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In this special countdown episode, the EMJ Podcast team looks back at the 10 highest-performing episodes of 2025. Spanning neurology, cardiology, gastroenterology, women's health, respiratory medicine, and digital innovation, these conversations captured the topics that mattered most to clinicians worldwide. From chronic pain and anxiety to glucagon-like peptide-1 therapies, antimicrobial stewardship, and extended reality in medicine, this episode revisits the expert insights, emerging ideas, and clinical debates that shaped healthcare discussions throughout the year.
Timestamps:
00:00 – Introduction: the year in review 01:52 – Gravity and human health 06:28 – Antimicrobial stewardship in children 10:15 – Healthcare communication and leadership 13:04 – Rare lung diseases and early diagnosis 16:56 – Colonoscopy and cancer prevention 21:17 – Extended reality in clinical care 25:25 – Advances in heart failure research 34:07 – Obesity management in the GLP-1 era 20:35 – Women's health across borders 39:40 – The pain–anxiety connection
In this special two-part episode of Onc Now, Catherine Glass returns to take you through the incredible lineup of guests from 2025. From award winners to pioneering clinicians and researchers, this podcast has spotlighted some of the leading voices in oncology. Explore their most impactful insights and hear how recent advances are shaping clinical practice and future research.
Timestamps:
00:00 – Introduction
01:15 – Landscape of HER2 breast cancer
06:03 – Evolution of lung cancer research
09:10 – Breakthroughs in kidney cancer care
11:45 – A new era in liver cancer treatment
In this third and final deep-dive episode, Nicholas Simmonds highlights the importance of collaborative networks, such as the European Cystic Fibrosis Society (ECFS) Clinical Trials Network, in enabling global clinical trials. He also emphasises the central role of the patient voice in developing new therapies, using CFTR modulators as a key example.
Timestamps:
00:00 – Introduction
00:55 – ECFS Network
03:29 – Trial design
04:54 – Therapy frontiers
07:48 – Curative approaches
13:07 – Clinician message
How is cystic fibrosis diagnosis evolving? In this second deep dive, Nicholas Simmonds explores advances in diagnostic tools and shares his experience with the CF registry, highlighting its value as a powerful resource for tracking long-term treatment effectiveness. A must-listen for clinicians and anyone interested in how cystic fibrosis is diagnosed, and how progress is monitored over time.
Timestamps:
00:00 – Introduction
00:52 – Adulthood diagnosis
06:00 – Advanced diagnostics
10:37 – Survival variability
15:05 – CF Registry
Nicholas Simmonds joins host Saranya Ravindran for a deep dive into how adult cystic fibrosis (CF) care is evolving. Drawing on decades of experience, he discusses the major shifts in adult CF management, the vulnerable transition from paediatric to adult services, and strategies that ensure a smooth handover. Explore how longer survival brings new challenges, from fertility to mental health and emerging comorbidities, and why continuity of multidisciplinary care is more crucial than ever.
Timestamps:
00:00 – Introduction
01:15 – Adult care
04:12 – Smooth handover
10:10 – Evolving needs
In this rapid-fire episode, Nicholas Simmonds answers key questions about cystic fibrosis (CF), from common misconceptions and the value of registry data to CF testing, and the transition from paediatric to adult care. Perfect for listeners short on time.
In the final part of this deep dive series, David Heymann looks ahead to future threats, from antimicrobial resistance to zoonotic spillovers, and the innovations that offer hope. He discusses next-generation diagnostics and vaccines, the rise of the One Health approach, and the need for better global financing and communication strategies. The episode closes with guidance for future public health leaders.
Timestamps:
00:00 – Introduction
01:40 – Next pandemic
02:29 – Today's threats
04:27 – Diagnostic innovations
05:47 – Vaccine innovations
06:21 – One Health
08:20 – Funding
10:38 – Addressing misinformation
15:42 – Advice for the next generation
In Part 2 of this deep dive series, David Heymann examines how global surveillance systems operate, why international coordination remains difficult, and how eradication efforts, such as those for polio, continue to strengthen health infrastructures. He reflects on the realities of responding in low-resource settings and the tension between rapid emergency interventions and sustainable system-building.
Timestamps:
00:00 – Introduction
01:00 – Disease surveillance
02:44 – International coordination
04:39 – Polio eradication
06:20 – Low-resource settings
08:46 – Rapid response versus capacity building
10:04 – Lessons learnt
In this special two-part episode of Onc Now, Catherine Glass takes you through the incredible line-up of guests from 2025. From award winners to pioneering clinicians and researchers, this podcast has spotlighted some of the leading voices in the field of oncology. Explore their most impactful insights and hear how recent advances are shaping clinical practice and future research.
Timestamps:
00:00 – Introduction
1:17 – Importance of palliative care
5:55 – Obesity and carcinogenesis
9:28 – Colorectal cancer advances
12:06 – Navigating fertility preservation
15:06 – ESGO 2025 reflections
17:44 – The future of cancer vaccines
22:18 – Impact of diet on prostate cancer
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