The Curbsiders Internal Medicine Podcast

#96 Diabetes: A1C targets & ACP guidelines controversy

05.21.2018 - By The Curbsiders Internal Medicine PodcastPlay

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Get schooled on hemoglobin a1c targets in type 2 diabetes mellitus by American College of Physicians guidelines coauthor, Devan Kansagara MD MCR, Associate Professor of Medicine, Oregon Health Sciences University. We summarize outcomes from the landmark diabetes trials (ACCORD, ADVANCE, VADT, UKPDS 33 & 34), how a1c targets effect microvascular and macrovascular events, estimating life expectancy, and how to personalize diabetes control for your patients. We’re proud to announce our new partnership with the ACP to provide free CME credit and MOC points on select episodes of The Curbsiders. ACP members can visit acponline.org to redeem free CME/MOC credit.

Full show notes available at http://thecurbsiders.com/podcast

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Credits:

Written, produced, and edited by: Matthew Watto MD.

Hosts: Stuart Brigham MD, Paul Williams MD, Matthew Watto MD.

Guest: Devan Kansagara MD, MCR

Time Stamps

00:00 Announcement

00:48 Disclaimer and intro

03:11 Getting to know our guest: one liner, book recommendation, mentorship

06:50 How and why did ACP write their guidance statement on diabetes, A1C targets

09:18 Landmark trials in type 2 diabetes

11:36 Does tight control prevent micro or macrovascular complications

13:20 Trials of newer agents like SGLT2i, GLP-1 and DPP4i

14:33 How do ACP’s guidelines differ from other published guidelines

17:20 Quick recap of landmark trial findings

22:24 Personalizing glycemic control

24:30 Controversy over an A1C goal of 7-8%

28:05 Clinical inertia

30:26 Legacy effect and metabolic memory

34:00 Deintensifying therapy

38:29 Life expectancy and comorbid conditions

43:15 Performance measures in diabetes

44:42 Take-home points

46:30 The Curbsiders recap and give some closing remarks

49:13 Outro 

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