EMJ Podcast: Insights For Healthcare Professionals

This week, Jonathan welcomes Mark Connors to explore the advancements in HIV vaccine technology and the progress in global understanding of HIV since the 1980s, highlighting how these insights can inform approaches to other viruses.

Use the following timestamps to navigate this episode:

(00:00)-Introduction

(01:28)-Mark's perfect menu

(03:23)-Choosing immunology and HIV research

(05:30)-HIV in the early 80s

(07:50)-T cell responses in controlling HIV

(13:45)- HIV history lesson

(20:50)-Merging our understanding of HIV with cancer immunotherapy

(23:12)-Challenges and breakthroughs in HIV vaccine development

(27:20)-T cell mechanisms at the sub-cellular level – the key to immunotherapies?

(29:25)-Immune responses to other viruses

(31:32)-Origin of HIV

(33:28)-Mark's three wishes for healthcare

In this episode of Hema Now, Jonathan Sackier welcomes Christopher Patriquin, a leading expert in the field of hematology and rare diseases. With a wealth of experience in teaching, consulting, clinical research, and hosting excellent dinner parties, Patriquin's discussion sheds light on many fascinating topics.

Timestamps:

(00:00)-Introduction

(02:00)-Dogs and dinner parties

(05:23)-Diagnosing and treating rare diseases

(09:42)-Cognitive decline in TTP survivors

(13:01)-Complement component 3 PNH therapy

(16:04)-Importance of apheresis medicine

(23:34)-The International PNH Registry

(26:52)-Developments in hematology

(28:56)-Equity and equality in access to care

(31:25)-Christopher's three wishes

This week, Jonathan is joined by David Resühr, to discuss advances in ultrasound imaging for anatomy education, and the innovative applications of 3D printing in medicine.

Timestamps:

(00:00)-Introduction (03:33)-Early life and career beginnings (05:58)-Ultrasound imaging for anatomy education (09:07)-3D printing in medicine (14:14)-Innovations on the horizon (20:00)-Mindfulness and preventing burnout (26:47)-Ultrasound phantoms (29:10)-Becoming an author (32:34)-Cadavers versus computers (38:25)-David's three wishes for healthcare

David Resühr's YouTube channel can be found here: https://www.youtube.com/@anatomyinsight

Sarah Blagden, pioneer in experimental oncology, returns to the podcast to discuss cancer prediction and prevention, and the future of cancer vaccines.

Timestamps:

(00:00)- Introduction

(00:35)- The mission of RNA Guardian Ltd

(02:02)- mTOR in cancer biology

(06:24)- Raising awareness of ovarian cancer

(08:32)- A new era of cancer prediction and prevention

(11:38)- The future of cancer vaccines

(15:58)- Advice to medical students: academia versus medicine

(19:42)- Sarah's three wishes for healthcare

This podcast was initiated and funded by Convatec. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Convatec or EMJ.

Supporting the role of nurses and multi-disciplinary teams in intermittent catheter care, providing insight into educational tools to support and improve patient wellbeing and advance the standard of care.

8 This week, Jonathan is joined by Chris McIntosh, to discuss the advancement of AI from "bench-to-bedside", while considering concerns around bias and fairness when working with diverse patient populations.

Use the following timesamps to navigate the episode:

(00:00)-Introduction

(02:28)-An early interest in computer science

(04:13)-Clinical collaborations

(07:46)-AI from "bench to bedside"

(10:08)-Transfer and meta-learning

(12:20)-Transparency in AI

(16:32)-Commercialising radiation therapy

(18:40)-AI revolutionising oncology

(20:49)-Treating cardiovascular disease

(25:45)-Bias in AI datasets

(31:47)-The future of AI

(35:00)-Chris' three wishes for healthcare

This week Jonathan is joined by Joshua Zeidner, Associate Professor of Medicine, University of North Carolina School of Medicine, USA. Together, they discuss findings from recent research and treatment options for acute myeloid leukaemia and myelodysplastic syndrome.

Timestamps:

(00:00)- Introduction

(01:57)- Joshua's love for the New York Giants

(04:28)- Treatment outcomes in IDH1 and IDH2-mutated acute myeloid leukaemia (AML)

(08:05)- Safety and efficacy of new agents in AML

(17:00)- Treatments for patients with AML with a TP53 mutation

(22:02)- Reliance on transfusion in myelodysplastic syndrome (MDS)

(25:44)- The time from research lab to bedside in drugs to treat AML and MDS

(30:50)- Joshua's three wishes for healthcare

(35:13)- Outro

This content has been funded by medac.

• Reducing the rate of lower urinary tract symptoms-related BCG treatment discontinuation;
• How to increase the confidence of urologists regarding BCG side effect management;
• How to make adequate use of the major drug classes used in the management of BCG side effects; and
• When healthcare professionals should make the call to switch treatments.

Are we entering a new era in the fight against antimicrobial resistance (AMR)? Listen to our latest podcast series to hear how sustainable access to effective antibiotics and diagnostic development may impact the battle against AMR.

Are we entering a new era in the fight against antimicrobial resistance (AMR)? Listen to our latest podcast series to hear how sustainable access to effective antibiotics and diagnostic development may impact the battle against AMR.