by Weston Price (1939): https://amzn.to/4jXciXl (commission earned)

Chandler et al 2025. Morphological change in an isolated population of red squirrels (Sciurus vulgaris) in Britain. Royal Society Open Science, 12(1): 240555.https://royalsocietypublishing.org/doi/10.1098/rsos.240555

Support the show

Walter Kirn shares his perspective after sitting front row in the confirmation hearing of RFK Jr.

Find Walter on X: https://x.com/walterkirn
Find Walter at County Highway: https://www.countyhighway.com/

*****

Sponsors:

Brain.fm: intense music that boosts productivity. Unlock your brain’s full potential free for 30 days by going to brain.fm/DARKHORSE

Dose: Orange shot for your Liver health. Save 30% on your first months subscription at dosedaily.co/darkhorse

Fresh Pressed Olive Oil Club: Scrumptious & freshly harvested. Go to www.GetFreshDarkHorse.com to get a bottle of the best olive oil you’ve ever had for $1 shipping.


*****

Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/

Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.org/

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

Support the show

In this week’s episode, we discuss the Senate Confirmation Hearings of Bobby Kennedy Jr., in which the Democrats reveal a preference for anecdote over science, and work hard to maintain the status quo. As RFK seeks to Make America Healthy Again, he answers questions about infectious and chronic disease, SSRIs, Covid, farmers, autism, conspiracy theories, Medicaid and Medicare, and says with no equivocation: “I am not afraid of vested interests.” Also: Trump signs an Executive Order that will prevent the chemical and surgical mutilation of children; the new Press Secretary seems positively human; and the CIA admits the likelihood of a laboratory origin of Covid. Finally: check out Mike Nayna’s newest film, about Unity and Rescue the Republic.

*****

Our sponsors:

Brain.fm: intense music that boosts productivity. Unlock your brain’s full potential free for 30 days by going to http://brain.fm/DARKHORSE

Pique’s Nandaka: delicious mushroom, tea, and chocolate drink that provides all day energy. Get 20% off plus free frother+beaker at http://www.Piquelife.com/DARKHORSE

Fresh Pressed Olive Oil Club: Scrumptious & freshly harvested. Go to http://www.GetFreshDarkHorse.com to get a bottle of the best olive oil you’ve ever had for $1 shipping.

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

RFK Jr Senate Confirmation Hearing: https://www.youtube.com/watch?v=NeeC7nGm6cI

Protecting Children from Chemical and Surgical Mutilation: https://www.whitehouse.gov/presidential-actions/2025/01/protecting-children-from-chemical-and-surgical-mutilation/

CIA acknowledges likelihood of lab leak: https://apnews.com/article/covid-cia-trump-china-pandemic-lab-leak-9ab7e84c626fed68ca13c8d2e453dde1

A coalition of the Wyrd: https://www.youtube.com/watch?v=s-lsW5AalCc

Support the show

Bret Weinstein speaks with John McPherson on the subject of forensic accounting and whistleblowing. McPherson highlighting his concerns about the current financial landscape and the potential for another financial crisis.

*****

Sponsors:

MUD\WTR: Start your new morning ritual & get up to 43% off your @MUDWTR with DARKHORSE at  http://mudwtr.com/DARKHORSE #mudwtrpod

Dose: Save 30% on your first month of subscription by going to http://dosedaily.co/DARKHORSE or entering DARKHORSE at checkout.

*****

Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/

Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.org

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

*****

Mentioned in this episode:
Monthly Patreon Discussion: https://www.patreon.com/bretweinstein
The Big Short: https://amzn.to/3WzusnX (commission earned)
The Life Partners Case: https://www.wsj.com/articles/life-partners-trustee-files-recovery-lawsuits-1458316739
Whistle Blower Award Process: https://www.sec.gov/enforcement-litigation/whistleblower-program
Borrower Defense: https://studentaid.gov/borrower-defense 
Enron fake trading floor: https://www.theguardian.com/business/2002/feb/21/corporatefraud.enron1
Fair Rate Act: https://www.congress.gov/bill/115th-congress/senate-bill/186/text

Support the show

In this week’s episode, we discuss how it was to be in DC during Trump’s second Inauguration, and the MAHA ball. Then: a summary of Executive Orders: positive (e.g. freedom of speech, reality of biological sex, affirmative action, putting America first, securing our borders, establishing DOGE, J6 pardons, promoting beautiful architecture, and withdrawing from the WHO), negative (Gulf of America, the death penalty), and environmental (off-shore wind and natural gas, ANWR, fish and fires). Then: three reasons that Trump could become the best president we have had.

*****

Our sponsors:

CrowdHealth: Pay for healthcare with crowdfunding instead of insurance. It’s way better. Use code DarkHorse at http://JoinCrowdHealth.com to get 1st 3 months for $99/month.

Fresh Pressed Olive Oil Club: Scrumptious & freshly harvested. Go to http://www.GetFreshDarkHorse.com to get a bottle of the best olive oil you’ve ever had for $1 shipping.

ARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to http://www.tryarmra.com/DARKHORSE to get 15% off your first order.

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

Executive Orders by Trump: https://www.whitehouse.gov/presidential-actions/

Seed oil lobbyist becomes chief of staff at the USDA: https://x.com/repthomasmassie/status/1882459041089351735

Support the show

Bret Weinstein speaks with Dr. Toby Rogers on the subject of the economics of autism.

Find Toby Rogers on X at https://x.com/uTobian and on Substack at https://tobyrogers.substack.com.

*****

This episode is sponsored by:

Jolie: For your best skin & hair guaranteed head to http://jolieskinco.com/DARKHORSE to try it out for yourself with FREE shipping. 

*****

Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com 

Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.org

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

*****

Mentioned in this episode:

- Please see Toby Roger’s doctoral thesis, The Political Economy of Autism for links to studies mentioned https://ses.library.usyd.edu.au/bitstream/handle/2123/20198/Rogers_T_thesis.pdf 
- For example, the first autism prevalence study is linked in his References https://jamanetwork.com/journals/jamapsychiatry/article-abstract/490240 
- Hunter Gatherer's Guide https://amzn.to/40fPWqP (commission earned)
- The Moth in the Iron Lung https://amzn.to/3PHrHNb (commission earned)
- Bandom Health Project https://www.bandim.org
- Christine Stable Ben's Ted Talk https://youtu.be/_d8PNlXHJ48?si=5REOXsVpE7PrkTeI

Support the show

In this week’s episode, we continue our discussion of the Los Angeles Fires, sharing stories, analysis, and an apology from the owner of the LA Times, a publication which endorsed Karen Bass, LA’s current mayor. Even if diversity and inclusion have value, we need skill and experience more. Then: a new molecular technique reveals the extent to which mRNA shots move around the body and trigger the immune system to destroy transfected cells; this provides strong support for Bret’s years-old hypothesis that myocarditis and pericarditis are the result of T cell mediated destruction of cardiomyocytes. Finally: dung beetles, in life and in art. Who makes dung balls, who rolls dung balls, and why is it such a popular activity?

*****

Our sponsors:

Timeline: Accelerate the clearing of damaged mitochondria to improve strength and endurance: Go to http://www.timeline.com/darkhorse and use code darkhorse for 10% off your first order.

Caraway: Non-toxic, beautiful, light ceramic cookware. Save $150 on a cookware set over buying individual pieces, and get 10% off your order at http://Carawayhome.com/DarkHorse.

Fresh Pressed Olive Oil Club: Scrumptious & freshly harvested. Go to http://www.GetFreshDarkHorse.com to get a bottle of the best olive oil you’ve ever had for $1 shipping.

*****

Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

*****

Mentioned in this episode:

Cal Fire: https://www.fire.ca.gov

Remembering the Palisades: https://naturalselections.substack.com/p/remembering-the-palisades

The Morning Meeting w Patrick Soon-Shiong: https://www.youtube.com/live/QpolCpYGvw0?t=1092s

Luo et al 2025. Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning. Nat Biotechnol. https://www.nature.com/articles/s41587-024-02528-1.pdf

Sean Goddard Insects: https://seangoddardinsects.com

Reynolds & Byrne 2013. Alternate reproductive tactics in an African dung beetle, Circellium bacchus(Scarabeidae). Journal of Insect Behavior 26: 440-452. https://link.springer.com/article/10.1007/s10905-012-9365-1

Support the show