Will Dyer references Matthew 6:10 and Luke 22:42 to emphasize the importance of surrendering to God's will. The sermon is based on Pete Greig's book, How to Pray: A Simple Guide for Normal People, which outlines a framework for prayer: pause, rejoice, ask, and yield. Will Dyer highlights the significance of mutuality in relationships, including with God, emphasizing that prayer is not just about asking but also listening. They discuss various ways to hear God's voice, such as through Scripture, dreams, visions, counsel, common sense, personal reflection, and action. The sermon encourages the congregation to develop a deeper prayer life by being still, reading the Bible daily, and listening for God's guidance in everyday moments. The message concludes with a call to embrace prayer as a living relationship with a loving God, ending with the affirmation, "Amen. Let it be so."