She was born and raised in South Florida, went to the University of Pennsylvania for her undergraduate years, Harvard University for her dental school, and then moved to southern California to complete a general dental residency.
In terms of dance, she started training in Indian classical dance, Bharatnatyam, from a young age. In college and dental school she was part of Penn Masti, a competitive Bollywood fusion dance team, and Aluminati, a national Bollywood fusion dance team. In 2020, Eshani started to dance on social media platforms such as Tiktok and Instagram. She is well known for combining shuffle footwork with various Indian dance styles and coining the term "DesiShuffle". In 2021, she co-founded DesiFuze, a dance company that she now travels and teaches with.