Dr. Howard Smith Reports

Vidcast:  https://youtu.be/NfYWwzdOiuM

The B.1.526 variant, first appearing in New York in December, has seen more than a 26 fold increase over a one month period.  This variant contains the E484K, S477N, and the D253G mutations.

These mutations reduce therapeutic value of convalescent immune sera from recovered patients as well as commercial monoclonal antibodies.  They may also lower vaccine effectiveness.

The mutations permit the B.1.526 variant to bind more tightly to respiratory linings. Non-vaccinated individuals may get sicker and the vaccinated may become CoVid carriers who spread virus to vulnerable persons.

These variants make continued mask wearing and distancing a must.  Use of Covid-killing nasal sprays like Xlear could be helpful.

https://www.medrxiv.org/content/10.1101/2021.02.26.21251868v1.full.pdf+html

#CoVid #variants #newyork #b1526 #xlear #nasalspray

Vidcast:  https://youtu.be/NfYWwzdOiuM

The B.1.526 variant, first appearing in New York in December, has seen more than a 26 fold increase over a one month period.  This variant contains the E484K, S477N, and the D253G mutations.

These mutations reduce therapeutic value of convalescent immune sera from recovered patients as well as commercial monoclonal antibodies.  They may also lower vaccine effectiveness.

The mutations permit the B.1.526 variant to bind more tightly to respiratory linings. Non-vaccinated individuals may get sicker and the vaccinated may become CoVid carriers who spread virus to vulnerable persons.

These variants make continued mask wearing and distancing a must.  Use of Covid-killing nasal sprays like Xlear could be helpful.

https://www.medrxiv.org/content/10.1101/2021.02.26.21251868v1.full.pdf+html

#CoVid #variants #newyork #b1526 #xlear #nasalspray

Vidcast:  https://youtu.be/huVl5qZPaOI

Two doses of the Novavax full length CoVid spike protein-nano particle vaccine induced significantly high and effective titers of IgG anti-CoVid antibody.  Novavax Inc. has just published these results on the pre-publication online server medrixiv.org.

A total of 1256 participants at 17 sites in the US and Australia completed the blinded, randomized study that tested 2 concentrations of the vaccine in 1 and 2 dose regimens.  The 2 doses employing 5 ug of vaccine triggered the highest levels of antibody with the lowest numbers of side effects.

This vaccine now moves on to Phase 3 testing before it can be presented to the FDA for an emergency use authorization.

https://www.medrxiv.org/content/10.1101/2021.02.26.21252482v1.full.pdf+html

#CoVid #novavax #vaccine #nanoparticle

Vidcast:  https://youtu.be/huVl5qZPaOI

Two doses of the Novavax full length CoVid spike protein-nano particle vaccine induced significantly high and effective titers of IgG anti-CoVid antibody.  Novavax Inc. has just published these results on the pre-publication online server medrixiv.org.

A total of 1256 participants at 17 sites in the US and Australia completed the blinded, randomized study that tested 2 concentrations of the vaccine in 1 and 2 dose regimens.  The 2 doses employing 5 ug of vaccine triggered the highest levels of antibody with the lowest numbers of side effects.

This vaccine now moves on to Phase 3 testing before it can be presented to the FDA for an emergency use authorization.

https://www.medrxiv.org/content/10.1101/2021.02.26.21252482v1.full.pdf+html

#CoVid #novavax #vaccine #nanoparticle

Vidcast:  https://youtu.be/0_urGjMLqwU

Those engaging in physical activities more than once a week are 52% less likely to require hospitalization should they become infected with CoVid compared with couch potatoes.  French, Canadian, and Swiss investigators analyzed data from 3,139 European participants.

As expected, even with exercise, the odds of hospitalization for CoVid were more than double for those 65-75 years of age compared with 50 to 64 year olds.  The odds quadrupled for those 75 to 96 years of age.  Those with the greatest muscle strength fared the best.

Other studies show that moderate physical activity does stimulate the immune system.  When you exert without overdoing, the immune stimulus is protective.

https://www.medrxiv.org/content/10.1101/2021.02.25.21252451v1.full.pdf+html

#CoVid #hospitalization #exercise #musclestrength

Vidcast:  https://youtu.be/0_urGjMLqwU

Those engaging in physical activities more than once a week are 52% less likely to require hospitalization should they become infected with CoVid compared with couch potatoes.  French, Canadian, and Swiss investigators analyzed data from 3,139 European participants.

As expected, even with exercise, the odds of hospitalization for CoVid were more than double for those 65-75 years of age compared with 50 to 64 year olds.  The odds quadrupled for those 75 to 96 years of age.  Those with the greatest muscle strength fared the best.

Other studies show that moderate physical activity does stimulate the immune system.  When you exert without overdoing, the immune stimulus is protective.

https://www.medrxiv.org/content/10.1101/2021.02.25.21252451v1.full.pdf+html

#CoVid #hospitalization #exercise #musclestrength

Vidcast:  https://youtu.be/naMxqevNDBs

The first dose of the Pfizer vaccine appears to be 93-94% effective at preventing CoVid, a significantly higher number than the originally reported 52%.  This new information comes from two independent research groups, one in Canada and the other in Australia, after they revisited the data from Pfizer’s phase 3 studies of this vaccine’s potency.

The Canadian group looked at data compiled at 21 days just before the second dose, while the Australian group used a sophisticated mathematical model to show the first dose reaches full efficiency by day 11.  Their analysis of Moderna data showed a similar result.

But don’t skip the second dose just yet as it may ensure protection longevity.

https://www.nejm.org/doi/full/10.1056/NEJMc2036242

https://www.medrxiv.org/content/10.1101/2021.02.23.21252315v1.full.pdf+html

#CoVid #vaccine #mRNA #pfizer #moderna

Vidcast:  https://youtu.be/naMxqevNDBs

The first dose of the Pfizer vaccine appears to be 93-94% effective at preventing CoVid, a significantly higher number than the originally reported 52%.  This new information comes from two independent research groups, one in Canada and the other in Australia, after they revisited the data from Pfizer’s phase 3 studies of this vaccine’s potency.

The Canadian group looked at data compiled at 21 days just before the second dose, while the Australian group used a sophisticated mathematical model to show the first dose reaches full efficiency by day 11.  Their analysis of Moderna data showed a similar result.

But don’t skip the second dose just yet as it may ensure protection longevity.

https://www.nejm.org/doi/full/10.1056/NEJMc2036242

https://www.medrxiv.org/content/10.1101/2021.02.23.21252315v1.full.pdf+html

#CoVid #vaccine #mRNA #pfizer #moderna

Vidcast:  https://youtu.be/7zYYi0fZx0Q

The FDA and El Abuelito Cheese now recall all Quesco Fresco products with sell dates through 3/28/21 due to the possibility that they are contaminated with listeria monocytogenes.  This micro-organism may cause serious and sometimes fatal infections in the very young, elders, or in the immunocompromised.  It may cause miscarriages and stillbirths.  El Abuelito products were sold in CT, NJ, PA, NY; Rio Grande Food Products sold  in VA, NC, MD; and Rio Lindo products sold in in NC and MD. If you bought any of these products, don’t consume them but return them to the place of purchase for a refund.  Call El Abuelito at 1-973-345-3503 with questions.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/el-abuelito-recalls-queso-fresco-products-because-possible-health-risk

#queso #elabuelito #riogrande #riolindo #listeria #recall

Vidcast:  https://youtu.be/7zYYi0fZx0Q

The FDA and El Abuelito Cheese now recall all Quesco Fresco products with sell dates through 3/28/21 due to the possibility that they are contaminated with listeria monocytogenes.  This micro-organism may cause serious and sometimes fatal infections in the very young, elders, or in the immunocompromised.  It may cause miscarriages and stillbirths.  El Abuelito products were sold in CT, NJ, PA, NY; Rio Grande Food Products sold  in VA, NC, MD; and Rio Lindo products sold in in NC and MD. If you bought any of these products, don’t consume them but return them to the place of purchase for a refund.  Call El Abuelito at 1-973-345-3503 with questions.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/el-abuelito-recalls-queso-fresco-products-because-possible-health-risk

#queso #elabuelito #riogrande #riolindo #listeria #recall