The role of thrombolysis in submassive PE remains controversial to date. In this podcast, Dr Chacko & I dive deeper to explore the current evidence on this topic.

Liberating high-risk patients from mechanical ventilation poses a unique challenge to all intensive care physicians. The use of high flow has increased over the last decade, however, combination of high flow nasal oxygen and NIV has not been tested so far. The present study published in JAMA tries to answer this dilemma.

The use of IV albumin is not uncommon in the Intensive care unit. However, the evidence for its routine use is conflicting. In this podcast, Dr Chacko and I critically appraise the available evidence to inform the Intensive care community on the role of IV albumin in the intensive care unit.

Status epilepticus poses a significant challenge to intensive care physicians. There is lots of uncertainty about the treatment options and correct dosing. In this podcast, we discuss the landmark ESETT trial published in NEJM which explores this dilemma but rather helping to solve the problem, asks more questions.

Intracranial pressure monitoring is an integral part of Traumatic brain injury(TBI) management in intensive care. In this podcast, we critically appraise the evidence available on this topic to inform ICU clinicians about the current trends.

The role of prophylactic antibiotics in post-cardiac arrest survivors who undergo therapeutic hypothermia management is controversial. This recently published trial raises the question of current clinical practices and forces us to rethink our strategies.

Stress ulcer prophylaxis is routinely used in intensive care. The evidence available is quite conflicting and practices still vary across the globe. In this podcast, we dive deeper into the available evidence to discuss the pros and cons of using SUP in ICU.

Oxygen is a drug and needs to be used cautiously. In this podcast, Dr Chacko & I critically appraise the landmark trial ICU -ROX from ANZICS CTG. 

RBC transfusions remain an important treatment for improving tissue oxygenation in the setting of inadequate oxygen-carrying capacity. However, the management of anemia and its impact on critically ill patients has been a matter of debate. In this podcast, Dr. Chacko & I discuss the evidence behind different transfusion thresholds used in critically ill patients.

This podcast is dedicated to all female researchers in Medicine and in particular to Dr Utako Okomoto. CRASH 3 trial is a victory not only for tranexamic acid but also for Utako and her husband's struggle. In this podcast, Dr Chcko & I discuss practice-changing CRASH 3 trial in-depth.