Dr. Howard Smith Reports

Vidcast:  https://youtu.be/LsH7UZN_Fz4

Today’s medical discoveries that point to future therapy:

Ultrasonic Patch Warns Of Strokes and Heart Attacks

Electromagnetic Helmet Helps Shrink Brain Tumor

Copper Tranporter Gene Triggers Blood Vessel Repair

New Cancer Immunotherapy Emerging

Nanodressing Turbocharges Wound Healing

UC-San Diego have developed a soft, flexible ultrasound generating patch that, when worn on the skin of the neck or chest, can report blood flow problems major arteries feeding the brain and heart.  The phased array of ultrasound transducers in the patch work continuously to measure blood flow in vessels as deep as 6 inches within the body.  The ultrasound beam may also be electronically tilted for measurements of vessels not directly beneath the patch.

An oscillating magnetic field generated within a wearable helmet has driven shrinkage of an otherwise untreatable brain tumor by 30%.  Neurosurgical investigators at the Houston Methodist Research Institute report the case of a 53 year old man with an end-stage, recurrent frontal lobe glioblastoma given this electromagnetic therapy for 5 weeks.  Looks for more work in this arena.

Medical College of Georgia cardiologists report that the gene responsible for copper transport and utilization also promotes the healing of ailing blood vessels.  In a biochemical cascade, the product of this gene, ATP7A, triggers activity of the blood vessel growth factor VEGFR2.  Acquiring control over this process could help halt vascular deterioration in diabetics and others with chronic vascular disease.

There are new cancer immunotherapy agents in town called anti-TIGIT antibodies, and they prevent TIGIT from dialing down killer T cell activity against cancer cells.  The major drug companies are all battling to get their hands on these experimental agents.  GlaxoSmithKline just bought rights to EOS-448, BristolMyersSquibb bought AGEN1777, Gilead  AB154, and Roche has already tested its tiragolumab in combination with another checkpoint inhibitor in phase 2 trials.  Stay tuned on this one.

A wound nanodressing composed of thin threads of natural materials including collagen as well as wound healing promotion agents may provide a cost effective means of helping diabetics and others with chronic vascular disease.  Michigan State bioengineers helmed a multinational group that has developed these dressings aiming to keep the eventual cost as low as $20 per unit by employing readily available biopolymers.

These and other cutting edge solutions are coming to your doctor’s office and our hospitals…….some day soon!

https://www.nature.com/articles/s41551-021-00763-4

https://www.frontiersin.org/articles/10.3389/fonc.2021.708017/full

https://www.nature.com/articles/s41467-021-23408-1

https://cen.acs.org/pharmaceuticals/biologics/GSK-buy-iTeosanti-TIGIT-antibody/99/i23

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Vidcast:  https://youtu.be/LsH7UZN_Fz4

Today’s medical discoveries that point to future therapy:

Ultrasonic Patch Warns Of Strokes and Heart Attacks

Electromagnetic Helmet Helps Shrink Brain Tumor

Copper Tranporter Gene Triggers Blood Vessel Repair

New Cancer Immunotherapy Emerging

Nanodressing Turbocharges Wound Healing

UC-San Diego have developed a soft, flexible ultrasound generating patch that, when worn on the skin of the neck or chest, can report blood flow problems major arteries feeding the brain and heart.  The phased array of ultrasound transducers in the patch work continuously to measure blood flow in vessels as deep as 6 inches within the body.  The ultrasound beam may also be electronically tilted for measurements of vessels not directly beneath the patch.

An oscillating magnetic field generated within a wearable helmet has driven shrinkage of an otherwise untreatable brain tumor by 30%.  Neurosurgical investigators at the Houston Methodist Research Institute report the case of a 53 year old man with an end-stage, recurrent frontal lobe glioblastoma given this electromagnetic therapy for 5 weeks.  Looks for more work in this arena.

Medical College of Georgia cardiologists report that the gene responsible for copper transport and utilization also promotes the healing of ailing blood vessels.  In a biochemical cascade, the product of this gene, ATP7A, triggers activity of the blood vessel growth factor VEGFR2.  Acquiring control over this process could help halt vascular deterioration in diabetics and others with chronic vascular disease.

There are new cancer immunotherapy agents in town called anti-TIGIT antibodies, and they prevent TIGIT from dialing down killer T cell activity against cancer cells.  The major drug companies are all battling to get their hands on these experimental agents.  GlaxoSmithKline just bought rights to EOS-448, BristolMyersSquibb bought AGEN1777, Gilead  AB154, and Roche has already tested its tiragolumab in combination with another checkpoint inhibitor in phase 2 trials.  Stay tuned on this one.

A wound nanodressing composed of thin threads of natural materials including collagen as well as wound healing promotion agents may provide a cost effective means of helping diabetics and others with chronic vascular disease.  Michigan State bioengineers helmed a multinational group that has developed these dressings aiming to keep the eventual cost as low as $20 per unit by employing readily available biopolymers.

These and other cutting edge solutions are coming to your doctor’s office and our hospitals…….some day soon!

https://www.nature.com/articles/s41551-021-00763-4

https://www.frontiersin.org/articles/10.3389/fonc.2021.708017/full

https://www.nature.com/articles/s41467-021-23408-1

https://cen.acs.org/pharmaceuticals/biologics/GSK-buy-iTeosanti-TIGIT-antibody/99/i23

https://pubmed.ncbi.nlm.nih.gov/31828774/

https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.1c00400

#ultrasoundpatch #oncomagnetictherapy #glioblastoma #TIGIT #antitigit #checkpointinhbitor #wounds #diabetes

Vidcast:  https://youtu.be/aOiW0QoED40

The FDA and 5000 Years Foods now now recall 5000 Years Kimchi Products.  These products are contaminated with listeria monocytogenes, a bacterium that causes severe and sometimes fatal infections in the young, old, and immunosuppressed.  It can cause miscarriages and stillbirths.  This product was distributed in IL but sold nationwide.  If you have any of this kimchi, don’t consume it.  Return it to the point of purchase for a refund.  For additional information, call 5000 Years Foods by phone at 1-773-509-8600.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/5000-years-foods-inc-recall-cabbage-kimchi-because-possible-health-risk

#5000yearsfoods #kimchi #listeria #sepsis #recall

Vidcast:  https://youtu.be/aOiW0QoED40

The FDA and 5000 Years Foods now now recall 5000 Years Kimchi Products.  These products are contaminated with listeria monocytogenes, a bacterium that causes severe and sometimes fatal infections in the young, old, and immunosuppressed.  It can cause miscarriages and stillbirths.  This product was distributed in IL but sold nationwide.  If you have any of this kimchi, don’t consume it.  Return it to the point of purchase for a refund.  For additional information, call 5000 Years Foods by phone at 1-773-509-8600.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/5000-years-foods-inc-recall-cabbage-kimchi-because-possible-health-risk

#5000yearsfoods #kimchi #listeria #sepsis #recall

Xcvid https://youtu.be/J8gszIFtAAQ

The FDA and Johnson and Johnson are recalling Neutrogena and Aveeno Aerosol Sunscreen Products.  These products contain unsafe levels of the organic solvent benzene.   This agent is a human carcinogen.  If you have any of these products, stop using them and call Johnson and Johnson’s Consumer Care Center by phone at 1-800-458-1673 to check if the product you have is affected and to arrange a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/johnson-johnson-consumer-inc-issues-voluntary-recall-specific-neutrogenar-and-aveenor-aerosol

#sunscreen #aveeno #neutrogena #aerosol #benzene #recall

Xcvid https://youtu.be/J8gszIFtAAQ

The FDA and Johnson and Johnson are recalling Neutrogena and Aveeno Aerosol Sunscreen Products.  These products contain unsafe levels of the organic solvent benzene.   This agent is a human carcinogen.  If you have any of these products, stop using them and call Johnson and Johnson’s Consumer Care Center by phone at 1-800-458-1673 to check if the product you have is affected and to arrange a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/johnson-johnson-consumer-inc-issues-voluntary-recall-specific-neutrogenar-and-aveenor-aerosol

#sunscreen #aveeno #neutrogena #aerosol #benzene #recall

Vidcast:  https://youtu.be/U_0EPJok3X4

The FDA and Bright Farms now recall Bright Farms Salad Greens.  These lettuce varieties are contaminated with salmonella.  Salmonella cause a serious and sometimes fatal gastroenteritis and sepsis in the young, elders, and those with complicating medical issues.  This lettuce has been sold in IL, WI, IA, and IN at various stores including Mariano’s, Walmart, Strack Van Till, Sullivans, Caputo’s, Jewel-Osco, Pick ’N Save, Metro Market, Copps, and Tadych’s.  If you purchased greens at any of these outlets, don’t consume it but call Bright Farms by phone at 1-866-857-8745 to check if the product you have has been recalled.  If in doubt, return it to the point of purchase for a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/brightfarms-announces-voluntary-recall-packaged-salad-greens-sold-illinois-wisconsin-iowa-and

#brightfarms #lettuce #salmonella #gastroenteritis #recall

Vidcast:  https://youtu.be/U_0EPJok3X4

The FDA and Bright Farms now recall Bright Farms Salad Greens.  These lettuce varieties are contaminated with salmonella.  Salmonella cause a serious and sometimes fatal gastroenteritis and sepsis in the young, elders, and those with complicating medical issues.  This lettuce has been sold in IL, WI, IA, and IN at various stores including Mariano’s, Walmart, Strack Van Till, Sullivans, Caputo’s, Jewel-Osco, Pick ’N Save, Metro Market, Copps, and Tadych’s.  If you purchased greens at any of these outlets, don’t consume it but call Bright Farms by phone at 1-866-857-8745 to check if the product you have has been recalled.  If in doubt, return it to the point of purchase for a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/brightfarms-announces-voluntary-recall-packaged-salad-greens-sold-illinois-wisconsin-iowa-and

#brightfarms #lettuce #salmonella #gastroenteritis #recall

Vidcast:  https://youtu.be/JPbLKTP9mD8

The FDA and Alpha Male Plus now recall Alpha Male Plus Male Enhancer Fruit Chew.  This dietary supplement is laced with tadalafil, a prescription medication for erectile dysfunction branded as cialis, that makes this over-the-counter product an unapproved drug with unproven safety and effectiveness.  The contaminating phosphodiesterase is a risk for those taking nitrates such as nitroglycerin as it potentiates this drug’s blood pressure lowering to unsafe levels.  This drug has been compounded by a Dr. Manuel Mascarenas in Arizona who operates Alpha Male Plus.  If you have this supplement, stop using it and contact the company at 1-520-955-2015 to arrange for a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/alpha-male-plus-issues-voluntary-nationwide-recall-alpha-male-plus-male-enhancer-due-presence

#alphamaleplus #tadalafil #cialis #phosphodiesterase #hypotension #recall

Vidcast:  https://youtu.be/JPbLKTP9mD8

The FDA and Alpha Male Plus now recall Alpha Male Plus Male Enhancer Fruit Chew.  This dietary supplement is laced with tadalafil, a prescription medication for erectile dysfunction branded as cialis, that makes this over-the-counter product an unapproved drug with unproven safety and effectiveness.  The contaminating phosphodiesterase is a risk for those taking nitrates such as nitroglycerin as it potentiates this drug’s blood pressure lowering to unsafe levels.  This drug has been compounded by a Dr. Manuel Mascarenas in Arizona who operates Alpha Male Plus.  If you have this supplement, stop using it and contact the company at 1-520-955-2015 to arrange for a refund.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/alpha-male-plus-issues-voluntary-nationwide-recall-alpha-male-plus-male-enhancer-due-presence

#alphamaleplus #tadalafil #cialis #phosphodiesterase #hypotension #recall