Dr. Howard Smith Reports

Vidcast:  https://youtu.be/-s0aMlSb4Xc

Oriahnn, a estrogen-progestin combo pharmaceutical, may now be prescribed for management of excessive menstrual bleed caused by fibroids of the uterus.  The two clinical trials of this oral medication revealed that the drug reduced bleeding between 7 and 8 fold.  This drug provides a non-surgical alternative to removal of the uterus for those women who may not desire or qualify to have the operation.  The chief, serious complications of Oriahnn use include a reduction in bone density and an increased risk of fractures and an increased risk of excessive blood clotting with heart attack or stroke.  Women with known osteoporosis, a smoking habit, or high blood pressure should consider other avenues of therapy.  This drug will not prevent pregnancy, and non-hormonal contraception should be employed.

https://www.fda.gov/news-events/press-announcements/fda-approves-new-option-treat-heavy-menstrual-bleeding-associated-fibroids-women

#approval #fda #oriahnn #fibroids #metrorrhagia

Vidcast:  https://youtu.be/-s0aMlSb4Xc

Oriahnn, a estrogen-progestin combo pharmaceutical, may now be prescribed for management of excessive menstrual bleed caused by fibroids of the uterus.  The two clinical trials of this oral medication revealed that the drug reduced bleeding between 7 and 8 fold.  This drug provides a non-surgical alternative to removal of the uterus for those women who may not desire or qualify to have the operation.  The chief, serious complications of Oriahnn use include a reduction in bone density and an increased risk of fractures and an increased risk of excessive blood clotting with heart attack or stroke.  Women with known osteoporosis, a smoking habit, or high blood pressure should consider other avenues of therapy.  This drug will not prevent pregnancy, and non-hormonal contraception should be employed.

https://www.fda.gov/news-events/press-announcements/fda-approves-new-option-treat-heavy-menstrual-bleeding-associated-fibroids-women

#approval #fda #oriahnn #fibroids #metrorrhagia

Vidcast:  https://youtu.be/XU_CHhXXy44

Masks, eye protection and physical distancing each seem to have about equal impact on reducing your risk of a coronavirus infection.  Researchers at Canada’s McMaster University performed a global meta-analysis of 172 studies covering 25,697 patients.

While wearing face masks reduced the risk of infection the most, some 14%, eye protection reduced that risk 11% and distancing reduced the risk 9.8%. The fact that shielding your eyes helps so much emphasizes the importance of airborne virus transmission.

If you are in locations with abundant virus, do wear goggles, a face shield, or attachments to your glasses that block side entry of aerosols.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31142-9/fulltext

#covid #eyes #distancing #masks #goggles #faceshield

Vidcast:  https://youtu.be/XU_CHhXXy44

Masks, eye protection and physical distancing each seem to have about equal impact on reducing your risk of a coronavirus infection.  Researchers at Canada’s McMaster University performed a global meta-analysis of 172 studies covering 25,697 patients.

While wearing face masks reduced the risk of infection the most, some 14%, eye protection reduced that risk 11% and distancing reduced the risk 9.8%. The fact that shielding your eyes helps so much emphasizes the importance of airborne virus transmission.

If you are in locations with abundant virus, do wear goggles, a face shield, or attachments to your glasses that block side entry of aerosols.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31142-9/fulltext

#covid #eyes #distancing #masks #goggles #faceshield

Vidcast:  https://youtu.be/aOyTd1xJVy0

Not all forms of HCQ or CQ are created equal..  A Chinese study just published by the online pre-print server biorxiv.org reopens the HCQ/CQ controversy with a bit of sophisticated organic chemistry.

Clinically available hydroxychloroquine is a blend of two mirror images of the same molecule, the left and right enantiomers.  The study shows that L-HCQ inhibits CoVid replication 60% better than the R-HCQ.  L-CQ is 27% more effective than R-CQ. 

The mixed HCQ and CQ does’t help CoVid patients.   If these findings are confirmed by other investigators, cautious clinical studies might show that the lefty versions do.

https://www.biorxiv.org/content/10.1101/2020.05.26.114033v2.full.pdf

#covid #hcq #hydroxchloroquine #cq #enantiomers #distereoisomers

Vidcast:  https://youtu.be/aOyTd1xJVy0

Not all forms of HCQ or CQ are created equal..  A Chinese study just published by the online pre-print server biorxiv.org reopens the HCQ/CQ controversy with a bit of sophisticated organic chemistry.

Clinically available hydroxychloroquine is a blend of two mirror images of the same molecule, the left and right enantiomers.  The study shows that L-HCQ inhibits CoVid replication 60% better than the R-HCQ.  L-CQ is 27% more effective than R-CQ. 

The mixed HCQ and CQ does’t help CoVid patients.   If these findings are confirmed by other investigators, cautious clinical studies might show that the lefty versions do.

https://www.biorxiv.org/content/10.1101/2020.05.26.114033v2.full.pdf

#covid #hcq #hydroxchloroquine #cq #enantiomers #distereoisomers

Vidcast:  https://youtu.be/2EiQ8xgDXQs

Singapore’s Health Ministry, now facing a resurgence of CoVid19 cases, rejects face shields alone as insufficient protection against transmitting or contracting coronavirus.  The official guidance statement underscores the fact that air gaps around face shield permit contaminated droplets and aerosols to travel freely.

The only persons permitted to wear face shields are: 

1. Children 12 and under who cannot wear masks.  I’ve seen kids as young as 2 wearing them well.
2. Persons who cannot breathe through a mask.
3. Persons speaking to a group at a safe distance from listeners.

 Wearing a face shield over a mask does provide additional protection.  CoVid19 is dangerous.  Avoid it with MDW: masks, distancing, washing.

https://www.moh.gov.sg/news-highlights/details/guidance-for-use-of-masks-and-face-shields

#faceshields #masks #covid #pandemic #singapore

Vidcast:  https://youtu.be/2EiQ8xgDXQs

Singapore’s Health Ministry, now facing a resurgence of CoVid19 cases, rejects face shields alone as insufficient protection against transmitting or contracting coronavirus.  The official guidance statement underscores the fact that air gaps around face shield permit contaminated droplets and aerosols to travel freely.

The only persons permitted to wear face shields are: 

1. Children 12 and under who cannot wear masks.  I’ve seen kids as young as 2 wearing them well.
2. Persons who cannot breathe through a mask.
3. Persons speaking to a group at a safe distance from listeners.

 Wearing a face shield over a mask does provide additional protection.  CoVid19 is dangerous.  Avoid it with MDW: masks, distancing, washing.

https://www.moh.gov.sg/news-highlights/details/guidance-for-use-of-masks-and-face-shields

#faceshields #masks #covid #pandemic #singapore

Vidcast:  https://youtu.be/huM7v68jnQg

Closing schools turns out to be the single best non-pharmaceutical way to halt CoVid.  This the conclusion of an international collaborative meta-analysis by university number crunchers in the US, UK, Canada and Australia.

The data from 41 countries show that school closings have a 58% effectiveness, restricting gatherings to 10 or fewer 24%,  closing non-essential businesses 23%,

closing high risk businesses 19%, testing those with respiratory symptoms 18%, and stay at home orders 17%.

We have a dilemma: kids attending school then bring CoVid home and transmit it to multiple generations including the vulnerable.   Yet closed schools equals closed workplaces.  The solution: testing all children and their contacts.

https://www.medrxiv.org/content/10.1101/2020.05.28.20116129v1.full.pdf

#covid #schools #children #work #testing

Vidcast:  https://youtu.be/huM7v68jnQg

Closing schools turns out to be the single best non-pharmaceutical way to halt CoVid.  This the conclusion of an international collaborative meta-analysis by university number crunchers in the US, UK, Canada and Australia.

The data from 41 countries show that school closings have a 58% effectiveness, restricting gatherings to 10 or fewer 24%,  closing non-essential businesses 23%,

closing high risk businesses 19%, testing those with respiratory symptoms 18%, and stay at home orders 17%.

We have a dilemma: kids attending school then bring CoVid home and transmit it to multiple generations including the vulnerable.   Yet closed schools equals closed workplaces.  The solution: testing all children and their contacts.

https://www.medrxiv.org/content/10.1101/2020.05.28.20116129v1.full.pdf

#covid #schools #children #work #testing