Dr. Howard Smith Reports

Vidcast:  https://youtu.be/tTmjDS-xJr4

Vaccination with the Moderna CoVid vaccine triggers more IgA anti-CoVid antibodies and anti-CoVid killer T cells compared with the Pfizer vaccine.  Researchers at Harvard and MIT studied the immune responses of 73 vaccine recipients including 28 who received the Moderna vaccine and 45 who received the Pfizer vaccine.

Analysis of the immune responses to each vaccine indicate that the Moderna vaccine produces more IgA secretory antibodies to CoVid spike, receptor binding domain, and N-terminal domain antigens.  On the cell-mediated immunity front, Moderna vaccine triggers enhanced antibody dependent neutrophil phagocytosis and antibody dependent killer cell activation.  Both vaccines produce similar IgG and IgM anti-CoVid antibody levels. 

In terms of immunity against the variants, Moderna triggers more antibodies in secretions, IgA antibodies, while Pfizer trigger more blood-borne antibodies, IgG and IgM.  However, the additional IgA, RBD,  and NTD antibodies triggered by Moderna in comparison to Pfizer may explain its better performance against variants including Delta.

https://www.biorxiv.org/content/10.1101/2021.08.31.458247v1.full.pdf

#CoVid #vaccine #Moderna #Pfizer #antibodies #cellularimmunity

Vidcast:  https://youtu.be/tTmjDS-xJr4

Vaccination with the Moderna CoVid vaccine triggers more IgA anti-CoVid antibodies and anti-CoVid killer T cells compared with the Pfizer vaccine.  Researchers at Harvard and MIT studied the immune responses of 73 vaccine recipients including 28 who received the Moderna vaccine and 45 who received the Pfizer vaccine.

Analysis of the immune responses to each vaccine indicate that the Moderna vaccine produces more IgA secretory antibodies to CoVid spike, receptor binding domain, and N-terminal domain antigens.  On the cell-mediated immunity front, Moderna vaccine triggers enhanced antibody dependent neutrophil phagocytosis and antibody dependent killer cell activation.  Both vaccines produce similar IgG and IgM anti-CoVid antibody levels. 

In terms of immunity against the variants, Moderna triggers more antibodies in secretions, IgA antibodies, while Pfizer trigger more blood-borne antibodies, IgG and IgM.  However, the additional IgA, RBD,  and NTD antibodies triggered by Moderna in comparison to Pfizer may explain its better performance against variants including Delta.

https://www.biorxiv.org/content/10.1101/2021.08.31.458247v1.full.pdf

#CoVid #vaccine #Moderna #Pfizer #antibodies #cellularimmunity

Vidcast:  https://youtu.be/8YtIcbsg2ls

Seventy-two percent of adults and parents of children with food allergies are unaware that oral immunotherapy is an effective, painless, and convenient alternative to allergy shots.  This the conclusion of a nationwide survey of some 781 respondents conducted by pediatric researchers at Northwestern University and Chicago’s Lurie Children’s Hospital.

When the survey numbers were crunched, the data showed that more than 95% of food allergy sufferers had never been offered oral immunotherapy.  We’re not talking about small number of people either since 10% of American adults or 33,100,000 adults and 8% of children or 5,040,000 kids have food allergies.

So if you have food allergies or, for that matter, any allergies, ask your allergist about oral immunotherapy.  It can be DIY at home without needles or visits.

https://www.sciencedirect.com/science/article/abs/pii/S2213219821008229?via%3Dihub

#allergy #oralimmunotherapy #oit #foodallergy

Vidcast:  https://youtu.be/8YtIcbsg2ls

Seventy-two percent of adults and parents of children with food allergies are unaware that oral immunotherapy is an effective, painless, and convenient alternative to allergy shots.  This the conclusion of a nationwide survey of some 781 respondents conducted by pediatric researchers at Northwestern University and Chicago’s Lurie Children’s Hospital.

When the survey numbers were crunched, the data showed that more than 95% of food allergy sufferers had never been offered oral immunotherapy.  We’re not talking about small number of people either since 10% of American adults or 33,100,000 adults and 8% of children or 5,040,000 kids have food allergies.

So if you have food allergies or, for that matter, any allergies, ask your allergist about oral immunotherapy.  It can be DIY at home without needles or visits.

https://www.sciencedirect.com/science/article/abs/pii/S2213219821008229?via%3Dihub

#allergy #oralimmunotherapy #oit #foodallergy

Vidcast:  https://youtu.be/vBtj9iV8pSA

At the end of August, the World Health Organization announced another variant of interest, classified at B.1.621 and commonly known as the Mu variant.  This variant encompasses a constellation of mutations that could render it more impervious to the anti-CoVid antibodies generated by our current vaccine.   Early data suggests that its vaccine resistance is likely similar to the South African B.1.35l variant, and our mRNA vaccines should offer good protection, particularly against severe and life-threatening disease. 

It first arose in Colombia where its current prevalence is 39%.  Mu has spread to over 40 countries including the US.  Its global prevalence to date is low.  Over 2,000 Mu cases have been identified in the US.  It is most prevalent in Alaska representing almost 4% of cases there.  In the continental US, it is most prevalent in California followed by Florida, New York, New Jersey, Washington state, and Texas.

We don’t have solid data as yet to estimate its transmissibility rate and ability to create severe or fatal disease.  Stay tuned.

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20210831_weekly_epi_update_55.pdf?sfvrsn=e33e80ba_7&download=true

https://medicalxpress.com/news/2021-09-coronavirus-variant-mu-1.html

https://www.webmd.com/lung/news/20210902/who-tracking-new-covid-variant-called-mu

https://www.newsweek.com/cases-mu-covid-variant-that-may-evade-vaccines-found-these-states-1625144

#CoVid #mu #variant #who

Vidcast:  https://youtu.be/vBtj9iV8pSA

At the end of August, the World Health Organization announced another variant of interest, classified at B.1.621 and commonly known as the Mu variant.  This variant encompasses a constellation of mutations that could render it more impervious to the anti-CoVid antibodies generated by our current vaccine.   Early data suggests that its vaccine resistance is likely similar to the South African B.1.35l variant, and our mRNA vaccines should offer good protection, particularly against severe and life-threatening disease. 

It first arose in Colombia where its current prevalence is 39%.  Mu has spread to over 40 countries including the US.  Its global prevalence to date is low.  Over 2,000 Mu cases have been identified in the US.  It is most prevalent in Alaska representing almost 4% of cases there.  In the continental US, it is most prevalent in California followed by Florida, New York, New Jersey, Washington state, and Texas.

We don’t have solid data as yet to estimate its transmissibility rate and ability to create severe or fatal disease.  Stay tuned.

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20210831_weekly_epi_update_55.pdf?sfvrsn=e33e80ba_7&download=true

https://medicalxpress.com/news/2021-09-coronavirus-variant-mu-1.html

https://www.webmd.com/lung/news/20210902/who-tracking-new-covid-variant-called-mu

https://www.newsweek.com/cases-mu-covid-variant-that-may-evade-vaccines-found-these-states-1625144

#CoVid #mu #variant #who

Vidcast:  https://youtu.be/4r8Mzi1m-U0

The FDA and Rocky Top Farms have recalled Rocky Top Farms Cherry Butter.  This product, sold in clear 10 ounce jars, contains undeclared milk.  Those with milk allergies could develop a serious or life-threatening allergic reaction after ingesting this cherry butter.  This product was sold nationwide via the website rockymountainfarms.com.  If you purchased this cherry butter, return it to the place of purchase for a refund.  If you have questions, reach Rocky Top Farms by phone at 1-231-350-0985.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/rocky-top-farms-issues-allergy-alert-undeclared-milk-cherry-butter

#rocktyopfarms #cherrybutter #milk #allergy #recall

Vidcast:  https://youtu.be/4r8Mzi1m-U0

The FDA and Rocky Top Farms have recalled Rocky Top Farms Cherry Butter.  This product, sold in clear 10 ounce jars, contains undeclared milk.  Those with milk allergies could develop a serious or life-threatening allergic reaction after ingesting this cherry butter.  This product was sold nationwide via the website rockymountainfarms.com.  If you purchased this cherry butter, return it to the place of purchase for a refund.  If you have questions, reach Rocky Top Farms by phone at 1-231-350-0985.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/rocky-top-farms-issues-allergy-alert-undeclared-milk-cherry-butter

#rocktyopfarms #cherrybutter #milk #allergy #recall

Vidcast:  https://youtu.be/46QSqXL9_YQ

The FDA and KBF Inc. have recalled Banoful Top Orange Biscuits.  This food contains undeclared milk, and those with milk allergies could develop serious or life-threatening allergic reactions should they eat these biscuits.  This bakery item was sold nationwide through retail stores and mail order outlets.  If you purchased these biscuits, return them to the place of purchase for a refund.  For additional information, call KBF at 1-646-714-4062.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/kbf-inc-issues-allergy-alert-undeclared-milk-allergens-banoful-top-orange-biscuit

#kbf #biscuits #milk #allergy #recall

Vidcast:  https://youtu.be/46QSqXL9_YQ

The FDA and KBF Inc. have recalled Banoful Top Orange Biscuits.  This food contains undeclared milk, and those with milk allergies could develop serious or life-threatening allergic reactions should they eat these biscuits.  This bakery item was sold nationwide through retail stores and mail order outlets.  If you purchased these biscuits, return them to the place of purchase for a refund.  For additional information, call KBF at 1-646-714-4062.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/kbf-inc-issues-allergy-alert-undeclared-milk-allergens-banoful-top-orange-biscuit

#kbf #biscuits #milk #allergy #recall