Explores current research on the actions and therapeutic potential of these compounds. Much of the text discusses the classification and characterization of dopamine receptor subtypes—specifically D-1 and D-2—based on their pharmacological actions and biochemical properties in both the central nervous system (CNS) and peripheral tissues, such as the cardiovascular system and the gastrointestinal tract. Several sections are dedicated to detailing the structure-activity relationships (SAR) of various dopamine agonists and antagonists, including ergots, and their clinical applications in neurological disorders like Parkinson's disease, as well as in treating conditions like shock and hypertension via cardiovascular effects. The content also addresses the physiological roles of dopamine in the periphery, including its function in aldosterone secretion and as a potential neurotransmitter.
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