Dr. Howard Smith Reports

Vidcast:  https://youtu.be/aJjQSnjvQXI

Fewer than 1% of patients recovering from CoVid19 produce the highest concentrations of virus neutralizing antibodies.  A just-published study from New York’s Rockefeller University analyses the antibodies from 149 recovered CoVid patients and controls.

The quantity of CoVid neutralizing IgG antibodies were measured at 39 days following each subject’s onset of symptoms.  The concentration of useful antibody was less than 1:1000 in 79% of subjects.

The conclusion is that most CoVid19 infections induce only a moderate protective antibody response.  They also create T-cell immunity, and we hope that such energized killer cells may confer lasting CoVid immunity.  For now protect yourself with masking, distancing, washing.

https://www.nature.com/articles/s41586-020-2456-9_reference.pdf

#covid #antibodies #covidimmunity

Vidcast:  https://youtu.be/aJjQSnjvQXI

Fewer than 1% of patients recovering from CoVid19 produce the highest concentrations of virus neutralizing antibodies.  A just-published study from New York’s Rockefeller University analyses the antibodies from 149 recovered CoVid patients and controls.

The quantity of CoVid neutralizing IgG antibodies were measured at 39 days following each subject’s onset of symptoms.  The concentration of useful antibody was less than 1:1000 in 79% of subjects.

The conclusion is that most CoVid19 infections induce only a moderate protective antibody response.  They also create T-cell immunity, and we hope that such energized killer cells may confer lasting CoVid immunity.  For now protect yourself with masking, distancing, washing.

https://www.nature.com/articles/s41586-020-2456-9_reference.pdf

#covid #antibodies #covidimmunity

Vidcast:  https://youtu.be/brZGskRn4rc

A large Scottish study now reports that low Vitamin D levels show no association with risk of severe CoVid19 infection or mortality.  Researchers at The University of Glascow just pre-published this conclusion following their analysis of 656 CoVid patient case reports documented the the UK Biobank.

At first glance, the unadjusted numbers suggested that Vitamin D deficiency might trigger a greater susceptibility of CoVid.  A deeper data dive acquitted Vitamin D while indicting advancing age, male gender, socio-economic disadvantage, obesity, and diabetes.

You do want normal Vitamin D levels to maintain strong bones and normal vital organ functioning.  Just know that taking extra will not improve your CoVid odds.

https://www.medrxiv.org/content/10.1101/2020.06.26.20140921v1.full.pdf

#covid #vitamind

Vidcast:  https://youtu.be/brZGskRn4rc

A large Scottish study now reports that low Vitamin D levels show no association with risk of severe CoVid19 infection or mortality.  Researchers at The University of Glascow just pre-published this conclusion following their analysis of 656 CoVid patient case reports documented the the UK Biobank.

At first glance, the unadjusted numbers suggested that Vitamin D deficiency might trigger a greater susceptibility of CoVid.  A deeper data dive acquitted Vitamin D while indicting advancing age, male gender, socio-economic disadvantage, obesity, and diabetes.

You do want normal Vitamin D levels to maintain strong bones and normal vital organ functioning.  Just know that taking extra will not improve your CoVid odds.

https://www.medrxiv.org/content/10.1101/2020.06.26.20140921v1.full.pdf

#covid #vitamind

Vidcast:  https://youtu.be/9wgfNdAQbp4

One in every four air samples from a hospital air handler contained detectable CoVid19 RNA.  University of Oregon investigators report this finding after sampling hospital air at various stages of recirculation and filtration.

A full 35% of samples from pre-filters, where recirculated and outside air entered the system, had viral RNA.  Even with filtration, 20% of samples at outlet air vents were positive.

This typical hospital system can only filter down to a MERV15 specification removing micro-organisms larger than 1 micron but permitting viruses to pass.  As we repopulate public spaces including theaters, restaurants, and airplanes, you will need your own HEPA filtration masks to remain safe. Buy or make them now.

https://www.medrxiv.org/content/10.1101/2020.06.26.20141085v1.full.pdf

#covid #masks #hvac #theaters #airplanes #restaurants

Vidcast:  https://youtu.be/9wgfNdAQbp4

One in every four air samples from a hospital air handler contained detectable CoVid19 RNA.  University of Oregon investigators report this finding after sampling hospital air at various stages of recirculation and filtration.

A full 35% of samples from pre-filters, where recirculated and outside air entered the system, had viral RNA.  Even with filtration, 20% of samples at outlet air vents were positive.

This typical hospital system can only filter down to a MERV15 specification removing micro-organisms larger than 1 micron but permitting viruses to pass.  As we repopulate public spaces including theaters, restaurants, and airplanes, you will need your own HEPA filtration masks to remain safe. Buy or make them now.

https://www.medrxiv.org/content/10.1101/2020.06.26.20141085v1.full.pdf

#covid #masks #hvac #theaters #airplanes #restaurants

Vidcast:  https://youtu.be/oktP81p0wh8

CoVid was detectable in the wastewater of Milan and Turin a full 2 months before the first known case of the novel coronavirus surfaced in Lombardy.  Researchers at the Italian National Institute of Health draw this surprising conclusion after testing wastewater samples from various Italian cities gathered as far back as September, 2018.

The first CoVid-positive samples appeared on December 18th in Milan and Turin and on January 29th in Bologna.  The first Italian case of CoVid was identified in Lombardy on February 21st.

These findings are a testimony to hyper-infectious nature of this disease and to the fact that many are infected without even knowing it.  Mask, distance, wash.

https://www.medrxiv.org/content/10.1101/2020.06.25.20140061v1.full.pdf

#covid #wastewater #italy

Vidcast:  https://youtu.be/oktP81p0wh8

CoVid was detectable in the wastewater of Milan and Turin a full 2 months before the first known case of the novel coronavirus surfaced in Lombardy.  Researchers at the Italian National Institute of Health draw this surprising conclusion after testing wastewater samples from various Italian cities gathered as far back as September, 2018.

The first CoVid-positive samples appeared on December 18th in Milan and Turin and on January 29th in Bologna.  The first Italian case of CoVid was identified in Lombardy on February 21st.

These findings are a testimony to hyper-infectious nature of this disease and to the fact that many are infected without even knowing it.  Mask, distance, wash.

https://www.medrxiv.org/content/10.1101/2020.06.25.20140061v1.full.pdf

#covid #wastewater #italy

Vidcast:  https://youtu.be/lFLL_IWAY4k

When men contract CoVid19, they mount a less robust T cell defense than women, generate more harmful inflammatory cytokines than women, and suffer more severe clinical consequences than women.  These conclusions come from a Yale study of 93 CoVid patients just published by the online pre-print server medrixiv.com.

 The researchers also found that the incidence of poorly protective anti-virus T cell populations and dangerous inflammatory agents increase with advancing age in men but not women.  This adverse immune pattern also increased with excessive body weight in men but not in women.

Bottom line: guys should be extra cautious not to contract the virus.  That means responsible mask wearing, distancing, and washing.

https://www.medrxiv.org/content/10.1101/2020.06.06.20123414v2.full.pdf

#covid #menshealth #tcells #cytokinestorm

Vidcast:  https://youtu.be/lFLL_IWAY4k

When men contract CoVid19, they mount a less robust T cell defense than women, generate more harmful inflammatory cytokines than women, and suffer more severe clinical consequences than women.  These conclusions come from a Yale study of 93 CoVid patients just published by the online pre-print server medrixiv.com.

 The researchers also found that the incidence of poorly protective anti-virus T cell populations and dangerous inflammatory agents increase with advancing age in men but not women.  This adverse immune pattern also increased with excessive body weight in men but not in women.

Bottom line: guys should be extra cautious not to contract the virus.  That means responsible mask wearing, distancing, and washing.

https://www.medrxiv.org/content/10.1101/2020.06.06.20123414v2.full.pdf

#covid #menshealth #tcells #cytokinestorm