Decoding Healthcare Research

Decoding Healthcare Research

By Agora ProjectHealth & Fitness
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Decoding Healthcare Research episodes

  • Understanding Aging: The Science of Healthy Aging

    In this episode, we discuss aging as a natural process that everyone experiences, emphasizing that it doesn't necessarily have to be detrimental. On the contrary, by understanding the factors behind it, we can make decisions to positively influence this process. Our guest, Tamas Fulop, MD, PhD, is a professor of medicine and geriatrics and a senior researcher at the Research Center on Aging, University of Sherbrooke, Québec, Canada.

    Reference: Fulop T, Larbi A, Pawelec G, Khalil A, Cohen AA, Hirokawa K, Witkowski JM, Franceschi C. Immunology of Aging: the Birth of Inflammaging. Clin Rev Allergy Immunol. 2023 Apr;64(2):109-122. doi: 10.1007/s12016-021-08899-6. Epub 2021 Sep 18. PMID: 34536213; PMCID: PMC8449217.


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    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    43 min
  • Is sleep regularity more important than duration for our health?

    In this episode, we are going to analyze the effect of sleeping at regular times on our long-term health. I hope this information is useful to you.

    I invite you to leave your questions, opinions, and suggestions in the comments, and to share so that we can all continue learning together.
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    Reference: Windred DP, Burns AC, Lane JM, Saxena R, Rutter MK, Cain SW, Phillips AJK. Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study. Sleep. 2024 Jan 11;47(1)
    . doi: 10.1093/sleep/zsad253. PMID: 37738616; PMCID: PMC10782501.
    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    4 min
  • Precision Medicine in Oncology: Cutting-Edge Techniques Explained.

    In this episode, we have two very special guests who are going to shed light on a developing field: the genotyping and analysis of circulating DNA in the detection and follow-up of cancer. This is part of the technologies in precision medicine that could contribute to improving the effectiveness of treatments. We are joined by Dr. Lilian Siu, a senior medical oncologist at the Princess Margaret Cancer Centre since 1998, and a Professor of Medicine at the University of Toronto since 2009. She is the Director of the Phase I Program and Co-Director of the Bras and Family Drug Development Program at the Princess Margaret Cancer Centre, and holds the BMO Chair in Precision Genomics (2016-2026). Dr. Siu’s major research focus is in the area of new anticancer drug development, particularly with respect to phase I trials and head and neck malignancies.

    Our other guest, Dr. David Cescon, is a breast medical oncologist and clinician-scientist at the Princess Margaret Cancer Centre. His research integrates laboratory and clinical studies, focused on identifying breast cancer therapeutic vulnerabilities and determinants of drug response and resistance. Leveraging pre-clinical model platforms and genomic tools, including liquid biopsy, the overarching goal of his work is to advance the delivery of precision therapy to improve breast cancer outcomes through both the prevention and treatment of metastatic disease.
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    Reference: Cescon DW, Bratman SV, Chan SM, Siu LL. Circulating tumor DNA and liquid biopsy in oncology. Nat Cancer. 2020 Mar;1(3):276-290. doi: 10.1038/s43018-020-0043-5. Epub 2020 Mar 20. PMID: 35122035.

    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    44 min
  • Does apple cider vinegar help with weight loss and metabolic control?

    In this episode, we analyze the results of a study that evaluated the effects of consuming different doses of apple cider vinegar on the weight of adolescents and adults. I hope this information is useful to you.


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    Reference: Abou-Khalil R, Andary J, El-Hayek E. Apple cider vinegar for weight management in Lebanese adolescents and young adults with overweight and obesity: a randomised, double-blind, placebo-controlled study. BMJ Nutr Prev Health. 2024 Mar 12;7(1):61-67. doi: 10.1136/bmjnph-2023-000823. PMID: 38966098; PMCID: PMC11221284.


    Disclosure: 

    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    4 min
  • Is mTOR the Key to Anti-Aging and Longevity?

    In this episode, we have Dr. Dudley Lamming, PhD, Associate Professor and Researcher at the Department of Medicine, Endocrinology at the University of Wisconsin-Madison. We will talk about aging and specifically about a molecule that has been gaining interest in the scientific field: mTOR. We’ll discuss its importance, how it is regulated, and much more. Additionally, we will explore the effects of Rapamycin and its potential pharmacological applications. Join us for an insightful discussion! Dr. Lamming’s research focuses on understanding how nutrient-responsive signaling pathways can be harnessed to promote health and longevity.

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    Reference: Mannick JB, Lamming DW. Targeting the biology of aging with mTOR inhibitors. Nat Aging. 2023 Jun;3(6):642-660. doi: 10.1038/s43587-023-00416-y. Epub 2023 May 4. PMID: 37142830; PMCID: PMC10330278.


    Disclosure:

    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    37 min
  • Can Better Sleep Help You Lose Weight?

    In this episode, we analyze the results of a study that aimed to evaluate the impact of sleep quality on weight and energy balance in overweight individuals. I hope you find this information useful.

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    Reference: Tasali E, Wroblewski K, Kahn E, Kilkus J, Schoeller DA. Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings: A Randomized Clinical Trial. JAMA Intern Med. 2022 Apr 1;182(4):365-374. doi: 10.1001/jamainternmed.2021.8098. PMID: 35129580; PMCID: PMC8822469.

    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    5 min
  • Understanding Sugar's Impact on Your Body.

    In this episode, we will talk about glucotypes, sugar, glycemia, and the impact of your body's capacity to properly respond to the sugar you eat in order to maintain a well-functioning metabolism. Our guest, Dr. Snyder, Chair of the Department of Genetics and Director of the Center for Genomics and Personalized Medicine at Stanford University, will shed light on the topic. I hope you enjoy the episode and find it useful. In the study we used as a base for the conversation, they explain how interindividual variability in glycemic responses to standardized meals highlights the personal nature of glucose regulation. Through extensive phenotyping, we developed a model for identifying potential metabolic differences.

    Reference:
    Hall H, Perelman D, Breschi A, Limcaoco P, Kellogg R, McLaughlin T, Snyder M. Glucotypes reveal new patterns of glucose dysregulation. PLoS Biol. 2018 Jul 24;16(7):e2005143. doi: 10.1371/journal.pbio.2005143. PMID: 30040822; PMCID: PMC6057684.

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    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    36 min
  • Does the time you EXERCISE affect the quality of your SLEEP?

    In this episode, we analyze the results of a study that focused on determining whether the time of day when exercise is performed affects sleep quality or the ability to fall asleep.

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    Reference:
    -Goldberg M, Pairot de Fontenay B, Blache Y, Debarnot U. Effects of morning and evening physical exercise on subjective and objective sleep quality: an ecological study. J Sleep Res. 2024 Feb;33(1):e13996. doi: 10.1111/jsr.13996. Epub 2023 Jul 10. PMID: 37431176.
    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    5 min
  • What can we LEARN FOR OUR HEALTH from people who live 100 years or more?

    In this episode, we discuss the results of a paper that analyzes the health characteristics of people who live longer and healthier lives. Our guests, Dr. Karin Modig, PhD, and Dr. Shunsuke Murata, researchers at the Karolinska Institute in Sweden, explain their findings. Dr. Modig's main research focuses on comprehensively elucidating the determinants of increased longevity and assessing the quality of extended lifespan. Dr. Murata's research focuses on the prevention and management of disease and disability in older adults.

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    Reference: Murata S, Ebeling M, Meyer AC, Schmidt-Mende K, Hammar N, Modig K. Blood biomarker profiles and exceptional longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort. Geroscience. 2024 Apr;46(2):1693-1702. doi: 10.1007/s11357-023-00936-w. Epub 2023 Sep 19. Erratum in: Geroscience. 2024 Apr;46(2):2793-2794. doi: 10.1007/s11357-023-00996-y. PMID: 37726432; PMCID: PMC10828184.

    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

    34 min
  • The impact of SLEEP TIME on our health

    In this flash episode, we analyze the results of a study that evaluated the impact of sleep hours on our health markers. I hope this information is useful to you.

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    Reference: Addo PNO, Mundagowa PT, Zhao L, Kanyangarara M, Brown MJ, Liu J. Associations between sleep duration, sleep disturbance and cardiovascular disease biomarkers among adults in the United States. BMC Public Health. 2024 Apr 2;24(1):947. doi: 10.1186/s12889-024-18381-5. PMID: 38566084; PMCID: PMC10985959.
    Disclosure:
    The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

    8 min

About Decoding Healthcare Research

From the publisher's feed

Welcome to "Decoding Healthcare Research", a podcast by Agora Project. Join us as we delve into the behind-the-scenes world of groundbreaking research and the dynamic healthcare industry, interviewing…