Russ Branzell, President and CEO of CHIME, welcomes Theresa Meadows, Chief Information Officer in Residence at symplr, for an in-depth conversation on the evolving role of the healthcare CIO. Drawing on decades of leadership experience and a unique vantage point across health systems, Theresa explores how digital health leaders are expanding beyond traditional IT responsibilities to become strategic business partners. Together, they examine the realities of leading through complexity, the importance of enterprise-wide perspective, and how today’s CIOs are driving alignment, simplification, and lasting organizational impact.

Key Takeaways:

1. How the role of the healthcare CIO is evolving from technology steward to strategic business leader amid rising industry pressures and complexities.

2. The growing importance of business acumen and how digital health leaders can strengthen their influence on organizational strategy.

3. Where complexity is creating the greatest friction in healthcare today and how simplification strategies like integration and standardization can unlock better outcomes.

4. The role of leadership, mentorship, and community stewardship in shaping the future of digital health and supporting the next generation of CIOs.

In this episode, Russ Branzell, President and CEO of CHIME, is joined by Lyle McMillin, Associate Vice President of Product Management at Hyland, for a dynamic discussion on turning digital health ambition into measurable performance. The conversation examines how healthcare leaders translate innovation — particularly in cloud, AI, and enterprise imaging — into scalable, real-world use and impact. Lyle shares frontline insights on what’s driving meaningful progress today, what’s getting lost in the noise, and how organizations can build trust while navigating complex digital transformation decisions.

Key Takeaways:

1. What determines whether AI, cloud, and automation initiatives scale effectively across clinical and operational environments.

2. The gap between hype and reality in digital health, including which trends are truly delivering results.

3. Practical strategies for scaling digital solutions across fragmented systems, workflows, and organizational cultures.

4. How leaders can evaluate emerging technologies and make confident, future-focused investments that deliver long-term value.

Russ Branzell, President and CEO of CHIME, welcomes Cletis Earle, Field CTO for Healthcare at Citrix, for a thoughtful discussion on what it takes to build resilient, high-performing digital health environments. Drawing on his experience as both a health system executive and technology strategist, Cletis shares practical insight into how organizations can better align technology investments with clinical and operational priorities. Together, they explore how healthcare leaders are modernizing legacy systems, improving workflows, and enabling secure, seamless access to critical data.

Key Takeaways:

1. How leading health systems are unlocking measurable value from technology investments to improve care delivery and workforce efficiency.

2. Practical approaches to modernizing applications and workflows in ways that enhance both caregiver experience and patient outcomes.

3. Strategies for balancing security, compliance, and frictionless access to clinical systems in distributed care environments.

4. The leadership mindset required to build resilient digital infrastructures while mentoring and developing the next generation of healthcare IT leaders.

Russ Branzell, President and CEO of CHIME, sits down with Adam Gale, Founder and CEO of KLAS Research, and Dr. Richa Gupta, Vice President of Care Transformation at Ambience Healthcare to discuss the future of artificial intelligence in healthcare operations. As recipients of the CHIME and KLAS Trailblazer Award, Ambience Healthcare represents a new generation of technology companies recognized not just for innovation, but for measurable outcomes inside health systems. Together, the leaders explore how ambient AI is evolving beyond documentation support into broader clinical and operational intelligence—impacting coding accuracy, compliance, and revenue integrity.

Key Takeaways:

1. How health systems are redefining AI maturity as they move from experimentation to enterprise-scale deployment across clinical and operational workflows.

2. Why ambient AI is expanding beyond clinician documentation to influence coding accuracy, compliance, and revenue integrity across health systems.

3. The organizational conditions required to successfully scale AI initiatives, including workflow integration, leadership alignment, and clinician adoption.

4. What separates high-performing healthcare AI vendors from early-stage solutions that struggle to move beyond pilot programs.

5. How digital health leaders can balance innovation, governance, and trust as artificial intelligence becomes embedded in core healthcare operations.

Russ Branzell, President and CEO of CHIME, welcomes Dr. Jacob Strand, Chair of Palliative Care at Mayo Clinic in Rochester and Enterprise Chair for the Palliative Care Specialty Council to the show for a conversation that challenges how health systems think about care delivery for patients with serious illness. Together, they examine how digital health leaders can move beyond traditional models of specialty care to build scalable systems that connect data, clinical insight, and operational accountability, ensuring the right care reaches the right patient at the right time.

1. How predictive analytics can help health systems identify patients with serious and complex illness earlier, enabling more proactive and coordinated care.

2. Why designing scalable clinical workflows is essential for improving outcomes and managing rising healthcare complexity.

3. The role digital health leaders play in connecting data, clinical teams, and operational strategy to support more patient-centered care models.

4. Practical ways health systems can use data and digital tools to align care delivery with what matters most to patients and families facing serious illness.

5. Lessons from Mayo Clinic’s approach to integrating palliative care insights across the enterprise to support clinicians and improve patient experience.

In this episode, Russ Branzell, President and CEO of CHIME, speaks with PV SubbaRao, President of Healthcare Provider at NTT DATA, about what it truly takes to operationalize AI for lasting transformation. Together, they discuss the leadership decisions, governance structures, and workflow redesign required to scale AI responsibly while driving measurable improvements in financial sustainability, operational resilience, and care delivery.

Key Takeaways:

1. Why AI represents a structural shift in healthcare operations and the signals that indicate organizations have reached a true transformation inflection point.

2. The governance, data architecture, and investment decisions required to successfully move AI initiatives from pilot programs to enterprise-scale deployment.

3. How leading organizations are redesigning clinical and operational workflows, roles, and decision-making structures as AI becomes embedded into everyday work.

4. What distinguishes true AI-enabled revenue cycle transformation from traditional automation efforts and how it can support long-term financial sustainability.

5. The leadership, cultural shifts, and performance metrics required to align the C-suite and measure the real impact of AI-driven transformation across the enterprise.

Russ Branzell, President and CEO of CHIME, sits down with Abdul Shaikh, Global Leader for Digital Health at Amazon Web Services, for a forward-looking conversation on what it takes to scale artificial intelligence responsibly across healthcare. Drawing from global experience advising health systems, payors, and governments, Dr. Shaikh shares insights on how leaders can move from AI pilots to accountable, enterprise-level impact while ensuring technology adoption strengthens both care delivery and confidence in the health system.

Key Takeaways:

1. How to recognize the moment AI shifts from isolated innovation projects to enterprise-wide operational exposure requiring formal governance and executive oversight.

2. The foundational infrastructure, cloud architecture, interoperability, and cybersecurity capabilities needed to scale AI safely across health systems.

3. What true workforce readiness looks like as AI reshapes clinical documentation, operational workflows, and decision-making responsibilities.

4. The critical questions executives and boards should ask about AI performance, bias, transparency, and long-term accountability.

5. Why patient trust is the ultimate measure of success for AI in healthcare—and how leaders can ensure transparency and confidence as AI becomes embedded in the care experience.

Derrek Hallock, Senior Vice President of Growth at SHI Healthcare, joins Russ Branzell, President and CEO of CHIME, to explore what it takes to scale digital health with intention in today’s healthcare ecosystem. Calling on his deep experience in operational leadership, process optimization, and building high-performing teams, Derrek shares his approach to accelerating growth across teams and healthcare systems.

Throughout their discussion, they examine how healthcare organizations can responsibly scale technology infrastructure, navigate innovation such as generative AI and next-generation security, and leverage digital health solutions to expand access, advance equity, and improve outcomes across diverse care settings.

Key Takeaways:

1. How healthcare leaders can define and pursue growth beyond revenue, focusing on operational efficiency, provider impact, and patient outcomes.

2. Key challenges and opportunities health systems face when scaling digital infrastructure, including AI adoption, hybrid cloud environments, and next-generation security frameworks.

3. Practical guidance for prioritizing innovation so technology investments deliver sustainable value, measurable outcomes, and long-term transformation.

4. Leadership principles that support sustainable growth, including transparent communication, a “no surprises” management style, and a culture of continuous learning and accountability.

5. How digital health strategies can expand access to care, particularly for rural and underserved communities, while aligning with provider priorities around cost, scalability, and resilience.

Russ Branzell, President and CEO of CHIME, sits down with Melissa Ursi, Chief Executive Officer of Quoris, for a timely conversation on leading with intention during periods of organizational and industry transformation. With more than 20 years of experience across healthcare IT and executive leadership, Melissa shares how Quoris is navigating its next chapter, balancing evolution with the trust, culture, and expertise that leaders and teams rely on.

Together, they explore what it takes to sustain alignment through change, translate technology strategy into operational results, and develop future-ready leaders in a healthcare environment defined by complexity, scale, and constant evolution.

Key Takeaways:

1. How healthcare organizations can evolve their brand, structure, and strategy without disrupting the culture and trust that underpin long-term client and team relationships.

2. Practical strategies for maintaining clarity, consistency, and shared purpose across distributed teams without sacrificing flexibility.

3. Where healthcare organizations most often struggle to turn technology investments into measurable outcomes and how to close the gap between strategy and execution.

4. What digital health leaders should prioritize beyond implementation to drive long-term adoption, optimization, and sustained value from technology initiatives.

5. The skills, mindsets, and leadership behaviors that will define the next generation of healthcare IT leaders and how today’s executives can intentionally develop emerging talent.

What Keeps You Up at Night? – Tales from the Digital Frontier 

Russ Branzell, President and CEO of CHIME, sits down with Tim Lankes, Vice President of Healthcare at Rackspace, for a candid conversation on the realities behind cloud modernization in healthcare. Drawing on decades of experience leading large-scale healthcare technology and services initiatives, Tim shares how organizations are balancing innovation with security, cost, and continuity of care amid increasing regulatory and operational pressures.

Throughout their discussion, they explore what’s driving successful cloud and multicloud strategies today, including separating hype from practical value in AI adoption to scaling pilots into enterprise-wide impact.

Key Takeaways:

1. How digital health leaders can modernize infrastructure, strengthen data accessibility, and align technology with human adoption to deliver outcomes that matter.

2. Where multicloud strategies are creating the greatest operational value and what often gets overlooked.

3. What it takes to move cloud and AI initiatives from pilot projects to sustained, enterprise-wide platforms.

4. How AI is delivering practical benefits today by optimizing cloud environments and supporting data-driven decision-making.