Empowered Patient Podcast

Sheila Phicil, Founder and CEO of Phicil-itate Change, works with innovators in healthcare to apply new technologies to solutions that incorporate the patients' voice. One goal is to reduce resistance to change, which often stems from the desire to avoid adding more complexity, by listening to patients, physicians, and community organizations. Data analytics and awareness of social determinants of health can provide insights to develop effective and sustainable solutions. Still, the data must be collected and analyzed in a way that preserves the context and individual experience.

Shelia explains, "Well, the simplest way I can put it is helping the helpers and in this case, it's helping people who want to bring forward good innovation in healthcare. To do it well by focusing the work around the patient's lived experience through understanding their stories and their health data. So what I'm aiming to do is to, one, put out great frameworks and strategies around how to do this well and efficiently and effectively. We are building a platform utilizing blockchain and AI to automate some of this work in collecting patient stories and data and generating insights into how to design health tech solutions that meet their needs."

"So all forms of social innovation, where we're trying to solve human problems, should always start with the people who have lived the experience of the problem and understand through their lens what their perspective is. What I often tell people, especially in the healthcare space, is that someone who has a lived experience of having diabetes or lost a loved one to cancer or is dealing with a rare disease, they become the expert. They become the expert in what that looks like for them, how that affects their life, and what they can tolerate in terms of coping or treatment and other things."

#SocialDeterminantsofHealth #SDOH #MedTech #DataAnalytics

Phicil-itateChange.com

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Sheila Phicil, Founder and CEO of Phicil-itate Change, works with innovators in healthcare to apply new technologies to solutions that incorporate the patients' voice. One goal is to reduce resistance to change, which often stems from the desire to avoid adding more complexity, by listening to patients, physicians, and community organizations. Data analytics and awareness of social determinants of health can provide insights to develop effective and sustainable solutions. Still, the data must be collected and analyzed in a way that preserves the context and individual experience.

Shelia explains, "Well, the simplest way I can put it is helping the helpers and in this case, it's helping people who want to bring forward good innovation in healthcare. To do it well by focusing the work around the patient's lived experience through understanding their stories and their health data. So what I'm aiming to do is to, one, put out great frameworks and strategies around how to do this well and efficiently and effectively. We are building a platform utilizing blockchain and AI to automate some of this work in collecting patient stories and data and generating insights into how to design health tech solutions that meet their needs."

"So all forms of social innovation, where we're trying to solve human problems, should always start with the people who have lived the experience of the problem and understand through their lens what their perspective is. What I often tell people, especially in the healthcare space, is that someone who has a lived experience of having diabetes or lost a loved one to cancer or is dealing with a rare disease, they become the expert. They become the expert in what that looks like for them, how that affects their life, and what they can tolerate in terms of coping or treatment and other things."

#SocialDeterminantsofHealth #SDOH #MedTech #DataAnalytics

Phicil-itateChange.com

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Lisa Ricciardi, CEO, and Dr. Tony Caggiano, Chief Medical Officer at Cognition Therapeutics, are developing effective treatments for neurological disorders, particularly Alzheimer's disease and dementia with Lewy bodies (DLB). While DLB is related to Parkinson's, sharing symptoms include hallucinations, sleep disorders, and cognitive dysfunction, there are no good diagnostics to identify DLB and effective treatments. Cognition Therapeutics' lead drug candidate, an oral treatment, has shown promise in protecting neurons from the toxic effects of the pathological proteins involved in Alzheimer's and DLB.

Lisa explains, "This company started in 2007, so we've had a long number of years to burnish our mission. One of the things we say is we're the beginning of the end of neurologic disorders and the start of hope for an improved future for patients. So Alzheimer's disease, in particular, has been long studied with little success, and in the last few years, we've seen some successes with monoclonal antibodies. There are a number of other approaches in clinical trials, but we have recently generated very positive data in two different trials with an oral once-a-day drug."

Tony elaborates, "Lewy body dementia or dementia with Lewy bodies is a disease very much related to Parkinson's disease that's believed to be, in part, caused by pathological levels of a certain protein called alpha synuclein and particularly small oligomers of misfolded alpha synuclein."

"And in Alzheimer's disease, this is largely a cognitive memory disorder as it presents. So, those two diseases are very different. Now, the idea of treating them with a single drug is somewhat unique to what we have here at Cognition Therapeutics. So our company started around the idea of developing therapies for Alzheimer's disease, and our lead molecule CT1812 or zervimesine was developed out of a screening assay where we were looking for molecules that could protect neurons or brain cells from the toxicities of this pathological amyloid protein. So, we identified CT1812 and have been developing it."

#CognitionTherapeutics #BrainHealth #DementiaCare #LewyStrong #Livingwithlewy #Alzheimers #EndAlz #Alzheimersdisease #DLBAwareness #NeurodegenerativeDisease #Dementia #DementiaWithLewyBodies

cogrx.com

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Lisa Ricciardi, CEO, and Dr. Tony Caggiano, Chief Medical Officer at Cognition Therapeutics, are developing effective treatments for neurological disorders, particularly Alzheimer's disease and dementia with Lewy bodies (DLB). While DLB is related to Parkinson's, sharing symptoms include hallucinations, sleep disorders, and cognitive dysfunction, there are no good diagnostics to identify DLB and effective treatments. Cognition Therapeutics' lead drug candidate, an oral treatment, has shown promise in protecting neurons from the toxic effects of the pathological proteins involved in Alzheimer's and DLB.

Lisa explains, "This company started in 2007, so we've had a long number of years to burnish our mission. One of the things we say is we're the beginning of the end of neurologic disorders and the start of hope for an improved future for patients. So Alzheimer's disease, in particular, has been long studied with little success, and in the last few years, we've seen some successes with monoclonal antibodies. There are a number of other approaches in clinical trials, but we have recently generated very positive data in two different trials with an oral once-a-day drug."

Tony elaborates, "Lewy body dementia or dementia with Lewy bodies is a disease very much related to Parkinson's disease that's believed to be, in part, caused by pathological levels of a certain protein called alpha synuclein and particularly small oligomers of misfolded alpha synuclein."

"And in Alzheimer's disease, this is largely a cognitive memory disorder as it presents. So, those two diseases are very different. Now, the idea of treating them with a single drug is somewhat unique to what we have here at Cognition Therapeutics. So our company started around the idea of developing therapies for Alzheimer's disease, and our lead molecule CT1812 or zervimesine was developed out of a screening assay where we were looking for molecules that could protect neurons or brain cells from the toxicities of this pathological amyloid protein. So, we identified CT1812 and have been developing it."

#CognitionTherapeutics #BrainHealth #DementiaCare #LewyStrong #Livingwithlewy #Alzheimers #EndAlz #Alzheimersdisease #DLBAwareness #NeurodegenerativeDisease #Dementia #DementiaWithLewyBodies

cogrx.com

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Arielle Smith, the President of Life Science at Event Cadence, discusses the changes in the event technology landscape and the expectations of pharmaceutical companies and attendees for a hybrid approach, including participation in person and virtually. There is an increased demand for insight capturing and analytics to measure the return on investment in conferences and the time attendees spend there. The platform includes scheduling, appointment management, and lead generation with tools to encourage networking and interaction to enhance the event experience.

Arielle explains, "Medical conferences are held all over the world, as you know, and there's not always going to be a time where you can physically put boots on the ground and travel for them. So we're seeing a lot more of a hot tier point, a hybrid model approach to it where, let's say, the majority of the team will be in a meeting room face to face with some of their HCPs, but then even that HCP might decide to dial in their counterpart. Or if a pharmaceutical client is not able to participate in person for many different reasons, we're looping them in from a virtual perspective as well. And our platform can help coordinate all of that."

"So there's a lot of talk in the industry about insight capturing and gathering and exactly how that can be done but how best to make it actionable. Many great platforms are spinning up recently that are meant for capturing recordings or recording a conversation like the one you and I are having now, but then using AI to transcribe it all. A lot of our accounts are playing with technology like that, and then our platform is being used to set those conversations up."

#EventCadence #MedicalConferences #ConferenceManagement #HybridConferences

eventcadence.com

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Arielle Smith, the President of Life Science at Event Cadence, discusses the changes in the event technology landscape and the expectations of pharmaceutical companies and attendees for a hybrid approach, including participation in person and virtually. There is an increased demand for insight capturing and analytics to measure the return on investment in conferences and the time attendees spend there. The platform includes scheduling, appointment management, and lead generation with tools to encourage networking and interaction to enhance the event experience.

Arielle explains, "Medical conferences are held all over the world, as you know, and there's not always going to be a time where you can physically put boots on the ground and travel for them. So we're seeing a lot more of a hot tier point, a hybrid model approach to it where, let's say, the majority of the team will be in a meeting room face to face with some of their HCPs, but then even that HCP might decide to dial in their counterpart. Or if a pharmaceutical client is not able to participate in person for many different reasons, we're looping them in from a virtual perspective as well. And our platform can help coordinate all of that."

"So there's a lot of talk in the industry about insight capturing and gathering and exactly how that can be done but how best to make it actionable. Many great platforms are spinning up recently that are meant for capturing recordings or recording a conversation like the one you and I are having now, but then using AI to transcribe it all. A lot of our accounts are playing with technology like that, and then our platform is being used to set those conversations up."

#EventCadence #MedicalConferences #ConferenceManagement #HybridConferences

eventcadence.com

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Dr. Thomas Chen, Founder, CEO, and CSO of NeOnc Technologies, is working on the challenge of delivering drugs across the blood-brain barrier by using an intranasal delivery approach to target brain cancers. This delivery platform leverages the cranial nerve to transport the drugs directly to the brain, bypassing the blood-brain barrier. Genomic analysis of the long-surviving patients in the phase one trial revealed a common genetic mutation, informing the trial design for the next phase.

Thomas explains, "So our platform is what we call intranasal delivery. And with the intranasal delivery, we're not trying to cross the blood-brain barrier. We're trying to cross over it. And how we're doing that is doing the delivery of the drug via what we call the C nerves. Now the cranial nerves are, we have 12 cranial nerves in our brain. These cranial nerves have various functions, but the cranial nerves involved with the nasal brain delivery are the first and the fifth cranial nerves. The first cranial nerve is what we call the olfactory nerve. That's the nerve that's responsible for smell. The fifth cranial nerve is called the trigeminal nerve, which involves facial sensation and allows us to chew."

"So what happens is that when we want to deliver the drug to the brain cancer, we have the patient inhale it. When the patient inhales, it goes through the nose, and through the olfactory nerve, it goes to the brain. Usually, that molecule then absorbs in the spinal brain and then circulates to the target, in this case, brain cancer. Now you know how powerful that cranial nerve is from the standpoint of what it does when you smell something, that scent, that odor gets transported from the olfactory nerve to our brain. And that's basically what we're doing. We're taking something external to the brain, allowing the cranial nerve to absorb and transport it to the brain."

#NeOnc #BloodBrainBarrier #BBB #BrainCancer #DrugDelivery

neonc.com

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Dr. Thomas Chen, Founder, CEO, and CSO of NeOnc Technologies, is working on the challenge of delivering drugs across the blood-brain barrier by using an intranasal delivery approach to target brain cancers. This delivery platform leverages the cranial nerve to transport the drugs directly to the brain, bypassing the blood-brain barrier. Genomic analysis of the long-surviving patients in the phase one trial revealed a common genetic mutation, informing the trial design for the next phase.

Thomas explains, "So our platform is what we call intranasal delivery. And with the intranasal delivery, we're not trying to cross the blood-brain barrier. We're trying to cross over it. And how we're doing that is doing the delivery of the drug via what we call the C nerves. Now the cranial nerves are, we have 12 cranial nerves in our brain. These cranial nerves have various functions, but the cranial nerves involved with the nasal brain delivery are the first and the fifth cranial nerves. The first cranial nerve is what we call the olfactory nerve. That's the nerve that's responsible for smell. The fifth cranial nerve is called the trigeminal nerve, which involves facial sensation and allows us to chew."

"So what happens is that when we want to deliver the drug to the brain cancer, we have the patient inhale it. When the patient inhales, it goes through the nose, and through the olfactory nerve, it goes to the brain. Usually, that molecule then absorbs in the spinal brain and then circulates to the target, in this case, brain cancer. Now you know how powerful that cranial nerve is from the standpoint of what it does when you smell something, that scent, that odor gets transported from the olfactory nerve to our brain. And that's basically what we're doing. We're taking something external to the brain, allowing the cranial nerve to absorb and transport it to the brain."

#NeOnc #BloodBrainBarrier #BBB #BrainCancer #DrugDelivery

neonc.com

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Ali Morin, Chief Nursing Informatics Officer at symplr, emphasizes the need to focus on the challenges nurses face and AI's potential to reduce administrative burdens and nurse burnout. Significant staffing shortages, scheduling challenges, and increased patient acuity demand better data analytics and technology implementation to allow nurses to spend more time with patients and improve patient care. For successful integration of technology solutions into the nurses' workflow, pilot tests, training of new and experienced nurses, and listening to their concerns and ideas are essential.

Ali explains, "We focus on the nursing informatics side -- that middle communicator between technology and the nurses at the bedside. So, I consider myself a translator. I listen to the clinicians and the nurses who are using our software, and we have a number of solutions that are applicable for direct care nurses as well as nurse managers and nurse leaders. I take in the pain points that they're experiencing today and bring them to our developers and our product teams. This allows them to understand the pain points that nurses are experiencing and how we can help solve some of those problems."

"However, we're taking it to the next level and putting in some additional machine learning around which nurses are still available to pick up shifts and which nurses are still available who haven't maybe met their core component. Today, how that's done: there are spreadsheets, call lists, and post-it notes all over the place. Who have I called? Who have I checked with? Who hasn't seen this manual kind of back-and-forth? And so our work is really to make that balancing phase of the nursing scheduling simpler, pun intended, 100%, but also simpler so that we can make it so those nurses and nurse managers, the nurses can say, I want to work these kinds of shifts. The nurse managers can say, great, plug them in, and off they go. And then it's less time in that kind of back and forth between them."

#symplr #Nurses #HealthTech #HealthcareAI #CompassSurvey

symplr.com

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Ali Morin, Chief Nursing Informatics Officer at symplr, emphasizes the need to focus on the challenges nurses face and AI's potential to reduce administrative burdens and nurse burnout. Significant staffing shortages, scheduling challenges, and increased patient acuity demand better data analytics and technology implementation to allow nurses to spend more time with patients and improve patient care. For successful integration of technology solutions into the nurses' workflow, pilot tests, training of new and experienced nurses, and listening to their concerns and ideas are essential.

Ali explains, "We focus on the nursing informatics side -- that middle communicator between technology and the nurses at the bedside. So, I consider myself a translator. I listen to the clinicians and the nurses who are using our software, and we have a number of solutions that are applicable for direct care nurses as well as nurse managers and nurse leaders. I take in the pain points that they're experiencing today and bring them to our developers and our product teams. This allows them to understand the pain points that nurses are experiencing and how we can help solve some of those problems."

"However, we're taking it to the next level and putting in some additional machine learning around which nurses are still available to pick up shifts and which nurses are still available who haven't maybe met their core component. Today, how that's done: there are spreadsheets, call lists, and post-it notes all over the place. Who have I called? Who have I checked with? Who hasn't seen this manual kind of back-and-forth? And so our work is really to make that balancing phase of the nursing scheduling simpler, pun intended, 100%, but also simpler so that we can make it so those nurses and nurse managers, the nurses can say, I want to work these kinds of shifts. The nurse managers can say, great, plug them in, and off they go. And then it's less time in that kind of back and forth between them."

#symplr #Nurses #HealthTech #HealthcareAI #CompassSurvey

symplr.com

Download the transcript here