This podcast provides an overview of current and emerging data available in the treatment of EGFR Exon 20 Insertion Mutation Non-Small Cell Lung Cancer, including updates from ESMO 2023. Key takeaways:

- Review treatment options for EGFR Exon 20 Insertion Mutations in NSCLC

- Review updated clinical data from ELCC and ESMO 2023

- Gain an understanding around the management of treatment-related Adverse Events Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com

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Presenter:

Philip R. Muskin MD, MA, DLFAPA
Professor of Psychiatry
Columbia University Irving Medical Center
Senior Consultant in Consultation-Liaison Psychiatry
New York-Presbyterian Hospital
New York, NY

Chronic medical illnesses such as cancer are characterized by a notably increased prevalence of depression. Furthermore, several challenges may arise in managing the depression in these patients, given their anti-cancer regimens. Here, we present a short learning module that will help clinicians better recognize and diagnose patients with cancer who may also have depression, as well as develop treatment plans tailored to their concomitant anti-cancer regimens.

Follow along with the slideset located here:
https://bit.ly/3Auicb2 

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Presenter:

Hope S. Rugo MD
Professor of Medicine
University of California
San Francisco Comprehensive Cancer Center

TNBC comprises approximately 15% of newly diagnosed breast cancer cases and is defined by being estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor receptor 2-negative. This breast cancer subtype is very aggressive, with a median overall survival slightly greater than 1 year. Furthermore, treatment options are limited. New and innovative therapies are being evaluated in patients to improve their outcomes, including progression-free survival and time to deterioration in health-related quality of life. Here, we present an expert-led review on current standards of care, as well as novel and emerging treatment regimens that are in the pipeline for approval by the United States Food and Drug Administration and/or under investigation.

Follow along with the slideset located here:
https://bit.ly/3krD3Gj 

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Presenter:

Gail J. Roboz MD
Professor of Medicine
Director, Clinical and Translational Leukemia Program
Weill Medical College of Cornell University
New York-Presbyterian Hospital
New York, New York, United States

This brief program will begin with a review of NCCN Guidelines® Recommendations for the treatment of AML in individuals 60 years of age or older. Next, the results of the BRIGHT AML 1003 trial comparing glasdegib + LDAC to LDAC alone, the VIALE-A trial comparing venetoclax + azacitidine vs azacitidine alone, and a comparison of CPX-351 vs standard of care cytarabine + daunorubicin (7 + 3 regimen) for induction and consolidation, will be reviewed. The faculty will discuss FLT3 and IDH inhibitor approvals for AML, IDK differentiation syndrome, and measuring MRD in AML. Finally, results of a trial examining oral azacitidine and a meta-analysis of 5 trials examining gemtuzumab ozogamicin will be reviewed.https://www.clinical-care.org/resource-center-details/using-available-evidence-and-guidelines-for-managing-an-evolving-aml-treatment-paradigm

Follow along with the slideset located here:
https://bit.ly/3lJNHYC  

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