Empowered Patient Podcast

Dr. Sonja Tarrago, head of Physician Strategy and Engagement at DexCare, has created a care orchestration platform to help health systems improve patient access to care, direct patients to the proper care, and optimize provider capacity. DexCare solutions have enabled health systems to treat more patients with existing resources, increase new patient acquisition, and reduce time to care. This platform reduces long wait times, provides real-time online scheduling, and matches patient demand with provider availability.

Sonja explains, "DexCare is a care orchestration platform used by leading health systems to help manage the supply and demand of healthcare. That means that our platform helps health systems get discovered at the point of search. So, where patients are searching for care, we know that's typically Google, and then we navigate patients to the best fit care. So we do that while optimizing provider capacity and resources in real time. So, as we talk about our customers, we think that first of all, we need to acknowledge that healthcare is in crisis right now."

"In addition to making care more discoverable, we're using data to help direct our patients to the right care based on what they're looking for. This makes sure that the patients are getting connected to the right resources within the health systems that we work with, and we're helping to reduce bottlenecks and improve efficiencies within the health system."

"So we need to help patients find care, not find a doctor. In addition to that, I think another gap is that patients have limited access to real-time online scheduling. And by that, I don't mean a form that a patient fills out and waits for someone to get back to them. I mean a real-time slot that patients can book into."

#DexCare #CareOrchestration #DigitalHealth #CareOptimization

dexcare.com

Download the transcript here

David Norris, Founder and CEO of Affineon Health Inc., recognizes the significant problem of provider burnout, which is primarily caused by the time doctors spend on administrative tasks rather than with the patient. Affineon's AI-powered solution aims to address this by automating the review of the provider's inbox and reducing their cognitive load. The inboxes are filled with lab results, pharmacy messages, and other tasks that need review. This approach enables doctors to focus on the required actions quickly.

David explains, "We're attacking one of the biggest problems providers often complain about: the inbox. And this is their clinical inbox, not their email inbox like you and I have. The clinical inbox is typically filled with hundreds of things that come in daily. For a PCP, this can often include things like lab results. So you go to your doctor for your annual wellness visit, and they order five to 10 different labs, which come into their inbox the next day. If you're seeing 20 patients a day, that's hundreds of results, plus you're getting prescription renewal requests from the pharmacies, you're getting patient messages. The provider, while trying to stay focused on seeing 20 patients a day and keeping their focus on those patients, they're now literally trying to squeeze a little inbox time in before and after patients."

"Affineon has introduced an AI inbox that integrates directly into the electronic health record system. We do exactly what you would do if you hired an assistant in the medical terminology, triage your inbox, which is to handle everything they can handle. The provider focuses on the most critical things. So we're using an AI agent to do that, and unlike a human, which would be very costly to do this, our solution costs $2.50 a day. So about half a cup of coffee. So, for a provider to now have the ability to have an assistant triage their inbox every day and to help them by reducing their daily inbox volume by up to 50%-60%, that's pretty incredible. And before AI, that wasn't possible."

#Affineon #MedAI #ProviderBurnout #AIInbox

affineon.com

Listen to the podcast here

David Norris, Founder and CEO of Affineon Health Inc., recognizes the significant problem of provider burnout, which is primarily caused by the time doctors spend on administrative tasks rather than with the patient. Affineon's AI-powered solution aims to address this by automating the review of the provider's inbox and reducing their cognitive load. The inboxes are filled with lab results, pharmacy messages, and other tasks that need review. This approach enables doctors to focus on the required actions quickly.

David explains, "We're attacking one of the biggest problems providers often complain about: the inbox. And this is their clinical inbox, not their email inbox like you and I have. The clinical inbox is typically filled with hundreds of things that come in daily. For a PCP, this can often include things like lab results. So you go to your doctor for your annual wellness visit, and they order five to 10 different labs, which come into their inbox the next day. If you're seeing 20 patients a day, that's hundreds of results, plus you're getting prescription renewal requests from the pharmacies, you're getting patient messages. The provider, while trying to stay focused on seeing 20 patients a day and keeping their focus on those patients, they're now literally trying to squeeze a little inbox time in before and after patients."

"Affineon has introduced an AI inbox that integrates directly into the electronic health record system. We do exactly what you would do if you hired an assistant in the medical terminology, triage your inbox, which is to handle everything they can handle. The provider focuses on the most critical things. So we're using an AI agent to do that, and unlike a human, which would be very costly to do this, our solution costs $2.50 a day. So about half a cup of coffee. So, for a provider to now have the ability to have an assistant triage their inbox every day and to help them by reducing their daily inbox volume by up to 50%-60%, that's pretty incredible. And before AI, that wasn't possible."

#Affineon #MedAI #ProviderBurnout #AIInbox

affineon.com

Download the transcript here

Dr. Jason Williams, President and Director of Interventional Oncology and Immunotherapy at the Williams Cancer Institute, uses a combination of Pulse Electric Field technology to ablate tumors and direct injection of immunotherapy drugs into the tumor to stimulate the immune system. This approach can be used in conjunction with traditional cancer treatments and has fewer side effects than standard immunotherapy. This method is part of the broader trend in cancer research to provide a more targeted approach to treating tumors.

Jason explains, "Our big focus is going to the tumor itself, so we do treatments directly at the tumor, and we do a combination of things. We do things that will be considered ablation where we're using different technologies or energies — I'll explain — particularly, we use one called Pulse Electric Field (PEF), which kills the tumor by essentially shocking it, and that kills it in a way that actually makes the immune system see it better. You're not trying to kill all of the tumor, you're trying to kill pieces for the immune system. Then we inject drugs into that area of the tumor, particularly immunotherapy drugs, but it can be other drugs as well, and just really taking the fight to the cancer right in the tumor."

"I think that our mistake in cancer treatments is that we're not addressing the tumors directly. I mean, it's one thing to expect that you're going to take a drug orally or intravenously and that it's going to arrive and make it to the cancer cells. Still, the other way is to go right into it, putting the drugs there, and particularly with immunotherapies, where you want to attract the immune system to it. You want those drugs in the cancer, you don't want them just everywhere in the body."

#WilliamsCancer #Cancer #Oncology #Tumors #Immunotherapy #PulseElectricField #ImmuneSystem #TargetingTumors

WilliamsCancerInstitute.com

Listen to the podcast here

Dr. Jason Williams, President and Director of Interventional Oncology and Immunotherapy at the Williams Cancer Institute, uses a combination of Pulse Electric Field technology to ablate tumors and direct injection of immunotherapy drugs into the tumor to stimulate the immune system. This approach can be used in conjunction with traditional cancer treatments and has fewer side effects than standard immunotherapy. This method is part of the broader trend in cancer research to provide a more targeted approach to treating tumors.

Jason explains, "Our big focus is going to the tumor itself, so we do treatments directly at the tumor, and we do a combination of things. We do things that will be considered ablation where we're using different technologies or energies — I'll explain — particularly, we use one called Pulse Electric Field (PEF), which kills the tumor by essentially shocking it, and that kills it in a way that actually makes the immune system see it better. You're not trying to kill all of the tumor, you're trying to kill pieces for the immune system. Then we inject drugs into that area of the tumor, particularly immunotherapy drugs, but it can be other drugs as well, and just really taking the fight to the cancer right in the tumor."

"I think that our mistake in cancer treatments is that we're not addressing the tumors directly. I mean, it's one thing to expect that you're going to take a drug orally or intravenously and that it's going to arrive and make it to the cancer cells. Still, the other way is to go right into it, putting the drugs there, and particularly with immunotherapies, where you want to attract the immune system to it. You want those drugs in the cancer, you don't want them just everywhere in the body."

#WilliamsCancer #Cancer #Oncology #Tumors #Immunotherapy #PulseElectricField #ImmuneSystem #TargetingTumors

WilliamsCancerInstitute.com

Download the transcript here

Joel Stanley is the CEO of Ajna Biosciences, a company developing the next generation of botanical medicines. These full-spectrum drugs, derived from plants and fungi, are regulated and approved through the FDA, unlike dietary supplements. Lead drug candidates are targeting autism, generalized anxiety disorder, and PTSD. With expertise in cultivating and scaling the production of botanical raw materials, Ajna is creating a sustainable model compared to wild-harvested botanicals.

Joel explains, "It's no secret that before about a hundred years ago, all of our medicines were botanical medicines, or mostly coming from plants, or maybe mushrooms. And in the last century, as we developed Western medicine - modern medicine - the drug approval process started to learn how to synthesize molecules and isolate molecules from nature. So we started to step completely away from plant medicine and into a synthetic pharmaceutical landscape. The FDA fairly recently started allowing botanical drugs. So what that means is that it's full-spectrum medicines coming from the given root, shrub, leaf, flower, or mushroom. Those would be botanical drugs. So botanical drugs are not single-compound botanically derived drugs, which make up about 20% of our pharmaceuticals. They're a full-spectrum plant extract, a botanical drug from a regulatory standpoint."

"So, plant-based therapeutics can mean dietary supplements that do not go through clinical trials. They're not legally prescribed by doctors and generally not covered by insurance. Whereas botanical drugs go through the FDA drug approval process, rigorous clinical trials against placebo control to become FDA approved, covered by insurance, and legally prescribable. So that's really what sets what we're doing, creating botanical drugs, apart from what people have considered plant medicine this last century."

"Our most advanced drug in our pipeline is called AJA001, and it's very special to me because I've been basically working on this drug for more than 15 years. It's made in partnership with my previous company. I was the first CEO of a company called Charlotte's Web, which was really the first, and it's still the largest CBD brand out there. It was everything we learned at Charlotte's Web that kind of prompted me to start Ajna BioSciences four years ago. And that first drug is made from full-spectrum hemp, so it is CBD dominant, and it does have other cannabinoids, such as THC, as well as other minor cannabinoids. It also has certain terpenes."

#AjnaBiosciences #BotanicalMedicine #PlantBasedTherapeutics #PharmaInnovation #DrugDevelopment #NaturalMedicine #BioTech

ajnabiosciences.com

Listen to the podcast here

Joel Stanley is the CEO of Ajna Biosciences, a company developing the next generation of botanical medicines. These full-spectrum drugs, derived from plants and fungi, are regulated and approved through the FDA, unlike dietary supplements. Lead drug candidates are targeting autism, generalized anxiety disorder, and PTSD. With expertise in cultivating and scaling the production of botanical raw materials, Ajna is creating a sustainable model compared to wild-harvested botanicals.

Joel explains, "It's no secret that before about a hundred years ago, all of our medicines were botanical medicines, or mostly coming from plants, or maybe mushrooms. And in the last century, as we developed Western medicine - modern medicine - the drug approval process started to learn how to synthesize molecules and isolate molecules from nature. So we started to step completely away from plant medicine and into a synthetic pharmaceutical landscape. The FDA fairly recently started allowing botanical drugs. So what that means is that it's full-spectrum medicines coming from the given root, shrub, leaf, flower, or mushroom. Those would be botanical drugs. So botanical drugs are not single-compound botanically derived drugs, which make up about 20% of our pharmaceuticals. They're a full-spectrum plant extract, a botanical drug from a regulatory standpoint."

"So, plant-based therapeutics can mean dietary supplements that do not go through clinical trials. They're not legally prescribed by doctors and generally not covered by insurance. Whereas botanical drugs go through the FDA drug approval process, rigorous clinical trials against placebo control to become FDA approved, covered by insurance, and legally prescribable. So that's really what sets what we're doing, creating botanical drugs, apart from what people have considered plant medicine this last century."

"Our most advanced drug in our pipeline is called AJA001, and it's very special to me because I've been basically working on this drug for more than 15 years. It's made in partnership with my previous company. I was the first CEO of a company called Charlotte's Web, which was really the first, and it's still the largest CBD brand out there. It was everything we learned at Charlotte's Web that kind of prompted me to start Ajna BioSciences four years ago. And that first drug is made from full-spectrum hemp, so it is CBD dominant, and it does have other cannabinoids, such as THC, as well as other minor cannabinoids. It also has certain terpenes."

#AjnaBiosciences #BotanicalMedicine #PlantBasedTherapeutics #PharmaInnovation #DrugDevelopment #NaturalMedicine #BioTech

ajnabiosciences.com

Download the transcript here

Dana Brown serves as President, CEO, and Chairman of the Board at iCAD Inc., which has developed a next-generation approach that leverages advancements in AI and imaging technology to improve the accuracy and efficiency of breast cancer screening. This technology can help reduce unnecessary biopsies and additional tests while more accurately identifying cancers that need immediate attention. The concerning trend of rising breast cancer in younger women highlights the importance of early detection and personalized care plans.

Dana explains, "Literally, iCAD's first FDA-cleared product in a first-generation AI was around 2002. So it's been well over 20 years. We're now on our fourth generation. So, yes, you're very accurate in describing this as a next-generation approach. So, not only has imaging technology improved over the past 20 years, but artificial intelligence has also improved. We continue to leverage the latest in artificial intelligence technology, how the artificial intelligence can be trained and learn, and a broad base of researchers that help us develop the solution. So you have new minds, new ways to think about solving the problem, and new technology that can be used to solve the problem. Then, there is a new underlying screening technology that gets better and better at clearer imaging."

"The American Cancer Society reports that if we can catch a breast cancer very early in stage one, then the likelihood of, I'll say surviving breast cancer is 99%, so very, very high. So the earlier we can catch a breast cancer, the less invasive and costly and length of time the treatments can be. There are more options for those patients as well as the likelihood of a positive outcome, being able to again, have no further evidence of the disease is increased."

#iCAD #BreastCancer #BreastCancerScreening #Radiology #CancerDetection #BreastBiopsies #Mammogram #WomensHealth #MedAI

icadmed.com

Listen to the podcast here

Dana Brown serves as President, CEO, and Chairman of the Board at iCAD Inc., which has developed a next-generation approach that leverages advancements in AI and imaging technology to improve the accuracy and efficiency of breast cancer screening. This technology can help reduce unnecessary biopsies and additional tests while more accurately identifying cancers that need immediate attention. The concerning trend of rising breast cancer in younger women highlights the importance of early detection and personalized care plans.

Dana explains, "Literally, iCAD's first FDA-cleared product in a first-generation AI was around 2002. So it's been well over 20 years. We're now on our fourth generation. So, yes, you're very accurate in describing this as a next-generation approach. So, not only has imaging technology improved over the past 20 years, but artificial intelligence has also improved. We continue to leverage the latest in artificial intelligence technology, how the artificial intelligence can be trained and learn, and a broad base of researchers that help us develop the solution. So you have new minds, new ways to think about solving the problem, and new technology that can be used to solve the problem. Then, there is a new underlying screening technology that gets better and better at clearer imaging."

"The American Cancer Society reports that if we can catch a breast cancer very early in stage one, then the likelihood of, I'll say surviving breast cancer is 99%, so very, very high. So the earlier we can catch a breast cancer, the less invasive and costly and length of time the treatments can be. There are more options for those patients as well as the likelihood of a positive outcome, being able to again, have no further evidence of the disease is increased."

#iCAD #BreastCancer #BreastCancerScreening #Radiology #CancerDetection #BreastBiopsies #Mammogram #WomensHealth #MedAI

icadmed.com

Download the transcript here

Dr. Rany Aburashed, CEO and Founder of Neurogen Biomarking, is using a blood-based biomarker looking at p-tau 217 to detect early signs of Alzheimer's disease, up to 8-10 years before the onset of clinical symptoms. The company has built an ecosystem to provide patients with a comprehensive health assessment with an at-home blood test, cognitive testing, access to neurologists, and education on lifestyle changes that can support a good quality of life. Their mission is to take a proactive rather than the current reactive approach to diagnosing and slowing the progression of cognitive decline.

Rany explains, "The challenge for us, and this is what I saw from years of clinical practice and hospital management, is that a disease like Alzheimer's operates almost like a green light. Life is okay, you're having minor issues, but for the most part, you're moving along. Then suddenly you notice a sentinel event, which then becomes that red light, and now you have Alzheimer's dementia. And so the issue that is at the core of Alzheimer's is early detection. Is there a way for us to detect things earlier and, in turn, provide patients with an opportunity to take control of their dementia and make the necessary changes in treatments?"

"In the current setting, the way that we do it in the United States and around the world is really reactive and it is too late by the time your mother or father is developing cognitive complaints. It's very easy to ignore the early stages of it because you can function for three to five years without really anything dramatic happening. So suddenly, when that dramatic instance occurs, for example, you leave the stove on, or you get lost driving back to your house, something that's very obviously outside of the normal, that might trigger you to say, "Let's get Mom checked."

"At launch, our focus is on using the biomarker called p-tau 217. This biomarker can be detected now with more technologies in the blood at microscopic levels, and we couldn't do that effectively 10 or 15 years ago. That science has caught up, and the technology has caught up to a point that now, even 8 to 10 years before any significant clinical symptoms occur, we're able to detect if this protein is elevated. Now, if this protein is elevated, depending on the assay that we use, it's about 93%-97% sensitive for potentially developing Alzheimer's long-term. So it's a good protein to use as a triage protein."

#NeurogenBiomarkings #Biomarkers #BloodBiomarkers #Alzheimers #AlzheimersDisease #CognitiveDecline #Dementia #EarlyDetection #Neurologists

NeurogenBiomarking.com

Listen to the podcast here