Medicine Made Simple episodes:

• January 05, 2026Pathology: Basic Pathology, Systemic Pathology

  Covering Basic Pathology in Chapters one through nine. The chapters examine fundamental pathological processes, including cellular pathophysiology focusing on hypoxia, cell injury, and necrosis, followed by inflammation and tissue repair with sections detailing acute and chronic inflammation, and wound healing. Subsequent chapters address hemodynamics, covering processes like hemostasis, thrombosis, embolism, and shock, as well as an extensive overview of neoplasia (cancer) including carcinogenesis mechanisms and tumor classification. Finally, the text explores different types of red blood cell pathology (anemia) and the characteristics of various lymphoid pathologies, such as Hodgkin and non-Hodgkin lymphomas and plasma cell neoplasms.
  
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• January 04, 2026Immunology, Microbiology

  Focusing on Immunology and Microbiology. The content covers foundational immunological concepts like inflammation, antigen presentation, and B and T lymphocyte function, including the structure and mechanisms of B-cell and T-cell receptors. A significant portion addresses the pathogenesis and classification of infectious agents, such as viruses, bacteria, and parasites, detailing their characteristics and mechanisms of action, including antibiotic resistance and genetic exchange in bacteria. Furthermore, the material explores clinical applications of immunology, featuring chapters on diagnostic medicine (like EIA, Western Blot, and FACS), transplantation immunology, and various hypersensitivity and immunodeficiency disorders, often presenting this information through tables, figures, and clinical case examples.
  
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• January 03, 2026Biochemistry, Genetics

  A detailed academic overview of core biological processes, including DNA replication, gene expression (transcription and translation), and protein fate (folding, modification, and targeting). Furthermore, they explore the complexity of mutations and DNA repair mechanisms, touch upon molecular biology techniques (such as PCR and blotting), and conclude with an examination of thermodynamics and various metabolic pathways, including those related to nucleotides, nitrogen, and lipids. Finally, the material addresses human genetics concepts, such as inheritance patterns, gene mapping, and the principles of gene therapy and transgenic animals.
  
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• January 02, 2026Atlas of Head and Neck Surgery

  A comprehensive surgical reference for procedures across the head and neck region. The text provides a highly detailed, step-by-step breakdown of numerous operations, including techniques for laryngoscopy, esophagoscopy, neck dissections, and tumor resections in areas like the larynx, thyroid, and skull base. The editors explain their approach of soliciting expert authors to delineate procedures as if instructing a novice, frequently including editorial commentary that offers alternative techniques, specialized preferences, and crucial surgical warnings from various specialists. Overall, the source serves as an in-depth, multi-contributor guide to the technical execution of complex head and neck surgical procedures and reconstructive options.
  
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• January 01, 2026Atlas of Cardiac Surgical Techniques

  A detailed look into various cardiothoracic surgical procedures. The content offers step-by-step guidance on techniques, including coronary artery bypass grafting via traditional and minimally invasive approaches, and open-heart valve and aortic procedures. Throughout the sections, surgical anatomy, operative steps, and pearls and pitfalls are discussed for surgeons, residents, and medical students preparing for complex cases like postinfarction ventricular septal defect repair, aortic valve replacement, and heart transplantation. Additionally, the excerpts highlight the latest techniques in endovascular stent grafting and the use of ventricular assist devices, emphasizing the continually evolving nature of cardiac surgery.
  
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• December 31, 2025Atlas of Adult Congenital Heart Surgery

  Detailing various surgical procedures and considerations. The text covers fundamental surgical techniques like resternotomy and peripheral cannulation, including the use of specialized retractors and drills for chest entry. It also discusses surgical management of specific congenital heart conditions such as patent arterial duct, vascular rings, ventricular septal defects, and transposition of the great arteries, often including illustrations and detailed procedural steps. Furthermore, the sources address nomenclature changes from Latin to American English for clarity in cardiac terminology and explore complex topics like pacemaker lead management, endocarditis associated with congenital anomalies, and surgical approaches for valvular disease and arrhythmias in adult patients.
  
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• December 30, 2025Artificial Intelligence in Cancer Diagnosis and Prognosis: Breast and bladder cancer

  Focusing specifically on applications for breast and bladder cancer. The sources offer an in-depth review of computational techniques, primarily machine learning (ML) and deep learning (DL), used for tasks such as image classification, segmentation, and feature extraction for both cancer types. Several chapters discuss specific DL architectures, like Convolutional Neural Networks (CNNs), in modalities ranging from mammography and ultrasound to photoacoustic imaging and histopathological analysis. The volume also examines metabolomic analysis for bladder cancer, single-cell studies for breast cancer heterogeneity, and the challenges of data management and algorithm generalizability in clinical settings.
  
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• December 29, 2025Artificial Intelligence in Cancer Diagnosis and Prognosis: Brain and prostate cancer

  A comprehensive overview of artificial intelligence (AI) and machine learning (ML) applications in cancer diagnosis and treatment, particularly focusing on brain and prostate cancers. The text examines various methods, including deep convolutional neural networks (DCNNs) and the widely used U-Net architecture, for tasks like tumor segmentation, prognosis, and treatment planning within radiation oncology. Additionally, the sources discuss the challenges and solutions in handling medical image data—such as MRI, CT, and hyperspectral images—and address the need for data standardization and privacy protection through techniques like federated learning and explainable AI. Overall, the material highlights the rapidly advancing role of computational methods in improving the accuracy and efficiency of cancer care.
  
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• December 28, 2025Artificial Intelligence in Cancer Diagnosis and Prognosis: Lung and kidney cancer

  Focusing heavily on the application of machine learning (ML) and deep learning (DL) in the diagnosis, prognosis, and survival analysis of lung and renal (kidney) cell carcinoma. Several chapters detail novel algorithms, such as the CPL–BNNM algorithm for lung contour detection and the DeepMultiSurv model for multiview survival prediction, alongside discussions of common diagnostic imaging modalities like CT, MRI, and chest radiography. The sources also cover fundamental ML concepts, including the architecture of Convolutional Neural Networks (CNNs), the challenges of small medical datasets, and the importance of various quantitative evaluation metrics (e.g., Dice coefficient, accuracy, and AUC) used to assess model performance in these critical medical applications.
  
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• December 27, 2025Basic Radiation Oncology

  Covering essential concepts in cancer treatment. The content provides a comprehensive overview of the field, starting with fundamental radiation physics and radiobiology, including radiation-matter interaction and cell survival curves. The majority of the book details the clinical application of radiation therapy across various cancer types, such as those affecting the central nervous system, head and neck, genitourinary system, gastrointestinal system, and gynecological sites. It also discusses specific treatment modalities like intensity-modulated radiotherapy (IMRT), brachytherapy, and Total Body Irradiation (TBI), often referencing international standards and large clinical trials to guide treatment algorithms.
  
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