Medicine Made Simple episodes:

• January 14, 2026Cunningham’s Manual Of Practical Anatomy: Thorax And Abdomen

  Focusing on the thorax, abdomen, and pelvis/perineum. The material includes forewords and prefaces for the sixteenth edition of Cunningham’s Manual of Practical Anatomy, highlighting the book's long history, revisions for modern medical curricula, and dedication to practical dissection. Detailed anatomical descriptions are given for the skeletal framework of the trunk—such as the ribs, vertebrae (thoracic and lumbar), and pelvis—along with discussions of musculature, neurovasculature, and viscera. Specifically, the text explains the structures of the chest wall, lungs, abdominal organs (like the spleen, liver, duodenum, and pancreas), and the anatomy of the male and female pelvis and perineum, often utilizing dissection instructions and clinical applications to enhance learning.
  
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• January 13, 2026Kadasne’s Textbook Of Anatomy (Clinically Oriented): Thorax, Abdomen And Pelvis

  A detailed medical resource covering the anatomical and clinical aspects of various body regions and organs, including the osteology of the torso, the pleura and lungs, the heart and blood vessels, and structures within the abdominal cavity (such as the stomach, spleen, liver, pancreas, and kidneys). The excerpts also examine the anatomy of the male perineum and urinary tract, illustrating complex systems like the male urethra and the internal iliac artery, often including clinical notes and diagrams for educational clarity.
  
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• January 12, 2026Kadasne’s Textbook Of Anatomy (Clinically Oriented): Upper And Lower Extremities

  Focusing extensively on the upper and lower extremities. The content encompasses a detailed osteology of the limbs, describing bones like the femur, patella, and carpals, alongside the classification and characteristics of different joints, such as fibrous, cartilaginous, and synovial types. Furthermore, the text thoroughly examines the muscles, nerves, and vessels of these regions, including specifics on the brachial plexus, axillary artery, and the anatomy of the foot's arches. A key theme throughout the material is the integration of clinical and surgical relevance to anatomical descriptions, highlighting conditions like fractures, nerve injuries, and joint disorders associated with the structures of the limbs.
  
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• January 11, 2026Adult CNS Radiation Oncology: Principles and Practice

  A comprehensive overview of radiation oncology for central nervous system (CNS) tumors, focusing heavily on diagnosis, grading, and multimodal treatment strategies. Several types of tumors are discussed, including meningiomas, craniopharyngiomas, various gliomas, spinal cord tumors, and metastatic brain disease, often referencing the WHO grading criteria and prognostic factors like the extent of surgical resection. A significant portion of the text details radiation techniques such as Stereotactic Radiosurgery (SRS), Intensity-Modulated Radiation Therapy (IMRT), and Proton Beam Therapy, comparing their application, dose prescriptions, and the critical importance of Organ-at-Risk (OAR) dose constraints to manage potential radiation toxicity like radionecrosis and neurocognitive decline. Ultimately, the material highlights the need for precise planning and sophisticated delivery systems to optimize tumor control while minimizing long-term patient morbidity.
  
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• January 10, 2026Advanced Skin Cancer: A Case-Based Approach

  Focuses on a case-based approach to diagnosing and managing various advanced cutaneous malignancies. The sources are heavily focused on melanoma, discussing its subtypes, staging systems (like AJCC and BWH for cSCC), and treatment protocols, including surgery (WLE, Mohs, SLNB), radiotherapy (TSEBT, focal RT), and systemic therapies such as immunotherapy (PD-1 inhibitors, anti-CTLA-4 agents like nivolumab and ipilimumab) and targeted therapy (BRAF/MEK and hedgehog pathway inhibitors like vismodegib/sonidegib). The text thoroughly examines the management of different cancers, including Cutaneous Lymphoma (MF, PC-ALCL, PCFCL, PC-DLBCL), Kaposi’s Sarcoma (AIDS-associated, iatrogenic), Basal Cell Carcinoma (laBCC, BCNS), Dermatofibrosarcoma Protuberans (DFSP), and Merkel Cell Carcinoma (MCC), often detailing efficacy, side effects, and resistance mechanisms associated with specific drugs. Additionally, it highlights the importance of the multidisciplinary tumor board and specific diagnostic tools, such as the MCPyV oncoprotein antibody test for MCC surveillance.
  
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• January 09, 2026An Atlas of Gynecologic Oncology: Investigation and Surgery

  A comprehensive look at surgical management for various pelvic cancers, emphasizing techniques, anatomy, and patient care. Several sections detail radical surgical procedures for cervical and other cancers, including abdominal and vaginal hysterectomy and trachelectomy, with specific discussions on laparoscopy and the use of the LEEP/LETZ for cone biopsy. The text also covers critical perioperative considerations, such as the prophylaxis and treatment of thromboembolic disease and the prevention of blood-borne infection using universal precautions. Finally, it addresses the management of complications like fistula repair and the psychological aspects of care through the "four-cusp" approach to doctor-patient communication.
  
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• January 08, 2026Pathology: Basic Pathology, Systemic Pathology

  Focusing on a broad range of human pathology. The content is organized into chapters covering multiple organ systems, including detailed information on female and male reproductive pathology, such as disorders of the uterus, ovaries, and testes, and sexually transmitted diseases. Significant portions are dedicated to endocrine pathology, discussing the pituitary, thyroid, adrenals, and the endocrine pancreas (diabetes and islet cell tumors). Further chapters summarize the pathology of the cardiovascular system (arteriosclerosis and hyperlipoproteinemia), the renal system (glomerular disorders, tubular necrosis, and tumors), the central and peripheral nervous systems (meningitis, multiple sclerosis, and various tumors), and musculoskeletal and connective tissue disorders (collagen disorders, joint pathology, and muscle diseases).
  
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• January 07, 2026Physiology

  Covering major human organ systems and fundamental cellular mechanisms. The content focuses extensively on endocrinology, detailing the regulation and actions of hormones from the pituitary, adrenal, pancreas, and thyroid glands, including discussions on diabetes mellitus and calcium and phosphate homeostasis. Other core physiological topics addressed include gastrointestinal function, such as gastric and intestinal motility and secretions, and respiratory mechanics, covering airway resistance, ventilation, and oxygen transport. Additionally, the sources examine membrane physiology, explaining concepts like transport, diffusion, and action potentials in both neurons and cardiac muscle cells, along with aspects of renal physiology and the control of systemic blood pressure.
  
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• January 06, 2026Berek & Hacker’s Gynecologic Oncology

  A comprehensive reference tool for healthcare professionals focusing on gynecologic cancers. The text emphasizes the intersection of art and science in medical practice, particularly within the subspecialty of gynecologic oncology, acknowledging rapid advancements in areas like molecular biology and medical imaging. Significant portions of the material discuss the molecular basis of cancer, detailing concepts such as oncogenes, tumor suppressor genes like TP53, DNA repair mechanisms like Mismatch Repair (MMR), and cellular processes like apoptosis and the cell cycle. Furthermore, the text thoroughly addresses the clinical management of specific gynecologic cancers, including discussions on cervical, ovarian, and endometrial malignancies, covering topics like chemotherapy protocols, radiation therapy techniques (including brachytherapy), and surgical strategies for different cancer stages. The material also incorporates elements of biostatistics and epidemiology, contrasting different study designs and discussing the principles of statistical inference related to cancer risk and treatment effectiveness.
  
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• January 05, 2026Pathology: Basic Pathology, Systemic Pathology

  Covering Basic Pathology in Chapters one through nine. The chapters examine fundamental pathological processes, including cellular pathophysiology focusing on hypoxia, cell injury, and necrosis, followed by inflammation and tissue repair with sections detailing acute and chronic inflammation, and wound healing. Subsequent chapters address hemodynamics, covering processes like hemostasis, thrombosis, embolism, and shock, as well as an extensive overview of neoplasia (cancer) including carcinogenesis mechanisms and tumor classification. Finally, the text explores different types of red blood cell pathology (anemia) and the characteristics of various lymphoid pathologies, such as Hodgkin and non-Hodgkin lymphomas and plasma cell neoplasms.
  
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