Dr. Paika Podcast

#Peptides #GLP1 #WeightLoss #ObesityMedicine #longevity 

Peptides are everywhere online right now, but most videos explain one compound in isolation and skip the actual evidence. In this video, I break down every major peptide people are talking about — repair peptides, growth hormone secretagogues, longevity and immune peptides, hormonal peptides, and the GLP-1 family — with the real human trial data, FDA regulatory status, and honest caveats behind each one. No hype, no fear-mongering — just what the research actually supports.

I'm Dr. Mohammed Paika, a hospitalist physician. I see the downstream effects of unmanaged metabolic and hormonal health every day at the bedside, and this video is the same evidence-based breakdown I'd give a patient.

What's covered:
Repair — BPC-157, TB-500
Growth hormone axis — CJC-1295, Sermorelin, Tesamorelin, Ipamorelin, IGF-1 LR3, Follistatin-344
Aesthetic, immune & longevity — GHK-Cu, Epitalon, Thymosin Alpha-1, MOTS-c
Hormonal & quality of life — PT-141, DSIP
Metabolic & GLP-1 — AOD-9604, Semaglutide, Tirzepatide, Retatrutide, Cagrilintide

Timestamps
0:00 Intro
1:52 Regulatory Reality Check
4:03 Repair Peptides (BPC-157, TB-500)
9:23 Free Resources
10:14 Growth Hormone Axis Peptides
20:43 What's Coming Next
22:13 Aesthetic, Immune & Longevity Peptides
29:49 Hormonal & Quality-of-Life Peptides
32:47 Metabolic & GLP-1 Peptides
42:47 Closing & Next Steps

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

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🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine

Some foods, drinks, medications, and supplements can make Ozempic or Mounjaro harder to tolerate — and a few may raise your risk of more serious side effects. If you're dealing with nausea, reflux, constipation, dehydration, or stomach pain, something else in your routine might be making it worse.

In this video, board-certified Internal Medicine and Obesity Medicine physician Dr. Mohammed Paika breaks down 12 things to be careful with on Ozempic or Mounjaro — and exactly what to do instead. Drawing on 15+ years as a hospitalist and his own experience with GLP-1 therapy, Dr. Paika walks through the real mechanism behind each risk, the clinical reasoning, and simple fixes you can use starting today.

By the end, you'll know what may worsen side effects, what combinations need extra caution, and how to make your GLP-1 treatment safer and easier to stick with.

GO DEEPER: 🎓 GLP-1 Masterclass Course — the full physician-built framework for eating, training, and preserving muscle on a GLP-1: https://drmohammedpaika.com 📖 GLP-1 Masterclass Ebook — the same clinical framework, in book form 🍽️ Free GLP-1 Diet Cookbook — join the newsletter at https://drmohammedpaika.com and get it free 📕 The Physician's Physique — Dr. Paika's personal transformation story 📘 The Weight Equation — the deeper clinical science of obesity as a disease 🤝 Metabolic Health Community on Skool — ongoing support and direct access to Dr. Paika

TIMESTAMPS: 
0:00 – Intro: What This Video Covers 
0:54 – Meet Dr. Paika: Why Trust This List 
2:48 – #1 Oral Contraceptives 
4:16 – #2 Fried & Heavily Breaded Foods 
5:55 – #3 Carbonated & Sugary Drinks 
7:19 – #4 NSAIDs (Ibuprofen & Naproxen) 
8:52 – #5 Oversized Meals 
10:21 – #6 Spicy Foods 
11:45 – A Quick Word: The GLP-1 Masterclass 
12:29 – #7 Alcohol 
14:23 – #8 Insulin & Sulfonylureas 
15:56 – #9 Fiber & Bulk-Forming Supplements 
17:30 – #10 Levothyroxine & Timed Medications 
18:54 – #11 Opioids & Sedatives 
20:37 – #12 Warfarin 
22:06 – The Thyroid Cancer Myth, Explained 
23:35 – Final Takeaway 
24:24 – How to Go Deeper (Course, Books, Community)

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

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💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#GLP1 #WeightLossJourney #Zepbound #ObesityMedicine #Tirzepatide

You can be taking Zepbound exactly as prescribed and still be making mistakes that quietly stall your results. In this video, I break down the 6 most common mistakes I see — as a board-certified internal medicine and obesity medicine physician — that undermine fat loss, muscle preservation, and long-term success on Zepbound, plus two bonus insights most people never hear from their prescriber.

These aren't theoretical. They're pulled from my own clinical practice, my patients, and my own two personal body transformations.

Want the complete system — deficit strategy, protein targets, training plan, and exit strategy — built by a physician who's lived it? Visit drmohammedpaika.com to enroll in the GLP-1 Masterclass.

This video is for educational purposes only and is not a substitute for individualized medical advice from your own physician.

Timestamps

0:00 Intro — Why Zepbound Isn't Working the Way You Expected
0:51 Who I Am (And Why This Isn't Just Theory)
1:53 Mistake #1: Staying In a Deficit Too Long
6:22 Mistake #2: Not Drinking Enough Water
9:56 Mistake #3: Not Getting Enough Protein
15:32 Mistake #4: Letting the Medication Do All the Work
20:32 Mistake #5: Obsessing Over the Scale
25:07 Mistake #6: Skipping Strength Training
29:54 Bonus: Sleep, Stress & Cortisol
31:22 Bonus: Advocating For Your Own Pace
32:23 Final Takeaways + Next Steps

📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our complete resource library, including the GLP-1 Masterclass eBook and our books *The Physician's Physique* and *The Weight Equation*:
https://www.drmohammedpaika.com/newsletter

📘 GLP-1 Masterclass Book (PDF):
https://www.drmohammedpaika.com/glp1ebook

🎓 Complete GLP-1 Weight Loss Masterclass:
https://www.drmohammedpaika.com

👥 Join the Metabolic Health Community on Skool for live Q&As, evidence-based education, accountability, expert support, and a community of people committed to improving their metabolic health:
https://www.skool.com/metabolic-health-community-5316

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#Metabolism #FatLoss #GLP1 #WeightLossJourney #obesitymedicine 

Think a stalled scale means your metabolism has failed you? It probably hasn't — you're just watching the wrong number. In this video, hospitalist physician and exercise scientist Dr. Mohammed Paika breaks down the 5 real, medically-backed signs your metabolism is actually burning fat, why "fast metabolism" is often a myth, and where a lot of popular advice gets the science dangerously wrong (including the real difference between nutritional ketosis and diabetic ketoacidosis).

Go deeper at drmohammedpaika.com:
→ GLP-1 Masterclass (course + e-book) — the full science of satiety and appetite regulation
→ Free GLP-1 Diet Cookbook — sign up for the newsletter
→ The Weight Equation — the complete science of obesity medicine
→ The Physician's Physique — Dr. Paika's personal story

TIMESTAMPS
0:00 – The Problem With the Scale
1:04 – Why Listen to Me: Hospitalist 
2:38 – Weight Loss Is Not Fat Loss
3:45 – Sign 1: Your Body Fat % Is Dropping
6:54 – Sign 2: Steady Energy & Mental Clarity
10:03 – Sign 3: Your Sugar Cravings Have Quieted Down
13:41 – Sign 4: Satisfied After Meals, Longer Between Them
17:10 – Sign 5: You're Sleeping Deeply
19:12 – Recap + Free Resources

📩 Subscribe to our newsletter for weekly insights on GLP-1 science, metabolic health, longevity, and healthy recipes — plus a free GLP-1 Diet Cookbook when you subscribe: https://www.drmohammedpaika.com/newsletter
📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook
🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#Ozempic #GLP1 #Semaglutide #WeightLossJourney #ObesityMedicine

Most Ozempic and Mounjaro side effects are just uncomfortable — but a few can land you in the ER. In this video, Dr. Mohammed Paika (board-certified internal medicine + obesity medicine physician, 15+ years as a hospitalist) breaks down which GLP-1 side effects are genuinely dangerous, who's at higher risk, and the exact red-flag symptoms you should never wait out.

What's covered:

Why GLP-1 side effects happen (the mechanism in plain terms)
Nausea/vomiting: normal vs. red flag
Dehydration and acute kidney injury
DKA risk for diabetics on GLP-1s
Gallbladder disease and pancreatitis
Gastroparesis, explained without the internet hype
The thyroid cancer warning — what the label actually means
Muscle loss: the side effect no one talks about (and how to prevent it)
Mood changes and when to get help
A full red-flag quick-reference recap

This video is for education, not medical advice — always talk to your own prescriber about your specific situation.

Want the full system for nutrition, protein targets, training, and side-effect management on GLP-1 medications? Join the GLP-1 Masterclass at https://drmohammedpaika.com

If this helped, subscribe for the next video on structuring protein and training week-by-week on these medications.

If you or someone you know is struggling with thoughts of self-harm, call or text 988 (Suicide & Crisis Lifeline).

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

Timestamps
0:00 Intro
0:49 Who I Am
2:58 Why GLP-1 Side Effects Happen
3:57 Nausea & Vomiting: Where It Usually Starts
5:05 Dehydration & Acute Kidney Injury
7:41 Starvation Ketosis & DKA Risk
9:37 Quick Note: GLP-1 Masterclass
10:17 Gallbladder Disease & Pancreatitis
12:35 Gastroparesis: The Internet-Famous One
14:01 The Thyroid Cancer Myth
15:55 Muscle Wasting: The One I See Most Often
19:13 Mood Changes & Depression
21:01 Who Is At Higher Risk: The Summary
21:59 The Red Flags: Quick Recap
22:43 Close & Next Steps

References:
FDA Prescribing Information — Ozempic (semaglutide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/209637s020s021lbl.pdf)

FDA Prescribing Information — Mounjaro (tirzepatide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215866s039lbl.pdf)

FDA Prescribing Information — Zepbound (tirzepatide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/217806s042lbl.pdf)
(Wegovy shares the same active ingredient, semaglutide, and labeling basis as Ozempic.)

Wilding JPH, et al. STEP 1 body composition sub-study — DEXA data on fat vs. lean mass loss: [J Endocr Soc](https://academic.oup.com/jes/article/5/Supplement_1/A16/6240360)

Look M, et al. SURMOUNT-1 body composition sub-study — lean mass findings on tirzepatide: [Diabetes Obes Metab, 2025](https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.16275)

Bjerre Knudsen L, et al. Endocrinology 2010;151(4):1473-1486 — the rodent thyroid C-cell study behind the boxed warning: [Oxford Academic](https://academic.oup.com/endo/article/151/4/1473/2456651)

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#Longevity #AntiAging #GLP1 #MetabolicHealth #Biohacking

You don't need a complicated longevity routine to start aging better — you need to know which habits actually move the needle. In this video, hospitalist and obesity medicine physician Dr. Mohammed Paika breaks down the evidence-based habits, blood work targets, and training principles that drive real energy, better labs, and a longer, stronger life.

In this video, you'll learn:
- The four free daily habits — grounding, breathwork, morning sunlight, and cold exposure — and the research behind each one
- The truth about cholesterol, triglycerides, and statins (and why one number on your lab report isn't the whole story)
- Why food quality matters more than which diet you follow, including an honest look at seed oils and GMOs
- Why muscle is your most powerful longevity organ, and the two benchmarks proven to predict how long you'll live
- The exact annual blood panel to ask your doctor for
- How all of this connects to metabolic health and GLP-1 medications

📩 Subscribe to our newsletter for weekly insights on GLP-1 science, metabolic health, longevity, and healthy recipes — plus a free GLP-1 Diet Cookbook when you subscribe: https://www.drmohammedpaika.com/newsletter
📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook
🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com

Timestamps
0:00 Intro — Why Habits Matter More Than Trends
0:58 Why I'm Qualified to Tell You This
2:12 Aging Is a Life Engineered for Comfort
4:20 Habit 1 — Grounding
6:22 Habit 2 — Breathwork
8:54 Free Newsletter + GLP-1 Cookbook
9:39 Habit 3 — Sunlight & Vitamin D
12:01 Habit 4 — Cold Exposure & Hormesis
14:34 The Truth About Cholesterol, Triglycerides & Statins
19:45 Food Quality — Seed Oils, GMOs & B12
24:10 Muscle — Your Most Powerful Longevity Organ
28:32 The Annual Blood Work You Need
30:57 How This Connects to GLP-1s & Weight Loss
32:22 Your Daily & Weekly Protocol
33:32 What to Do Next

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

References
1. NHLBI ATP III — nhlbi.nih.gov/files/docs/guidelines/atp3xsum.pdf
2. Harvard Health — health.harvard.edu/heart-health/how-its-made-cholesterol-production-in-your-body
3. Krauss, Circulation — ahajournals.org/doi/10.1161/01.cir.0000033222.75187.b9
4. Insulin/Lipolysis — pmc.ncbi.nlm.nih.gov/articles/PMC7227813
5. NTP Fluoride 2024 — ntp.niehs.nih.gov/publications/monographs/mgraph08
6. FWW v. EPA — foodandwaterwatch.org/2024/09/25/historic-court-decision-in-fluoridation-toxicity-case-orders-epa-to-act
7. Natl. Academies GMO — nap.nationalacademies.org/read/23395
8. Leong, Lancet 2015 — thelancet.com/journals/lancet/article/PIIS0140-6736(14)62000-6/abstract
9. Momma, BJSM 2022 — pubmed.ncbi.nlm.nih.gov/35228201
10. Kox, PNAS 2014 — pnas.org/doi/10.1073/pnas.1322174111
11. van Marken Lichtenbelt, NEJM — nejm.org/doi/full/10.1056/NEJMoa0808718
12. Sacks, Circulation 2017 — ahajournals.org/doi/pdf/10.1161/cir.0000000000000510
13. NIH ODS Vitamin D — ods.od.nih.gov/factsheets/VitaminD-HealthProfessional
14. StatPearls Testosterone — ncbi.nlm.nih.gov/books/NBK526128
15. Cleveland Clinic Sarcopenia — my.clevelandclinic.org/health/diseases/23167-sarcopenia
16. Attia, Outlive — peterattiamd.com/outlive
17. Marchand Case Study — foreverfitscience.com/research/breaking-records-and-barriers-robert-marchand
18. Chevalier 2012 — pmc.ncbi.nlm.nih.gov/articles/PMC3265077
19. Simmons Podcast — theringer.com/2016/06/08/nba/nba-lebron-james-bill-simmons-malcolm-gladwell-5369d6959c67

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#GLP1 #Ozempic #Zepbound #WeightLossJourney #ObesityMedicine

Injecting your GLP-1 in the same spot every week and wondering if another site would work better? I break down the actual Eli Lilly pharmacokinetic study comparing abdomen, thigh, and upper arm injections for tirzepatide (Mounjaro/Zepbound) — what the data really shows about absorption, side effects, and appetite suppression, and where the study's small sample size means the "abdomen wins" headline deserves a second look.
By the end, you'll know exactly how much injection site affects your results — and where to actually focus if you want long-term success on GLP-1 therapy.
Learn the full framework I use with my own patients — nutrition, training, and troubleshooting your treatment — inside my GLP-1 Masterclass: https://drmohammedpaika.com

Timestamps
0:00 Cold Open
0:57 Meet Dr. Paika
1:38 The 3 Questions This Video Answers
2:50 How GLP-1 & GIP Actually Work
4:57 The 3 FDA-Approved Injection Sites
6:18 Why This Study Matters
7:58 Inside the Study: Design & Methodology
9:06 The Half-Life Detour (Why 35 Days)
10:27 Finding #1: Total Drug Absorbed (AUC)
12:55 Finding #2: Peak Concentration (Cmax)
14:16 Finding #3: Side Effects & Appetite Suppression
15:50 Patient Story: 61 Lbs Down
17:20 Does Rotating Injection Sites Matter?
19:44 My Actual Recommendation
21:09 Where to Go From Here

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#CreatineAfter50 #GLP1 #HealthyAging #MuscleHealth #Sarcopenia

Is creatine actually worth it after 50 — or is it just hype? In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine) breaks down what 680+ clinical trials say about creatine for muscle, brain, and heart health after 50 — plus the one thing almost nobody tells you if you're losing weight quickly, especially on a GLP-1 medication like semaglutide or tirzepatide.

You'll learn: the real history of creatine, how it works in your cells, why muscle loss (sarcopenia) accelerates after 40, the safety facts worth knowing (including the kidney-lab myth), why losing weight fast can mean losing muscle, and simple, no-nonsense dosing.

If you're losing weight and want to make sure it's fat you're losing, not muscle, check out my GLP-1 Masterclass at drmohammedpaika.com — link below. This video is for general education only, not a substitute for personalized medical advice.

Timestamps
0:00 – Cold Open: Why Losing Weight Isn't the Same as Losing Muscle
1:20 – Meet Dr. Paika: My Story & Why This Matters
2:35 – The Real History of Creatine (Bill Phillips to 680+ Trials)
3:42 – What Creatine Actually Is (And Isn't)
4:39 – Sarcopenia: The Muscle-Loss Clock After 40
5:49 – The Catch: Creatine Isn't Magic
6:44 – Beyond Muscle: Brain, Heart & Mood Benefits
8:01 – Safety: What the Research (and My Hospital Floor) Show
10:19 – The Scale Lie: Water Weight vs. Fat
11:10 – Creatine + GLP-1: The Missing Piece
12:58 – Who Should Actually Take Creatine
13:36 – Dosing Made Simple (No Overcomplicating)
14:50 – Key Takeaways & the Final Verdict
15:58 – Closing Thoughts & What to Watch Next

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

References:
1. ISSN Position Stand on Creatine Safety & Efficacy (2017): https://pmc.ncbi.nlm.nih.gov/articles/PMC5469049/
2. Creatine + Resistance Training in Older Adults, meta-analysis: https://pubmed.ncbi.nlm.nih.gov/24576864/
3. Creatine and Kidney Function, meta-analysis (2025): https://link.springer.com/article/10.1186/s12882-025-04558-6
4. Creatine-Induced Kidney Failure narrative review: https://pmc.ncbi.nlm.nih.gov/articles/PMC10054094/
5. Creatine in Heart Failure, systematic review (2025): https://www.heartlungcirc.org/article/S1443-9506(25)00791-7/fulltext
6. Creatine and Cognitive Function, meta-analysis: https://pmc.ncbi.nlm.nih.gov/articles/PMC11275561/
7. Lean Mass Preservation in GLP-1 Treatment, review: https://www.mdpi.com/2218-1989/16/6/364
8. SEMALEAN Study (semaglutide, fat/lean mass): https://pmc.ncbi.nlm.nih.gov/articles/PMC12673431/

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⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#Retatrutide #GLP1 #WeightLossScience #ObesityMedicine #GLP1Masterclass

Is retatrutide the real deal, or just another overhyped GLP-1 headline? In this video, Dr. Mohammed Paika — board-certified in Internal Medicine and Obesity Medicine — breaks down exactly how retatrutide's triple-hormone mechanism (GLP-1 + GIP + glucagon) works, what the Phase 2 trial data actually shows, and where the online hype outruns the evidence.

You'll learn why weight loss and fat loss aren't the same thing, why muscle loss is the most overlooked risk on any GLP-1 medication (and exactly how to prevent it), what's really happening in your brain on these drugs, and the honest side-effect and safety picture — including the boxed warning most videos skip.

Retatrutide is still investigational and has not been FDA-approved. This video is for education only and is not medical advice — always talk to your own physician before starting or changing any treatment.

Want the complete framework for using GLP-1 therapy correctly — protein targets, a 12-week body recomposition program, and real answers to the questions patients ask every day in clinic? Check out the GLP-1 Masterclass at https://drmohammedpaika.com

Timestamps
0:00 – Cold Open: Is Retatrutide Actually Different?
1:01 – The Disclaimer
1:50 – Meet Retatrutide: The Triple Agonist
2:42 – Lever One: GLP-1
3:48 – Lever Two: GIP
4:49 – Lever Three: Glucagon
7:10 – Three Levers, One Machine
7:49 – Quick Recap
8:33 – Why Your Body Actually Stores Fat
10:36 – Why the Scale Lies to You
12:16 – The Brain Connection
13:57 – The Part Everyone Gets Wrong: Muscle
17:45 – What the Trials Actually Show
19:26 – Side Effects & Who Should Be Cautious
21:02 – Is the Hype Ahead of the Evidence?
22:21 – What I Tell My Own Patients to Do
24:02 – Closing: The GLP-1 Masterclass

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
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🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

#Ozempic #GLP1WeightLoss #ObesityMedicine #MuscleSparingWeightLoss #WegovyTips

Taking Ozempic, Wegovy, Zepbound, or Mounjaro exactly as prescribed — but the scale has stalled? In this video, board-certified physician Dr. Mohammed Paika breaks down the 3 foods most likely to be quietly working against your GLP-1 medication, the exact physiology behind why each one stalls fat loss and drains muscle, and what to eat instead to keep losing fat while protecting your muscle and metabolism.
Dr. Paika is a board-certified Internal Medicine and Obesity Medicine physician, and a certified personal trainer and nutrition coach — bringing both the medical and the practical fitness/nutrition side of GLP-1 therapy into one place.

Timestamps
0:00 – Why the medication usually isn't the problem
0:55 – The physiology: how GLP-1 medications actually work
2:05 – Food #1: Fried & heavy, greasy foods
5:40 – Food #2: Sugary drinks, refined carbs & pastries
8:50 – Food #3: Alcohol — the one nobody talks about
12:05 – Why this isn't just theory (the pattern I see in practice)
14:10 – The real principle: fat loss with muscle preservation
16:00 – Quick recap: all 3 foods and the fix
16:50 – What to do next (Masterclass + book)

GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com
Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ 
Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4

👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA
Board-Certified in Internal Medicine and Obesity Medicine
Certified Personal Trainer & Nutrition Coach
Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine.

👍 Like
💬 Comment
📌 Share
🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions

⚕️ MEDICAL & EDUCATIONAL DISCLAIMER
This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional.
Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.
Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications.
Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes.
Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.