Vidcast:  https://www.instagram.com/p/C5Yi-giLgET/

The Consumer Product Safety Commission and Polaris Industries are recalling Model Year 2022-2023 Snowmobiles equipped with PATRIOT BOOST Engines.  The fuel lines of these engines leak creating fire and burn hazards.

About 7,000 of these snowmobiles were sold in the US and about 3,100 were sold in Canada.  Remember too that these snowmobiles have been recalled in February 2022, August 2022, November 2022, May 2023, and August 2023.

Stop fueling and riding these snowmobiles and contact Polaris or a Polaris dealer to schedule a free fuel line inspection and repair.  Reach Polaris at 1-800-765-2747 for more information.

https://www.cpsc.gov/Recalls/2024/Polaris-Recalls-Snowmobiles-Equipped-with-PATRIOT-BOOST-Engines-Due-to-Fire-Hazard-Recall-Alert

#polaris #snowmobile #fuelline #leakage #fire #burns #recall 

Vidcast:  https://www.instagram.com/p/C5Yh_MUrvvA/

The Consumer Product Safety Commission and Forias Direct as recalling Forias pack and play mattresses.  This memory foam mattress violates multiple federal safety standards for crib mattresses including thickness and labeling.  The mattress creates suffocation hazards.

About 1900 of these crib mattresses have been sold at amazon.com.

Stop using these crib mattresses. Cut the mattress in half and send a photo to [email protected] and receive a full refund. 

https://www.cpsc.gov/Recalls/2024/Forias-Pack-and-Play-Mattresses-Recalled-Due-to-Suffocation-Hazard-for-Infants-Violations-of-the-Federal-Safety-Regulation-for-Crib-Mattresses-Sold-Exclusively-on-Amazon-com-by-Forias-Direct-Recall-Alert

#forias #crib #packandplay #mattress #thickness #labeling #suffocation #recall

Vidcast: https://www.instagram.com/p/C5WwxNsrj1h/

The next generation of Moderna’s mRNA CoVid vaccines will be directed against two key portions of the virus’ spike protein rather than the entire spike.  Creating mRNA that codes only for the spike’s N-terminal domain (NTD) and the receptor binding domain (RBD) generates blocking antibodies against these two spike regions that play the greatest roles in viral attachment to human cells.  As a result, this improved vaccine will be more active against variants and subvariants that pop up.

The other good news about this new vaccine family, dubbed mRNA-1283 in contrast to the initial Moderna offering labeled mRNA 1273, is that it offers enhanced stability in the refrigerator vs. the freezer.  In addition, the new vaccine is effective at lower doses with fewer potential side effects.

Look for this new Moderna offering in the fall.

https://medicalxpress.com/news/2023-09-moderna-reveals-highly-covid-vaccine.html

#moderna #CoVid #vaccine #mRNA #NTD #RBD #stability

Vidcast: 

https://www.instagram.com/p/C5Wu4hYLn2O/

The FDA is now out with a warning about skin creams sold for use after tattooing, piercings, laser hair removal, and dermabrasion.  Most of these agents contain the local anesthetic lidocaine in concentrations that are dangerous. The FDA warns that using agents with lidocaine concentrations above 4% is dangerous.

The agency has fired off cease and desist warning letters to 6 companies.

The companies and their dangerous products include:

In general, avoid lidocaine products more concentrated than 4%, don’t use them on injured skin, and don’t wrap the skin with plastic coverings after applying the medications.  High concentrations of lidocaine in the bloodstream causes arrhythmias, seizures, and respiratory problems.

https://www.fda.gov/news-events/press-announcements/fda-warns-consumers-avoid-certain-topical-pain-relief-products-due-potential-dangerous-health

#topical #analgesics #lidocaine #tattoo #piercing #dermabrasion #hairremoval

Vidcast:  https://www.instagram.com/p/C5WuKsELOVL/

Fire-inhibiting and disinfecting compounds, both of which are commonly found around our homes, damage the specialized cells that create the insulating coverings around nerves called myelin sheaths.  The absence of these sheaths is associated with multiple sclerosis.

Case Western Reserve investigators have demonstrated that organophosphate flame retardants found in furniture and electronics stop the maturation of the sheath-generating oligodendrite cells while the quinaternary ammonium compounds found in disinfectants and in personal care products are frankly damaging to such cells.  Epidemiologic analyses indicate that these chemicals and the toxicity they induce are also associated with neurodevelopmental pathology including attention-deficit and autism spectrum disorders.

The take away: pregnant women and young children should not be exposed to these agents.  Read product labels carefully.

https://www.nature.com/articles/s41593-024-01599-2

#flameretardants #disinfectives #myelin #oligodentrites #autism #hyperactivity

Vidcast:  https://www.instagram.com/p/C5WtXOXLVfJ/

It may soon be possible to diagnose not only Parkinson’s but other degenerative neurologic disorders with simple skin biopsies.  This the promise suggested by a new study from Harvard-Beth Israel Hospital neurologists.

Parkinson’s Disease, Lewy body dementia, multiple system atrophy, and pure autonomic failure are neurologic disorders with a distinctive deposit of the compound phosphorylated alpha-synuclein (P-synuclein) in tissues throughout the nervous system.  The Harvard study evaluated the practicality of detecting this telltale compound in simple skin biopsies.

After evaluating leg, thigh and neck skin samples from 428 individuals with these neurologic disorders, the data demonstrated the presence of P-synuclein in 93% of those with Parkinson’s, 96% of those with Lewy body dementia, 98% of those with multiple system atrophy, and 100% of those with pure autonomic failure.

New studies are underway to validate the usefulness of P-synuclein skin biopsies as predictors of these neurologic diseases.  If the technique proves useful, it may be possible to diagnose these disorders earlier and deploy proactive therapy…Some day soon.

https://jamanetwork.com/journals/jama/fullarticle/2816441

#skin #biopsy #parkinsons #dementia #psynuclein 

Vidcast:  https://www.instagram.com/p/C5WshKLr39o/

Columbia University biomedical engineers have harnessed the method by which cells normally communicate with each other in order to deliver poison pill chemotherapy directly to lung cancer cells.  Knowing that structures called exosomes are cell-to-cell messengers, the researchers have engineered these so-called extracellular vehicles to convey messengerRNA capable of directing lung cancer cells to produce suicidal chemotherapy.

Comparing their engineered exosomes to liposomes of the type successfully used to convey CoVid vaccine mRNA, they demonstrated the superiority of exosomes for chemotherapy delivery.  These exosomes, delivered by the latest inhalation devices, can transmit to ailing cells powerful immunotherapy including that driven by interleukins such as IL-12.

These bioengineered exosomes or EVs for extracellular vesicles can also be employed to deliver other agents to a variety of cells in a variety of diseased organs.  Though not yet being tested in clinical trials, we hope that these microscopic sacs of therapy will begin to save human lives…..someday soon.

https://tinyurl.com/bdyeamht

#exosomes #cancer #chemotherapy #immunotherapy #il12

Vidcast:  https://www.instagram.com/p/C5WrzUdr3Tr/

Those who religions’ dietary laws forbid the ingestion of any foods or proteins from pigs often use this prohibition as the reason for rejecting the use of vaccines including the measles vaccine for their children and themselves.  It is true that many vaccines do use porcine gelatin, but there is an alternative.

The Priorix Measles, Mumps, and Rubella vaccine contains beef rather than pig gelatin.  Studies have shown that Priorix is as effective and safe a vaccine as those that contain pig gelatin.

So…. If you adhere to kosher or Halal food laws, ask your child’s or your own medical team about Priorix.  You can protect your family and your community by preventing the spread of communicable disease and still be faithful to your religious beliefs.

https://www.cdc.gov/vaccines/acip/recs/grade/mmr-PRIORIX-etr.html

#mmr #vaccine #measles #pork #beef #gelatin #halal #kosher #muslim #judaism

Vidcast:  https://www.instagram.com/p/C5WrBg0rMGD/

Just as second hand smoke contains dangerous compounds that can induce lung disease and worse, the fumes from e-cigarettes are transmitting chemicals into the bodies of anyone in the vaper’s vicinity.  Nurse researchers from Emory University now report that metabolites of agents contained in vaping liquids have been detected in the blood and saliva of children whose parents use e-cigarettes.

Worse still, half of parents were unaware that e-cigarette vapors posed any risk to children.  Specifically, 58% of vaping parents in a focus group thought that vapors from their own devices were creating very mild or no risk to their own children.

The vapors from e-cigarettes contain addicting levels of nicotine as well as volatile organic compounds that have inflammatory and/or carcinogenic effects on the lungs.  If you must vape or smoke electronic cigarettes, don’t do it around your children or around any children.

https://www.clinicaladvisor.com/reports/secondhand-vaping-poses-hazards-children/

#vaping #ecigarettes #children #lungs #inflammation #carcinogens

Vidcast:  https://www.instagram.com/p/C5WpotMrR0E/

Ninety-five percent of benzoyl peroxide-containing cosmetics contain detectable levels of the human carcinogen benzene.  Even more worrisome: 89% of these products will harbor significantly toxic benzene concentrations if heated to levels considered safe by pharmaceutical standards.

These findings prompted the independent testing lab Valisure to seek a mandatory FDA recall of all acne medications that contain benzoyl peroxide or BP for short.  The tested products include Equate Beauty 2.5% BP cleansers, Neutrogena 10% BP cleanser, CVS Health 10% BP face wash, Walgreens 10% BP cream, Clean & Clear 10% cleanser, Equate Beauty 10% BP acne wash, and Proactiv 2.5% BP cleanser.

Predictably, some of the companies manufacturing BP-containing products as well their national trade association took issue with some of the test procedures.  Others groups have validated the reliability of these tests.

While more investigations are ongoing, the best advice is to avoid storing any of these BP-containing products at temperatures above room temperature.  If you live in a hot climate, refrigerate these products.  Furthermore, don’t use the products beyond their expiration dates.

This is an ongoing story, so stay tuned,

https://www.mdedge.com/dermatology/article/268410/acne/benzene-detected-benzoyl-peroxide-products-debate-implications?ecd=WNL_EVE_240325_mdedge

#benzoylperoxide #BP #benzene #carcinogen #heat #acne