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L-norvaline is a common amino acid component of popular body building supplements, but an Australian study just published by the journal Toxicology In Vitro shows that this compound can actually damage and kill human brain cells.
L-norvaline is touted as “one of the leading methods to safely and naturally boost nitric oxide levels to new heights.” High nitric oxide levels are said to accelerate blood flow, oxygen delivery, and muscle action. It is the chief ingredient in popular body-building supplements including Myonox, Charge, Pump Extrem, and Preseries Bulk.
The tissue culture studies show that l-norvaline initially permits brain cells to produce more energy, but, with continued exposure to this amino acid, the cell machinery employed to produce this energy is damaged. This is the cellular equivalent to revving your car engine too high for a prolonged period of time.
L-norvaline is a so-called non-protein amino acid because it is normally not used to make human proteins. There’s a reason for that. In nature, some non-protein amino acids are used by plants to kill other plants and eliminate competition for soil nutrients. L-norvaline itself is known to be toxic to bacteria and to some plants.
Food supplements are unregulated, and many of them have not undergone rigorous safety testing. If you want to build up your body, it is always safest to consume protein sources such as fish, poultry, fruits, and vegetables that have been time-tested safe and nutritous. Metabolic shortcuts are usually re recipes for disaster.
#body-building #norvaline #musclebuilding #nitricoxide #healthnews
Kate Samardzic, Kenneth J. Rodgers. Cytotoxicity and mitochondrial dysfunction caused by the dietary supplement l-norvaline. Toxicology in Vitro, 2019; 56: 163 DOI: 10.1016/j.tiv.2019.01.020
https://www.esupplements.com/best-l-norvaline-supplements/