Dr. Howard Smith Reports

Vidcast:  https://youtu.be/x3Xy--faEb4

Sun Hong Foods of Montebello, CA is recalling its Enoki Mushrooms.  This product may be contaminated with Listeria monocytogenes.  Listeria causes serious, sometimes life-threatening illness in the young, old, ill, or immune-compromised.  The product was sold in CA, TX, OR, WA, TX, IL FL.  

Return the product to the point of purchase or call the company at 1-323-597-1112.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/sun-hong-foods-inc-recalls-enoki-mushroom-because-possible-health-risk

#recall #mushrooms #listeria

Vidcast:  https://youtu.be/x3Xy--faEb4

Sun Hong Foods of Montebello, CA is recalling its Enoki Mushrooms.  This product may be contaminated with Listeria monocytogenes.  Listeria causes serious, sometimes life-threatening illness in the young, old, ill, or immune-compromised.  The product was sold in CA, TX, OR, WA, TX, IL FL.  

Return the product to the point of purchase or call the company at 1-323-597-1112.

https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/sun-hong-foods-inc-recalls-enoki-mushroom-because-possible-health-risk

#recall #mushrooms #listeria

Vidcast:  https://youtu.be/IGrRPbKKB2U

The veteran MAO inhibitor phenelzine, branded as Nardil, may help control recurrent prostatic cancer.  Oncologists at USC studied 20 prostatic cancer patients with persistently elevated levels of prostate-specific antigen, PSA, following definitive surgery or radiation therapy for prostatic cancer.

The men were treated with phenelzine 30 mg twice daily for 3 months.  Results showed that 24% had PSA drops of more than 30% and 6% had drops of more than 50%.  The downsides of treatment include dizziness and blood pressure elevation. 

Mono-amine oxidase inhibitors block androgen receptor function and prostate cancer growth.  This drug may help fight this second most common cancer in men when other treatment fails.

Mitchell E. Gross, David B. Agus, Tanya B. Dorff, Jacek K. Pinski, David I. Quinn, Olga Castellanos, Patrick Gilmore, Jean C. Shih. Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer. Prostate Cancer and Prostatic Diseases, 2020; DOI: 10.1038/s41391-020-0211-9

#prostatecancer #maoinhibitor #phenelzine #nardil

Vidcast:  https://youtu.be/IGrRPbKKB2U

The veteran MAO inhibitor phenelzine, branded as Nardil, may help control recurrent prostatic cancer.  Oncologists at USC studied 20 prostatic cancer patients with persistently elevated levels of prostate-specific antigen, PSA, following definitive surgery or radiation therapy for prostatic cancer.

The men were treated with phenelzine 30 mg twice daily for 3 months.  Results showed that 24% had PSA drops of more than 30% and 6% had drops of more than 50%.  The downsides of treatment include dizziness and blood pressure elevation. 

Mono-amine oxidase inhibitors block androgen receptor function and prostate cancer growth.  This drug may help fight this second most common cancer in men when other treatment fails.

Mitchell E. Gross, David B. Agus, Tanya B. Dorff, Jacek K. Pinski, David I. Quinn, Olga Castellanos, Patrick Gilmore, Jean C. Shih. Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer. Prostate Cancer and Prostatic Diseases, 2020; DOI: 10.1038/s41391-020-0211-9

#prostatecancer #maoinhibitor #phenelzine #nardil

Vidcast:  https://youtu.be/cFniiZPEYsE

Warmer, drier weather in late spring and summer will only slow the coronavirus epidemic by some 18%.  This conclusion stems from a detailed study of CoVid19 infection spread in mainland China provinces that differ from each other in terms of average temperature, humidity, wind, and precipitation.

Only a rise in average temperature and a drop in average  humidity slow CoVid19 disease spread, and the effect is small.   Eighty-two percent of viral disease containment and mitigation must come from other measures.

Bottom line: don’t believe that balmy weather will protect you from coronavirus.  Only you can do that by obsessive hand washing, not touching your face, social isolation, and healthy lifestyles.

https://www.medrxiv.org/content/10.1101/2020.03.05.20031872v1.full.pdf

#covid19 #temperature #humidity #spring #summer

Vidcast:  https://youtu.be/cFniiZPEYsE

Warmer, drier weather in late spring and summer will only slow the coronavirus epidemic by some 18%.  This conclusion stems from a detailed study of CoVid19 infection spread in mainland China provinces that differ from each other in terms of average temperature, humidity, wind, and precipitation.

Only a rise in average temperature and a drop in average  humidity slow CoVid19 disease spread, and the effect is small.   Eighty-two percent of viral disease containment and mitigation must come from other measures.

Bottom line: don’t believe that balmy weather will protect you from coronavirus.  Only you can do that by obsessive hand washing, not touching your face, social isolation, and healthy lifestyles.

https://www.medrxiv.org/content/10.1101/2020.03.05.20031872v1.full.pdf

#covid19 #temperature #humidity #spring #summer

Vidcast:  https://youtu.be/ubLCDxZ-sTI

The CoVid19 could be transmitted person-to-person via a fecal-oral route as well as by respiratory secretions.  A group of 73 Chinese patients testing positive for respiratory CoVid19 were checked for viral RNA in stool.

Just over half of the infected patients had CoVid19 in their fecal material.  Longitudinal testing revealed that 23% of those continued to show evidence of virus in the gastrointestinal tract even after their respiratory samples turned negative.

This study emphasizes the importance of obsessive cleanliness and repeated handwashing particularly after contacting surfaces in public places, especially public restrooms.  Soap and water for 20 seconds is best, and alcohol hand sanitizers a runner-up.

Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H, Evidence for gastrointestinal infection of SARS-CoV-2, Gastroenterology (2020), doi: https://doi.org/10.1053/j.gastro.2020.02.055.

#covid19 #coronavirus #fecal #fecaloral

Vidcast:  https://youtu.be/ubLCDxZ-sTI

The CoVid19 could be transmitted person-to-person via a fecal-oral route as well as by respiratory secretions.  A group of 73 Chinese patients testing positive for respiratory CoVid19 were checked for viral RNA in stool.

Just over half of the infected patients had CoVid19 in their fecal material.  Longitudinal testing revealed that 23% of those continued to show evidence of virus in the gastrointestinal tract even after their respiratory samples turned negative.

This study emphasizes the importance of obsessive cleanliness and repeated handwashing particularly after contacting surfaces in public places, especially public restrooms.  Soap and water for 20 seconds is best, and alcohol hand sanitizers a runner-up.

Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H, Evidence for gastrointestinal infection of SARS-CoV-2, Gastroenterology (2020), doi: https://doi.org/10.1053/j.gastro.2020.02.055.

#covid19 #coronavirus #fecal #fecaloral

Vidcast:  https://youtu.be/gCXknzkakOU

This novel coronavirus is not transmitted from mother to infant during late-term pregnancy.  British investigators studied 19 pregnant women infected with CoVid19 within 2 weeks of delivery.

Of the 19 women, 84% were symptomatic with disease.   One woman required critical care; there were no maternal deaths.  89% were delivered by c-section and 42% were pre-term deliveries with a mean gestational age of 36.5 weeks. 

No CoVid19 was found in amniotic fluid, cord blood, breastmilk, or neonatal throat samples.  This lack of vertical transmission is similar to studies of SARS and MERS during pregnancy.

This tiny, preliminary study is heartening.  More studies of women infected earlier in gestation must now be completed.

https://www.medrxiv.org/content/10.1101/2020.03.06.20032144v1.full.pdf

#covid19 #coronavirus #pregnancy #verticaltransmission

Vidcast:  https://youtu.be/gCXknzkakOU

This novel coronavirus is not transmitted from mother to infant during late-term pregnancy.  British investigators studied 19 pregnant women infected with CoVid19 within 2 weeks of delivery.

Of the 19 women, 84% were symptomatic with disease.   One woman required critical care; there were no maternal deaths.  89% were delivered by c-section and 42% were pre-term deliveries with a mean gestational age of 36.5 weeks. 

No CoVid19 was found in amniotic fluid, cord blood, breastmilk, or neonatal throat samples.  This lack of vertical transmission is similar to studies of SARS and MERS during pregnancy.

This tiny, preliminary study is heartening.  More studies of women infected earlier in gestation must now be completed.

https://www.medrxiv.org/content/10.1101/2020.03.06.20032144v1.full.pdf

#covid19 #coronavirus #pregnancy #verticaltransmission