The “Whole Eye Transplant Moon Shot” refers to the ambitious research initiative at the Bascom Palmer Eye Institute to transplant a whole eye, including the optic nerve, with the goal of restoring vision in blind patients. This project is considered a “moonshot” due to the immense scientific and technical challenges involved in successfully transplanting and reconnecting all the intricate components of the eye, particularly the optic nerve.  The goal is to achieve whole eye transplantation, including the optic nerve, to restore vision in individuals with blindness. The project involves a team of experts in various fields, including ophthalmology, neurosurgery, and immunology.  The primary challenge is regenerating and reconnecting the optic nerve, which is part of the central nervous system and does not readily regenerate in adults.  The research is expected to lead to significant advancements in transplantation techniques, nerve regeneration, and potential cures for other diseases. 

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