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Despite decades of progress, elevated low-density lipoprotein cholesterol remains one of the most important modifiable risk factors for cardiovascular disease. In this episode, Kausik Ray explores the evidence linking low-density lipoprotein cholesterol to atherosclerosis, discusses the challenges of achieving lipid targets in clinical practice, and reviews the latest therapeutic advances, from statins and ezetimibe to proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and emerging treatments.
Timestamps:
00:00 – 01:17: Intro
01:17 – 02:23: LDL cholesterol
02:24 – 05:20: Management barriers
05:21 – 09:07: Treatment landscape
09:08 – 14:38: Familial hypercholesterolemia
14:39 – 18:42: Looking ahead
Join Kausik Ray for a rapid-fire introduction to the evolving world of cardiovascular prevention. In just a few minutes, discover why cardiovascular disease remains the leading cause of death globally, the key role of cholesterol and cardiometabolic risk factors, and the innovations that could reshape prevention in the years ahead. This episode provides a concise overview of the themes explored throughout the series.
In the final episode, Christopher Griffiths looks to the future of psoriasis research and care. From AI and global collaboration to improving access to advances in inflammatory skin disease, he explores the opportunities and challenges that could shape the next decade of psoriasis research.
Timestamps:
00:47 – Next decade of psoriasis research
03:33 – AI in psoriasis care
04:36 – Global collaboration
06:22 – Ensuring global access
How has psoriasis treatment changed beyond recognition? In Part 2, Christopher Griffiths discusses advances in treatment, precision medicine, and biomarkers, alongside insights from PSORT and BADBIR. He explores how real-world evidence complements clinical trials and how treatment success has evolved to focus on improving patients' lives.
Timestamps:
00:46 – Changing treatment landscape
02:05 – Precision medicine in psoriasis
03:19 – Promising biomarkers
07:16 – BADBIR
09:09 – Clinician and patient relationship
10:02 – Definition of treatment success
Christopher Griffiths joins host Saranya Ravindran to explore how our understanding of psoriasis has evolved from a disorder of skin cell proliferation to a complex immune-mediated inflammatory disease. Discover the breakthroughs that transformed psoriasis research and why the condition has become a model for understanding inflammation.
Timestamps:
00:56 – Previous understanding of psoriasis
01:57 – Psoriasis as an immune-mediated disease
03:30 – Psoriasis as a model disease
04:14 – International Psoriasis Council
05:41 – Unanswered questions in psoriasis
In this rapid-fire episode, Christopher Griffiths answers key questions about psoriasis, from what first drew him to the disease and the biggest changes in our understanding to the scientific breakthroughs transforming patient care. He also considers whether psoriasis could one day be prevented and what unanswered questions remain.
In the final episode of the series, Monica McLemore discusses nursing leadership, research translation, community partnership, and the future of reproductive healthcare. Drawing on her experience across clinical nursing, public health, academia, and policy, she explores how evidence can influence practice, why accessible science communication matters, and how nurses can help advance reproductive justice.
Timestamps:
48:52 – Shaping reproductive healthcare across settings
52:16 – Translating research into practice and policy
57:44 – Making health equity research accessible
61:02 – Nursing's role in advancing reproductive justice
64:51 – The future of reproductive and maternal healthcare
Monica McLemore joins host Catherine Glass to explore the persistent racial inequities affecting maternal health. From structural racism and barriers within healthcare systems to racism experienced in neonatal intensive care, this episode examines why disparities persist and how clinicians, researchers, and communities can work together to create meaningful change.
Timestamps:
05:02 – Drivers of racial inequities in maternal health
07:58 – Structural barriers to equitable pregnancy care
12:38 – Racism in neonatal intensive care
16:15 – Becoming an agent for healthcare change
21:25 – Moving beyond disparity documentation
25:51 – The role of community-engaged research
32:28 – Progress and challenges in maternal health equity
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