Empowered Patient Podcast

Dr. Jula Inrig is the Chief Medical Officer of Travere Therapeutics and is eager to find innovative treatments for rare kidney diseases, which can be challenging to diagnose and have limited therapeutic options. In clinical trials, their lead candidate, sparsentan, reduces proteinuria significantly in patients with IgA Nephropathy and focal segmental glomerulosclerosis (FSGS). Travere is working with the U.S. Preventive Task Force to encourage earlier diagnosis and screening for these often silent diseases.

Jula explains, "We've mapped out a path to get therapies approved for trying to avoid really what is one of the most detrimental complications of kidney disease, which is kidney failure, where you essentially wind up on dialysis. This is a treatment option where patients need to go into a clinic and be hooked up to a machine which cleans their blood three times a week. Or the other option is transplantation. One of the things that we have worked on is a molecule called sparsentan to try and avoid kidney failure."

"Sparsentan is an investigational product candidate. It is a single molecule that doesn't suppress the immune system, which I think for a lot of our patients that's very important. It blocks two hormones that are in the path of causing damage within the kidney. What we have found with sparsentan is it reduces the pressure within the kidney, and it causes some remodeling within the kidney that reduces leakage of protein. When you leak protein within your kidney, that causes the kidney to then not clear toxins and then ultimately to progress faster causing kidney failure."

@TravereRare #TravereTherapeutics #RareDiseases #RareKidneyDisease #KidneyDisease #EarlyDiagnosis

Travere.com

Listen to the podcast here

Dr. Jula Inrig is the Chief Medical Officer of Travere Therapeutics and is eager to find innovative treatments for rare kidney diseases, which can be challenging to diagnose and have limited therapeutic options. In clinical trials, their lead candidate, sparsentan, reduces proteinuria significantly in patients with IgA Nephropathy and focal segmental glomerulosclerosis (FSGS). Travere is working with the U.S. Preventive Task Force to encourage earlier diagnosis and screening for these often silent diseases.

Jula explains, "We've mapped out a path to get therapies approved for trying to avoid really what is one of the most detrimental complications of kidney disease, which is kidney failure, where you essentially wind up on dialysis. This is a treatment option where patients need to go into a clinic and be hooked up to a machine which cleans their blood three times a week. Or the other option is transplantation. One of the things that we have worked on is a molecule called sparsentan to try and avoid kidney failure."

"Sparsentan is an investigational product candidate. It is a single molecule that doesn't suppress the immune system, which I think for a lot of our patients that's very important. It blocks two hormones that are in the path of causing damage within the kidney. What we have found with sparsentan is it reduces the pressure within the kidney, and it causes some remodeling within the kidney that reduces leakage of protein. When you leak protein within your kidney, that causes the kidney to then not clear toxins and then ultimately to progress faster causing kidney failure."

@TravereRare #TravereTherapeutics #RareDiseases #RareKidneyDisease #KidneyDisease

Travere.com

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Dr. Lyle Berkowitz, CEO of KeyCare Medical, is listening to consumer feedback and helping health systems provide more virtual care options, particularly for routine types of care. At the same time, KeyCare is working with providers on a strategy that enables them to come up with a plan to care for patients with higher complexity that requires them to be seen in the office. The key to success is the systems integration and data sharing that is possible with this virtual care approach.

Lyle explains, "I think virtualists and virtual care technology need to be different in various ways from traditional office-based care, in a good way. It needs to focus on a more routine set of problems. It needs to be done in a highly efficient manner to be convenient and less expensive while maintaining quality."

"So with KeyCare, we are providing access to a tech-enabled virtual care workforce to health systems, and we're doing it all on Epic. So we have our own instance of Epic that we're staffing with virtualists. We're mainly working with health systems who also have Epic so that they can feel they've got a partner that is able to work cohesively with them."

"In terms of partnering with health systems, the competition is usually third parties who've developed their own proprietary telehealth-focused technology. That, unfortunately, doesn't integrate well with respect to both workflow or data sharing in health systems. That's why we decided to work with Epic because they have a very mature electronic health record system. They now have a mature telehealth system, and they have a level of interoperability between Epic sites that is unseen anywhere else."

#KeyCareMedical #DigitalHealth #VirtualHealthCare #Telehealth #Virtualists #Epic

keycare.org

Listen to the podcast here

Dr. Lyle Berkowitz, CEO of KeyCare Medical, is listening to consumer feedback and helping health systems provide more virtual care options, particularly for routine types of care. At the same time, KeyCare is working with providers on a strategy that enables them to come up with a plan to care for patients with higher complexity that requires them to be seen in the office. The key to success is the systems integration and data sharing that is possible with this virtual care approach.

Lyle explains, "I think virtualists and virtual care technology need to be different in various ways from traditional office-based care, in a good way. It needs to focus on a more routine set of problems. It needs to be done in a highly efficient manner to be convenient and less expensive while maintaining quality."

"So with KeyCare, we are providing access to a tech-enabled virtual care workforce to health systems, and we're doing it all on Epic. So we have our own instance of Epic that we're staffing with virtualists. We're mainly working with health systems who also have Epic so that they can feel they've got a partner that is able to work cohesively with them."

"In terms of partnering with health systems, the competition is usually third parties who've developed their own proprietary telehealth-focused technology. That, unfortunately, doesn't integrate well with respect to both workflow or data sharing in health systems. That's why we decided to work with Epic because they have a very mature electronic health record system. They now have a mature telehealth system, and they have a level of interoperability between Epic sites that is unseen anywhere else."

#KeyCareMedical #DigitalHealth #VirtualHealthCare #Telehealth #Virtualists #Epic

keycare.org

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Dr. Leslie Soiles is the Chief Audiologist at HearingLife, which provides hearing care through professionals who conduct hearing assessments at physical locations and make recommendations for the appropriate way to treat hearing loss. With advancements in nanotechnology and the availability of over-the-counter hearing aids, there are more opportunities to address hearing loss. Still, there are many issues to be aware of when using those devices.

Leslie explains, "Over-the-counter hearing aids are designed for people with mild to moderate hearing loss. Over-the-counter hearing aids don't require a hearing test to be performed, so if somebody thinks that they might be a candidate for OTC, over-the-counter hearing aids, I really do recommend that they first start with that hearing test to make sure that their need falls within the standard of what an over-the-counter hearing aid is designed for."

"In HearingLife, we recommend people start at age 60, and that provides that baseline measurement. As those statistics that I mentioned earlier indicate, going forward from that point, the likelihood of hearing loss is very high. And so, if you can just start monitoring the status of your hearing because it does progress slowly. Having an annual hearing test starting at age 60 gives you that yardstick to measure as you go forward so that you aren't surprised by it."

"For the first time ever, we have patients that have normal hearing, but they love the Bluetooth streaming capability that current hearing aids have. And so, I've had people with normal hearing saying, "Hey, I wish I could wear hearing aids too." That was unheard of before."

@HearingLife #HearingLife #HearingHealth #Audiology #HearingAids #OTCHearingAids

hearinglife.com

Listen to the podcast here

Dr. Leslie Soiles is the Chief Audiologist at HearingLife, which provides hearing care through professionals who conduct hearing assessments at physical locations and make recommendations for the appropriate way to treat hearing loss. With advancements in nanotechnology and the availability of over-the-counter hearing aids, there are more opportunities to address hearing loss. Still, there are many issues to be aware of when using those devices.

Leslie explains, "Over-the-counter hearing aids are designed for people with mild to moderate hearing loss. Over-the-counter hearing aids don't require a hearing test to be performed, so if somebody thinks that they might be a candidate for OTC, over-the-counter hearing aids, I really do recommend that they first start with that hearing test to make sure that their need falls within the standard of what an over-the-counter hearing aid is designed for."

"In HearingLife, we recommend people start at age 60, and that provides that baseline measurement. As those statistics that I mentioned earlier indicate, going forward from that point, the likelihood of hearing loss is very high. And so, if you can just start monitoring the status of your hearing because it does progress slowly. Having an annual hearing test starting at age 60 gives you that yardstick to measure as you go forward so that you aren't surprised by it."

"For the first time ever, we have patients that have normal hearing, but they love the Bluetooth streaming capability that current hearing aids have. And so, I've had people with normal hearing saying, "Hey, I wish I could wear hearing aids too." That was unheard of before."

@HearingLife #HearingLife #HearingHealth #Audiology #HearingAids #OTCHearingAids

hearinglife.com

Download the transcript here

Dr. Sherry McAllister is a practicing chiropractor and President of the Foundation for Chiropractic Progress which recently commissioned a Harris Poll about physical and mental health. One of the most concerning findings was that the link between physical and mental pain was strongest in survey participants 35-44 years old. Geographic location was also a factor, as was the sharp difference in how men and women respond to pain. Treating the mind and the body is essential for good health, and F4CP promotes guidelines that emphasize that non-pharmaceutical options for pain treatment should be the first choice, not the last resort.

Sherry explains, "What we learned was that half of the US adults, just about 44%, actually reported that they had experienced physical pain that they believe was worsened due to mental or emotional pain. We now know there's a link between mental health and physical pain. It's been well-established in the healthcare community. Still, the past two years have really broadened the public's understanding of this association and how managing one condition without treating the other can be counterproductive."

"I think we need to identify and we need to manage all the root causes of conditions that really create havoc in the bone, the nervous system, the muscle, and the mind. And I think when we look back at that Harris Poll, it'll hopefully remind us and inspire healthcare professionals that they can approach every patient holistically to help them achieve their optimal goal. And that's kind of where I sit. If you want to learn more about mental-physical health connections, we have a fantastic book. It's called Depression, Dopamine, and Drug-Free Interventions: How Chiropractic Care Is Supporting Mental Health, and we can share that with you."

@F4CP #ThinkChiropractic #ChiropracticCare #Chiropractor #MentalHealth #PhysicalPain

Find Sherry's podcast, Adjusted Reality, where you get your podcasts

F4CP.org

Listen to the podcast here

Dr. Sherry McAllister is a practicing chiropractor and President of the Foundation for Chiropractic Progress which recently commissioned a Harris Poll about physical and mental health. One of the most concerning findings was that the link between physical and mental pain was strongest in survey participants 35-44 years old. Geographic location was also a factor, as was the sharp difference in how men and women respond to pain. Treating the mind and the body is essential for good health, and F4CP promotes guidelines that emphasize that non-pharmaceutical options for pain treatment should be the first choice, not the last resort.

Sherry explains, "What we learned was that half of the US adults, just about 44%, actually reported that they had experienced physical pain that they believe was worsened due to mental or emotional pain. We now know there's a link between mental health and physical pain. It's been well-established in the healthcare community. Still, the past two years have really broadened the public's understanding of this association and how managing one condition without treating the other can be counterproductive."

"I think we need to identify and we need to manage all the root causes of conditions that really create havoc in the bone, the nervous system, the muscle, and the mind. And I think when we look back at that Harris Poll, it'll hopefully remind us and inspire healthcare professionals that they can approach every patient holistically to help them achieve their optimal goal. And that's kind of where I sit. If you want to learn more about mental-physical health connections, we have a fantastic book. It's called Depression, Dopamine, and Drug-Free Interventions: How Chiropractic Care Is Supporting Mental Health, and we can share that with you."

@F4CP #ThinkChiropractic #ChiropracticCare #Chiropractor #MentalHealth #PhysicalPain

Find Sherry's podcast, Adjusted Reality, where you get your podcasts

F4CP.org

Download the transcript here

Mehdi Maghsoodnia is the CEO of 1health and is determined to bring advanced diagnostic medical tests to a broader audience to enable more patients to benefit from precision medicine advancements. Too often, patients are put on costly drugs that are not effective. Using data from advanced testing allows clinicians to diagnose conditions more accurately and to determine the best treatment approach.

Mehdi elaborates, "Where we focus is really more on how do we make these advanced diagnostic tests cheaper and faster, so we can introduce more accurate, clean data into that care pathway. You want to know very quickly, very accurately, all that you need to know about the specifics of the patient, the specifics of their genetics, and the specifics of the potential tumor type, interaction with drugs, and so on and so forth. Those are the types of information we are trying to deliver into the care decision pathway very quickly."

"That data set is building up very rapidly because we've been sequencing patients, and we've been tracking the impact of the drug on those patients. Now, those databases are coming to the clinical market. They're not there today everywhere, so unfortunately, you might get the best pharmacogenomic results in some of the advanced institutions in urban areas, like San Francisco and New York, but you don't get it everywhere."

"Part of our push on the pharmacogenomic side is to make sure that it's available and accessible by everybody. Health equity is a big issue right now. We are making sure that the test is not only affordable, but it's easy to order, and it's easy to include in the healthcare pathway for every patient at every point in the care system."

@ihealthio #1health #PrecisionMedicine #AdvancedDiagnostics #DiagnosticTesting #CancerDetection #Pharmacogenomic

1health.io

Listen to the podcast here

Mehdi Maghsoodnia is the CEO of 1health and is determined to bring advanced diagnostic medical tests to a broader audience to enable more patients to benefit from precision medicine advancements. Too often, patients are put on costly drugs that are not effective. Using data from advanced testing allows clinicians to diagnose conditions more accurately and to determine the best treatment approach.

Mehdi elaborates, "Where we focus is really more on how do we make these advanced diagnostic tests cheaper and faster, so we can introduce more accurate, clean data into that care pathway. You want to know very quickly, very accurately, all that you need to know about the specifics of the patient, the specifics of their genetics, and the specifics of the potential tumor type, interaction with drugs, and so on and so forth. Those are the types of information we are trying to deliver into the care decision pathway very quickly."

"That data set is building up very rapidly because we've been sequencing patients, and we've been tracking the impact of the drug on those patients. Now, those databases are coming to the clinical market. They're not there today everywhere, so unfortunately, you might get the best pharmacogenomic results in some of the advanced institutions in urban areas, like San Francisco and New York, but you don't get it everywhere."

"Part of our push on the pharmacogenomic side is to make sure that it's available and accessible by everybody. Health equity is a big issue right now. We are making sure that the test is not only affordable, but it's easy to order, and it's easy to include in the healthcare pathway for every patient at every point in the care system."

@ihealthio #1health #PrecisionMedicine #AdvancedDiagnostics #DiagnosticTesting #CancerDetection #Pharmacogenomic

1health.io

Download the transcript here