In this episode we discuss one of our favorite pasttimes – exercise—and the relationship between exercise and health. Of course it’s no surprise that exercise is recommended for its health benefits, for people at any age and any level of fitness.  Dr. Gordon and I both prescribe exercise as one of the most important parts of our routine patient care.

 Today though we dive into what has surprised us both:  the hazards of ??too much?? exercise. 

 When might exercise have a dark side, when should we think twice about our exercise habits? And how might we tweak our exercise routine to get the most benefit from the time we do spend being active. Join us as we pore over some of the details.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

Treat ADHD, lower Alzheimer’s risk?

The episode explores emerging evidence that simply having ADD/ADHD raises lifetime Alzheimer’s risk—yet appropriately treating it in adults, often with low-dose stimulants, seems to push that risk back down. How can the same class of drugs be both feared as “brain-burning” and yet potentially brain-saving—and what does that mean for people already in midlife?

Treating prostate cancer successfully with--testosterone? 

Listeners are introduced to a first-in-oncology “directed evolution” case in metastatic prostate cancer, led by Dr. Lemanne’s team, where high-dose testosterone was deliberately used to expand treatment-sensitive cells—and only then was hormone blockade re-introduced. But did this radical, counterintuitive maneuver actually work?

Emotional trauma in youth as a hidden Alzheimer’s driver? Dr. Gordon discusses links between youth emotional trauma to higher rates of Alzheimer’s decades later, even in people who appear to have “moved on.” Is this just correlation, or should early emotional trauma be considered a subtle form of brain injury that can and should be addressed?

Do you go to bed later on weekends, by just 1-2 hours, but make up for it by rising later?  If so, you'll want to know that you may be increasing your risk of breast or prostate cancer.  This episode explores that research.

Have you heard of the new Alzheimer’s blood tests, that improve as the patient improves, allowing better direction of treatment? 

Dr. Gordon walks us through the ATN panel (amyloid-beta, p-tau, neurofilament light), now accessible through routine laboratory tests, along with galectin-3 as a tau-clustering, inflammation-linked marker, and a new infusion drug (TB006) targeting that pathway. But can these numbers really be moved in the right direction with targeted lifestyle and medical interventions—and what happens when they are?

Enjoy this unusual episode! 

And write to us. We read every email.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

In today's episode, we have the pleasure of a chat with my longtime friend and colleague, Dr. Ann Hathaway. Dr. Hathaway enlightens us on some of the details of her work with Dr. Dale Bredesen, delving into some aspects of the treatment for mold toxicity and hormone replacement therapy for older women. Dr. Lemanne also has a chance to share some insightful details about her innovative work with hormone pulsing as potential treatment for some hormone sensitive cancers. Join us as we explore these exciting topics and more. It's my pleasure today to welcome to our podcast, our guest, Dr. Ann Hathaway 

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

In this episode, we uncover the strange fact that 11-year solar cycles shape your health, including your risk of cancer and autoimmune diseases. 

I'll admit this sounds like astrology. Or science fiction. 

It isn't.

Statistics show that the number of sunspots during the year you were born  shortens your lifespan, on average, by more than a decade. 

And sunlight affects us in other strange ways. You may also be surprised to learn that living on the far western side of your time zone, or simply eating supper 8 PM compared to 6 PM, is associated with an increased risk of cancer.

This episode also covers

• why your cancer risk rises as you live farther from the equator (it's not all vitamin D)
• how changing your bedtime each night--by less than an hour!--quietly raises your risk of early death
• why your hospital room window determines how fast you heal

You’ll hear surprising data, real patient stories, and practical takeaways you can implement tonight. 

Want even more? Find out how muscle size correlates with brain size. (Yep.)

And if you want your exercise to actually build muscle, Dr. Gordon tells you the best time of day to get moving.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

What doesn't kill me makes me...weaker?

Learn why short bursts of stress are a tonic, while chronic stress damages your brain and accelerates tumor growth. Especially if you're female.  

Find out why you're wrong about your own stress levels, and what you must do to find the hidden stress before you can fix it.

Discover which meditation practices actually calm your nervous system. Many of the most popular simply won't work for you. The doctors themselves get completely opposite results from the same techniques. 

Dump the widespread belief that any exercise is fights cancer. For example, the walking routines doctors recommend do almost nothing. Find out what the data show actually works to stunt cancer growth.

Plus, learn about the overlooked hormone (most PCPs never think about this) your stressed body steals from your brain, how this theft leaves your brain vulnerable to stress-induced damage, and how Dr Gordon fixes this in her patients with an over-the-counter supplement.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

Surgery can wake up dormant cancer cells—even if the surgery is unrelated to cancer. In this striking episode, Drs. Dawn Lemanne and Deborah Gordon uncover how surgical trauma and anesthesia suppress immune function for weeks, creating an ideal window for tumor growth. Listen in as they discuss powerful, little-known tools to counteract this: a flu shot given within 24 hours before surgery can preserve immune surveillance; which painkillers to avoid after surgery; and how Cialis may reduce metastatic risk when used preoperatively. Bonus: Learn how heart rate variability reveals immune strength and insulin sensitivity. 

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

Yes we all want to live longer, but the catch of course is -- so long as we are healthy!  What are some of the current thoughts about living longer and living better. How can we extend our vitality as we age, so that we celebrate health and not just more birthdays.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

Your Bones Are Lying to You – What the Experts Aren’t Telling You

In this myth-busting episode, medical exercise specialist Andy Baxter flips everything you thought you knew about bone health upside down.

Why Your Daily Walk--a False Security Blanket?
Think walking strenghthens your muscles and protects your bones? Think again. Discover why it fails to give you what you really need to prevent life-altering falls—and what to do instead.

Swimmers and Cyclists, Brace Yourselves…
Low-impact exercise sounds great—until you hear why some athletes have weaker bones than couch potatoes.

The CDC’s Bizarre Osteoporosis ‘Cure’
Would you believe field hockey for strenghthening bones was once an official recommendation? Find out what that says about mainstream osteoporosis advice—and why it’s time to rethink it.

80-Year-Old Diane’s Secret to Jumping Higher Than You
An explosive workout transformed this grandmother’s strength—but there’s a catch: your brain will actively try to stop you from doing the same. How to tame your brain so it is on the same team as your bones and joints.

Your Brain Is Sabotaging Your Joints
Meet neuromediation, the hidden reason arthritis pain worsens—and the surprising exercises that rewire your brain to fight back.

Why Bone Density Scans Miss 80% of Fracture Risks
Your DEXA scan isn’t telling you the whole story. So what actually predicts a broken hip? The answer will change how you think about osteoporosis.

Creatine + Coffee = Flushing $$$ Down the Drain?
A world-renowned researcher shares a timing hack that makes supplements actually work. Here is a link to a dosing guideline mentioned in the episode. (You must be sure to check with your own doctor before starting any supplement!)

Swimmers and Cyclists, Brace Yourselves…
Low-impact exercise sounds great—until you hear why some athletes have weaker bones than couch potatoes.

This isn’t about aging gracefully—it’s about aging powerfully. Ready to rewrite the rules? Listen now.

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

In this episode, we sit down with Dr.  Nick Norwitz, who is, in his own words, a researcher educator whose mission is to make metabolic health mainstream. Dr. Norwitz has a PhD in human metabolism from Oxford University and is about to get an MD from Harvard Medical School. We are interested here in his own story of healing chronic illness, in which modern standard medicine absolutely failed him and forced him to find his own path back to health. And this sheds a lot of light on the value of individualizing metabolic health care. And in fact, his story illustrates the n of 1 model of health care, which can often be the only way to work out the best diet or best therapy for whatever ails us and which I believe is the future of medicine.

Doctor Norwitz also shares his insights about the process of human change and just exactly what motivated him when he knew he needed to make changes for his own survival. Join us as we chat with the very doctor Norwitz, and be sure to check out the show notes for links to all of his social media appearances. These are not only brilliant but highly entertaining.

Here are links to just a few of his many ventures:
https://www.youtube.com/@nicknorwitzPhD

on X: https://x.com/nicknorwitz

Instagram: https://www.instagram.com/nicknorwitz/ 

and for links to all his publications and writings, visit his website @ 

https://www.nicknorwitz.com/

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains

In this episode of Docs Talk Shop, Dr. Lemanne and Dr. Gordon explore how daily rhythms impact cancer treatment, brain health, and metabolism. Discover surprising ways to optimize your health by carefully timing your sleep, light exposure, and meals. (And think twice about late suppers!)

• Breast cancers spread at night, and why this means trouble if your largest meal is supper.
• In colorectal cancer patients, morning chemo benefits men, while afternoon chemo benefits women.
• Light exposure at night disrupts sleep in everyone, immediately increasing the risk of diabetes and cancer.
• Vigorous exercise instantly creates cancer-killing effects in the blood that last for two hours.
• A single night of poor sleep causes high blood glucose and junk food cravings the very next day.

References:

Metastatic spread of breast cancer accelerates during sleep. Nature 2022
https://pubmed.ncbi.nlm.nih.gov/35732738/

Reducing nighttime light exposure in the urban environment to benefit human health and society. Science. https://www.science.org/doi/epdf/10.1126/science.adg5277. Accessed September 25, 2024.

Effects of anthropogenic light on health. Science. https://www.science.org/doi/10.1126/science.adg3173. Accessed September 25, 2024.

Light disrupts sleep and metabolic health. NPR. https://www.npr.org/sections/health-shots/2022/04/01/1089997121/light-disrupts-sleep. Accessed September 25, 2024.

Disruption of sleep due to light exposure increases insulin resistance and heart rate. PNAS. https://www.pnas.org/doi/10.1073/pnas.2113290119. Accessed September 25, 2024.

West KE, Jablonski MR, Warfield B, et al. Blue light exposure suppresses melatonin and impacts circadian rhythms. J Biol Rhythms. 2015;30(6):537-546. https://pubmed.ncbi.nlm.nih.gov/30311830/. Accessed September 25, 2024.

Effects of artificial light at night on human health: a review of epidemiological studies. Int J Occup Med Environ Health. 2015;28(4):563-571. https://pubmed.ncbi.nlm.nih.gov/26375320/. Accessed September 25, 2024.

Chronic sleep restriction minimizes circadian disruption, preserving glucose tolerance. Diabetes Care. 2021;44(3):839-844. https://pubmed.ncbi.nlm.nih.gov/34744800/. Accessed September 25, 2024.

Circadian rhythms and cognitive function. Nat Rev Neurosci. 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743892/. Accessed September 25, 2024.

Hall J, Rosbash M, Young M. Nobel Prize in Physiology or Medicine 2017: research on circadian rhythms. Nobel Prize Press Release. https://www.nobelprize.org/prizes/medicine/2017/press-release/. Accessed September 25, 2024.

Light at night and increased stroke risk. Stroke. 2024. https://www.sciencedaily.com/releases/2024/03/240325172425.htm. Accessed September 25, 2024.

Association of light exposur

Dawn Lemanne, MD
Oregon Integrative Oncology
Leave no stone unturned.

Deborah Gordon, MD
Northwest Wellness and Memory Center
Building Healthy Brains