Dr. Howard Smith Reports

Vidcast:  https://youtu.be/JhQ4qo4s5cE

• Moderna Therapeutics, Cambridge, MA has shipped first batches of its CoVid19 vaccine to be used for clinical testing in April.  This vaccine was developed using a cutting edge genetic method employing messengerRNA that codes for Coronavirus proteins.  The mRNA triggers lymph node production of immune cells that attack the virus.  It will require a year of trials and testing before we have a usable vaccine.
• Other vaccines are in development: Novavax using spike protein as antigen; Sanofi Pasteur with work with US government; Takes and Evvivax in Italy.

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30079-5/fulltext

#covid19 #coronavirus #epidemic #pandemic #vaccine

Vidcast:  https://youtu.be/JhQ4qo4s5cE

• Moderna Therapeutics, Cambridge, MA has shipped first batches of its CoVid19 vaccine to be used for clinical testing in April.  This vaccine was developed using a cutting edge genetic method employing messengerRNA that codes for Coronavirus proteins.  The mRNA triggers lymph node production of immune cells that attack the virus.  It will require a year of trials and testing before we have a usable vaccine.
• Other vaccines are in development: Novavax using spike protein as antigen; Sanofi Pasteur with work with US government; Takes and Evvivax in Italy.

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30079-5/fulltext

#covid19 #coronavirus #epidemic #pandemic #vaccine

Vidcast:  https://youtu.be/0b73wWtxkJo

• One case report of viral transfer from an asymptomatic carrier in China.  Five family members contracted the disease from a a person who had been in Wuhan.
• Case series from Wuhan: 710 total with disease; 7.3% critically ill: 2/3s men; non-survivors were older, had other illness.
• Larger  case series just in from Wuhan: total of  44, 672 confirmed cases: 81% were mild,  14% were severe, 5% critical; overall case fatality rate of 2.3%; almost twice as high in men;  none among those with mild cases but 49% among those in critical condition; 0.2% 0-40 years, 1.3% in 50s, 3.6% in 60s, 8% in 70s, and 14.8% 80+; first recognition of CoVid19 cases on 12/31/2019, epidemic peaked January 23-26, 2019
• Rate of Chinese CoVid incidence is diminishing. (graph)

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30079-5/fulltext

https://bit.ly/2Tan9mm

https://www.nytimes.com/2020/02/27/world/asia/coronavirus-treament-recovery.html

#covid19 #coronavirus #epidemic #pandemicm #china

Vidcast:  https://youtu.be/0b73wWtxkJo

• One case report of viral transfer from an asymptomatic carrier in China.  Five family members contracted the disease from a a person who had been in Wuhan.
• Case series from Wuhan: 710 total with disease; 7.3% critically ill: 2/3s men; non-survivors were older, had other illness.
• Larger  case series just in from Wuhan: total of  44, 672 confirmed cases: 81% were mild,  14% were severe, 5% critical; overall case fatality rate of 2.3%; almost twice as high in men;  none among those with mild cases but 49% among those in critical condition; 0.2% 0-40 years, 1.3% in 50s, 3.6% in 60s, 8% in 70s, and 14.8% 80+; first recognition of CoVid19 cases on 12/31/2019, epidemic peaked January 23-26, 2019
• Rate of Chinese CoVid incidence is diminishing. (graph)

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30079-5/fulltext

https://bit.ly/2Tan9mm

https://www.nytimes.com/2020/02/27/world/asia/coronavirus-treament-recovery.html

#covid19 #coronavirus #epidemic #pandemicm #china

Vidcast:  https://youtu.be/ll7Qe3Mp8Vw

Published on 2/26/2020 and data not updated since 2/21/2020:

• Total confirmed cases: 60
• Travel-related: 12
• Person-To-Person: 2
• Community: 1
• Repatriated US Citizens
• • From China: 3
  • From Diamond Princess Cruise Ship: 42
• Total Tested: 445

https://www.cdc.gov/coronavirus/2019-ncov/

#covid19 #coronavirus #epidemic #pandemic #cdc

Vidcast:  https://youtu.be/ll7Qe3Mp8Vw

Published on 2/26/2020 and data not updated since 2/21/2020:

• Total confirmed cases: 60
• Travel-related: 12
• Person-To-Person: 2
• Community: 1
• Repatriated US Citizens
• • From China: 3
  • From Diamond Princess Cruise Ship: 42
• Total Tested: 445

https://www.cdc.gov/coronavirus/2019-ncov/

#covid19 #coronavirus #epidemic #pandemic #cdc

Vidcast:  https://youtu.be/6r9TeuoT8rA

• Bloomberg News:  As of 2/28/2020, 8:40 AM
• Worldwide cases: 83,810; Worldwide Deaths.: 2870.
• Latest country by country from coronavirus.video:
• China: Cases: 78824 Deaths: 2788.
• S. Korea: Cases: 2022 Deaths: 13.
• Italy: Cases: 655 Deaths: 17.
• Iran: Cases: 245 Deaths: 21.
• Japan: Cases: 214 Deaths: 4.

#covid19 #coronavirus #epidemic #pandemi

https://www.bloomberg.com/graphics/2020-wuhan-novel-coronavirus-outbreak/

https://www.coronavirus.video/country-stats.php

Vidcast:  https://youtu.be/6r9TeuoT8rA

• Bloomberg News:  As of 2/28/2020, 8:40 AM
• Worldwide cases: 83,810; Worldwide Deaths.: 2870.
• Latest country by country from coronavirus.video:
• China: Cases: 78824 Deaths: 2788.
• S. Korea: Cases: 2022 Deaths: 13.
• Italy: Cases: 655 Deaths: 17.
• Iran: Cases: 245 Deaths: 21.
• Japan: Cases: 214 Deaths: 4.

#covid19 #coronavirus #epidemic #pandemi

https://www.bloomberg.com/graphics/2020-wuhan-novel-coronavirus-outbreak/

https://www.coronavirus.video/country-stats.php

Vidcast:  https://youtu.be/zIBhW8YLjwg

Broccoli and its cruciferous vegetable cousins can inactivate a gene that cancers use to overwhelm our immune systems and our bodies.  This latest finding comes from Boston’s Beth Israel Deaconness Medical Center’s Cancer Research Institute.

We know that eating broccoli, cauliflower, cabbage, collard greens, Brussel sprouts, and kale seems to reduce the risk of cancer.  The Harvard researchers report that a tiny molecule in these vegetables, indole 3 carbinol or I3C, blocks one gene, WWP1, and releases a second gene, PTEN that is a potent human cancer cell suppressor.  By this round about mechanism, these veggies metabolically disable tumor cells.

So all we have so do is eat some broccoli, cauliflower, or cabbage to cure cancer.  No so fast.  Only tiny amounts of the magic I3C are in the usual servings of these vegetables, so you’d have to consume whopping quantities to consistently have an effect.  

Nonetheless, eating them regularly is beneficial while researchers find a way to produce or extract larger quantities of this cancer Achille’s heel.

Yu-Ru Lee, Ming Chen, Jonathan D. Lee, etal. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science, 2019; 364 (6441): eaau0159 DOI: 10.1126/science.aau0159

#broccoli #cancer #cauliflower #cabbage #collardgreens #brusselsprouts #kale #wwpi #pten #indole3carbinol

Vidcast:  https://youtu.be/zIBhW8YLjwg

Broccoli and its cruciferous vegetable cousins can inactivate a gene that cancers use to overwhelm our immune systems and our bodies.  This latest finding comes from Boston’s Beth Israel Deaconness Medical Center’s Cancer Research Institute.

We know that eating broccoli, cauliflower, cabbage, collard greens, Brussel sprouts, and kale seems to reduce the risk of cancer.  The Harvard researchers report that a tiny molecule in these vegetables, indole 3 carbinol or I3C, blocks one gene, WWP1, and releases a second gene, PTEN that is a potent human cancer cell suppressor.  By this round about mechanism, these veggies metabolically disable tumor cells.

So all we have so do is eat some broccoli, cauliflower, or cabbage to cure cancer.  No so fast.  Only tiny amounts of the magic I3C are in the usual servings of these vegetables, so you’d have to consume whopping quantities to consistently have an effect.  

Nonetheless, eating them regularly is beneficial while researchers find a way to produce or extract larger quantities of this cancer Achille’s heel.

Yu-Ru Lee, Ming Chen, Jonathan D. Lee, etal. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science, 2019; 364 (6441): eaau0159 DOI: 10.1126/science.aau0159

#broccoli #cancer #cauliflower #cabbage #collardgreens #brusselsprouts #kale #wwpi #pten #indole3carbinol