Vishal Doshi, chairman and CEO of AUM Biosicences, discusses the development of resistance in cancers, the case of combining precision therapies with immunotherapies, and why he believes we can transform cancer from a deadly condition to a chronic disease.

Developing Targeted Therapies to Address Resistance in Cancer

The Bio Report podcast, hosted by award-winning journalist Daniel Levine, focuses on the intersection of biotechnology with business, science, and policy.

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Life Sciences

John Lewis, founder and CEO of Aegis Life, discusses the global need to address infectious diseases, the company’s platform technology, and how it is leveraging that to address the barriers to the delivery of vaccines and antibody therapies in developing economies.

How Solving a Problem with Genetic Medicines May Solve Another with Infectious Diseases

Jay Hartenbach, chief operating officer of Diakonos Oncology, discusses the company’s dendritic cell cancer vaccine technology, how it works, and why its lead indication is an aggressive form of brain cancer.

Boosting the Power of Dendritic Cancer Vaccines

James Porter, CEO of Nuvalent, discusses how the company designs drugs that address the challenges of both kinase resistance and selectivity, its pipeline in development, and why it’s critical that its experimental therapy for non-small cell lung cancer can penetrate the brain.

Overcoming Resistance in Cancer with Chemistry

Bobby Azamian, CEO of Tarsus, discusses Lyme disease, the case for the company’s experimental prophylactic drug TP-05, and why you may already have been using a form of the drug to protect a four-legged member of your household.

Teaching an Old Drug a New Trick to Prevent Lyme Disease

Jason Bock, CEO of CMTC, the joint venture between Resilience and MD Anderson Cancer Center, discusses the emerging area of TIL therapies, the significance of the first approved therapy in the class, and how they may address existing limitations of CAR-T therapies.

Developing Targeted Therapies to Address Resistance in Cancer

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