In this episode we explore the bi-directional relationship between food allergies and eczema with two leading pediatric allergists.  Our guests are Dr. Anne Marie Singh, an allergy and immunology specialist with a focus in pediatrics with the University of Wisconsin School of Medicine and Public Health, and Dr. Peck Ong, Associate Professor of Clinical Pediatrics at the University of Southern California and attending physician in the Division of Clinical Immunology and Allergy at Children’s Hospital in Los Angeles. Our conversation explores how and when food allergies can trigger eczema as well as how eczema can serve as the gateway to food allergies; new approaches to treating food allergy; and future directions for preventing both conditions.

 Research referenced in this episode: 

Controversies in allergy: food testing and dietary avoidance in atopic dermatitis

Scratching the skin primes the gut for allergic reactions to food

This podcast episode was produced in collaboration with the Revolutionizing Atopic Dermatitis Conference with support from Sanofi Genzyme and Regeneron.

How close are we to targeted treatments designed to each person with eczema? As parents, we often hear from people about a miracle approach that “cured” their or their child’s eczema, only to find that this same approach doesn’t work for us. We are continually reminded of the many different ways that eczema can appear and feel, and how people respond differently to different treatments. Right now, we have a largely “trial and error” approach to treating eczema but what will the future look like as we begin to understand eczema variation, subtypes, and personalized medicine? In this episode of the Eczema Breakthroughs podcast we chat with Professor Thomas Bieber who is chair and director of the department of dermatology and allergy at the University of Bonn in Germany. His cutting edge research focuses on biomarker discovery and precision medicine in allergic skin diseases, and he was a speaker on the topic of risk stratification at the recent Revolutionizing Atopic Dermatitis global conference in April.  

Research referenced in this episode:

Eczema types: Where are we and where should we go?

In this episode six parents of children with eczema from around the world share common experiences, challenges and silver linings from their eczema journeys, and dispel myths and misperceptions about the condition. Join us for this special edition of Eczema Breakthroughs recorded for World Atopic Eczema Day (#atopiceczemaday), which takes place annually on September 14th. Episode 7 is co-hosted with Keri Kelley.

What do the Iditarod and the immune system have in common? How can we harness the body’s defenses for fighting off infections and invaders to tackle eczema and its complications, including eczema herpeticum.  Our guest for this episode of Eczema Breakthroughs is Dr. Brian Kim, Assistant Professor of Dermatology, Anesthesiology, Pathology and Immunology, and Co-Director of the Center for the Study of Itch at Washington University School of Medicine in St. Louis. His laboratory focuses on the immune mechanisms that underlie skin inflammation and the sensation of itch, and his groundbreaking translational research is showing new ways for addressing eczema by priming – rather than discouraging – the immune system. 

Research referenced in this episode: Revving up the immune system may help treat eczema

There’s a battle underway on the skin between bacteria that make eczema worse and bacteria that can improve eczema symptoms. This fascinating discussion with Dr. Richard Gallo, Chairman of the Department of Dermatology at the University of California-San Diego, explains his ground-breaking research approach which amplifies the presence of “good” bacteria in order to control overgrowth of problematic strains, like Staph aureus, and ultimately help people with eczema.

This podcast was recorded in 2018 as part of GPER’s research meetup series.

Research referenced in this podcast:

Eczema-associated bacteria may be kept in check by a different microbe

The microbiome in patients with atopic dermatitis

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

Almost every week we hear about new treatments for eczema, many with names that are hard to pronounce and even harder to remember. After a long drought, we’re suddenly experiencing a downpour in new options, but for parents and patients, it’s hard to navigate this evolving landscape. Dr. Eric Simpson, a dermatologist with OHSU and leading expert on new eczema treatments, walks us through what’s new, what’s coming, and how to make sense of it all. 

Research referenced in this podcast:

Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis

Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis

Therapeutic Pipeline for Atopic Dermatitis: End of the Drought?

This podcast was co-hosted by the Pediatric Dermatology Research Alliance (PeDRA), and produced in collaboration with the Revolutionizing Atopic Dermatitis Conferencewith support from Sanofi Genzyme and Regeneron.

Oral and systemic steroids are used to treat eczema all the time, but are they safe and do they make sense for a long-term chronic disease? Antihistamines are the most commonly prescribed oral treatment for eczema, but do they actually address its symptoms? Dr. Jonathan Silverberg, a dermatologist and researcher with George Washington University, offers some straight talk in this episode of Eczema Breakthroughs. Tune in!

Research referenced in this podcast:

Comorbidities and the impact of atopic dermatitis

Use of systemic corticosteroids for atopic dermatitis

Increased ADHD symptoms in atopic dermatitis are associated with antihistamine use

A systemic review of the safety and efficacy of systemic steroids

This podcast was produced in collaboration with the Revolutionizing Atopic Dermatitis (RAD) Conference and with support from Sanofi Genzyme and Regeneron.

Why is eczema prevalence on the rise? Are chemicals found in many skin and cosmetic products partially to blame? How do we restore a healthy balance of bacteria on eczema-prone skin? Is the idea that eczema is a “genetic” disease a myth? Learn more in this provocative chat with Dr. Ian Myles, a cutting-edge researcher with the NIH who studies “microbiome transplants” for the treatment of eczema.

This episode was recorded, June 14th, 2019 as part of GPER’s Research Meetup series.

Research referenced in the podcast:

·     First-in-human Topical Microbiome Transplantation with Roseomonas Mucosa Bacteria

·     Allergy of Disease of Dysbiosis

Can you control itch with acupressure? Do toxins from bacteria drive eczema symptoms? What is the Dr. Aron Regimen and does it work? How should we think about long-term steroid use? Learn more in this interview with a Dr. Peter Lio, Assistant Professor of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine, Founding Director of the Chicago Integrative Eczema Center, and a true pioneer in eczema treatment and research.

This episode was recorded August 16, 2016 as part of GPER’s Research Meetup series.

Research referenced in the podcast:

·     Acupressure study

·     Review of alternative and complementary treatments for eczema

·     Case series study on CASM (or Aron Regimen)

·     Review of the relationship between staph and eczema