Dr. Howard Smith Reports

Vidcast:  https://youtu.be/wEDQ78_nlZU

Hydroxychloroquine with added azithromycin (Zithromax) eradicates CoVid19 virus in the blood of infected patients even better than hydroxychlorquine alone.  A pre-published preliminary French study followed 36 CoVid19 patients hospitalized for treatment in Marseilles.

14 patients received hydroxychloroquine 600 mg/d alone and 6 of them also received treatment with a Z-pack. The data revealed a significant drop in nasal virus over a 5 day period.  By that time, only 50% of hydroxychloroquine-treated patients had virus and none of those treated with both drugs had it.

This news is exciting but not established fact.  These drugs each have side effects, some deadly, and must be careful monitored.

https://doi.org/10.1016/j.ijantimicag.2020.105949

#covid19 #coronavirus #hydroxychloroquine #azithromycin #zithromax

Vidcast:  https://youtu.be/wEDQ78_nlZU

Hydroxychloroquine with added azithromycin (Zithromax) eradicates CoVid19 virus in the blood of infected patients even better than hydroxychlorquine alone.  A pre-published preliminary French study followed 36 CoVid19 patients hospitalized for treatment in Marseilles.

14 patients received hydroxychloroquine 600 mg/d alone and 6 of them also received treatment with a Z-pack. The data revealed a significant drop in nasal virus over a 5 day period.  By that time, only 50% of hydroxychloroquine-treated patients had virus and none of those treated with both drugs had it.

This news is exciting but not established fact.  These drugs each have side effects, some deadly, and must be careful monitored.

https://doi.org/10.1016/j.ijantimicag.2020.105949

#covid19 #coronavirus #hydroxychloroquine #azithromycin #zithromax

Vidcast:  https://youtu.be/Pi8bv4AhqMk

Hydroxychloroquine definitely helps eradicate severe novel coronavirus infections.  This is the conclusion of a randomized Wuhan University study looking at 62 hospitalized CoVid19 patients that was just pre-published online.

Those in the experimental group received hydroxychloroquine 400 mg/day in additional to conventional medical and respiratory therapy.  Those receiving the med were 47% more likely to clear their pneumonia and enjoy faster temperature normalization.  The only 4 patients who deteriorated during the study did not receive hydroxychloroquine.

Preliminary studies like this give us hope that there are weapons we can use against this virus.  The drug may help in desperate cases and further study may support more widespread use.

https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v2.full.pdf

#covid19 #coronavirus #hydroxychloroquine

Vidcast:  https://youtu.be/Pi8bv4AhqMk

Hydroxychloroquine definitely helps eradicate severe novel coronavirus infections.  This is the conclusion of a randomized Wuhan University study looking at 62 hospitalized CoVid19 patients that was just pre-published online.

Those in the experimental group received hydroxychloroquine 400 mg/day in additional to conventional medical and respiratory therapy.  Those receiving the med were 47% more likely to clear their pneumonia and enjoy faster temperature normalization.  The only 4 patients who deteriorated during the study did not receive hydroxychloroquine.

Preliminary studies like this give us hope that there are weapons we can use against this virus.  The drug may help in desperate cases and further study may support more widespread use.

https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v2.full.pdf

#covid19 #coronavirus #hydroxychloroquine

Vidcast:  https://youtu.be/lPZiZXc-JNA

Angiotensin receptor blockers and Ace inhibitor anti-hypertensive medications may actually help coronavirus victims fighting for their lives.  Several weeks ago I reported studies that questioned the safety of such drugs since the virus appears to interact with the angiotensin system.  

 A pre-published Chinese study looked at 126  CoVid19 patients treated with angiotensin drugs versus other blood pressure medications.  The new data reveals that those patients treated with angiotensin-type drugs demonstrate 42% less harmful inflammation, tend to suffer critical disease progression 41% less often, and have a 35% lower death rate.

As we learn more about this brand new coronavirus, treatment guidance changes.  That’s medical science for you.

https://www.medrxiv.org/content/10.1101/2020.03.31.20038935v1.full.pdf 

#covid19 #covid19 #hypertension #angiotensin #arb #aceinhibitor

Vidcast:  https://youtu.be/lPZiZXc-JNA

Angiotensin receptor blockers and Ace inhibitor anti-hypertensive medications may actually help coronavirus victims fighting for their lives.  Several weeks ago I reported studies that questioned the safety of such drugs since the virus appears to interact with the angiotensin system.  

 A pre-published Chinese study looked at 126  CoVid19 patients treated with angiotensin drugs versus other blood pressure medications.  The new data reveals that those patients treated with angiotensin-type drugs demonstrate 42% less harmful inflammation, tend to suffer critical disease progression 41% less often, and have a 35% lower death rate.

As we learn more about this brand new coronavirus, treatment guidance changes.  That’s medical science for you.

https://www.medrxiv.org/content/10.1101/2020.03.31.20038935v1.full.pdf 

#covid19 #covid19 #hypertension #angiotensin #arb #aceinhibitor

Vidcast:  https://youtu.be/y3gQk50l2eA

An extra 3-400 calories a day restores predictable periods for exercising women.  A study from Penn State to be presented to the Endocrine Society’s annual meeting studied 62 fitness enthusiasts with sporadic menstrual periods.

Half of the group increased their daily calories.  They and the control group continued their vigorous exercise and the remainder of their usual diet over the 12 month study duration.  Those women who added calories were twice as likely to achieve menstrual regularity.

Women with eating disorders such as anorexia-bulemia suffer radically altered menstrual cycles with their weight loss.  Now we know that even those with regular diets may benefit from a few more calories.

https://www.sciencedaily.com/releases/2020/03/200331093259.htm

#calories #dysmenorrhea #exercise

Vidcast:  https://youtu.be/y3gQk50l2eA

An extra 3-400 calories a day restores predictable periods for exercising women.  A study from Penn State to be presented to the Endocrine Society’s annual meeting studied 62 fitness enthusiasts with sporadic menstrual periods.

Half of the group increased their daily calories.  They and the control group continued their vigorous exercise and the remainder of their usual diet over the 12 month study duration.  Those women who added calories were twice as likely to achieve menstrual regularity.

Women with eating disorders such as anorexia-bulemia suffer radically altered menstrual cycles with their weight loss.  Now we know that even those with regular diets may benefit from a few more calories.

https://www.sciencedaily.com/releases/2020/03/200331093259.htm

#calories #dysmenorrhea #exercise

Vidcast:  https://youtu.be/VcVf5kR2QAA

Some good news to brighten your day.  A new cancer screening test from Harvard’s Dana-Farber Cancer Institute and the Mayo Clinic can detect the presence of more than 50 cancer types including the tough ones to diagnose like ovarian and pancreatic cancer.

The test detects cancer DNA in the blood and differentiates it from normal DNA by patterns of methylation.  It can pinpoint the source of the cancer organ-wise in more than 90% of cases.

More work must be done since, currently, the test can only detect cancer 43% of the time.  If a cancer is detected, the test is correct 99% of the time.   Very exciting.  Stay tuned.

M.C. Liu, G.R. Oxnard, E.A. Klein, etal. Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. Annals of Oncology, 2020; DOI: 10.1016/j.annonc.2020.02.011

#cancer #ovarian #pancreatic #cancertest #dna

Vidcast:  https://youtu.be/VcVf5kR2QAA

Some good news to brighten your day.  A new cancer screening test from Harvard’s Dana-Farber Cancer Institute and the Mayo Clinic can detect the presence of more than 50 cancer types including the tough ones to diagnose like ovarian and pancreatic cancer.

The test detects cancer DNA in the blood and differentiates it from normal DNA by patterns of methylation.  It can pinpoint the source of the cancer organ-wise in more than 90% of cases.

More work must be done since, currently, the test can only detect cancer 43% of the time.  If a cancer is detected, the test is correct 99% of the time.   Very exciting.  Stay tuned.

M.C. Liu, G.R. Oxnard, E.A. Klein, etal. Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. Annals of Oncology, 2020; DOI: 10.1016/j.annonc.2020.02.011

#cancer #ovarian #pancreatic #cancertest #dna