In this Dementia Researcher Podcast episode, Dr Aitana Sogorb Esteve hosts a discussion with Dr Charlie Arber and Sam Crawford from University College London, discussing their work on familial British dementia (FBD), a rare form of dementia affecting only a handful of families. The discussion explores the latest findings from human stem cell models that are helping researchers understand FBD’s unique genetic and pathological features, and how that can inform a wider understanding of familial Alzheimer’s Disease.

Topics covered include:

- Genetic causes and symptoms of familial British dementia

- Use of stem cell models, particularly iPSCs, to study FBD in the lab

- Potential biomarkers and implications for therapeutic research

- How funding from the Race Against Dementia Ignition Fund is supporting advancements in rare dementia research

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Full biographies on all our guests and a transcript can be found on our website: https://www.dementiaresearcher.nihr.ac.uk

Find out more at Race Against Dementia:

https://www.raceagainstdementia.com/

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This podcast is brought to you by University College London / UCLH NIHR Biomedical Research Centre in association with Alzheimer’s Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia who we thank for their ongoing support.

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