Sidharth speaks with Dr. Maksim Mamonkin (Ph.D), an Assistant Professor of Medicine at the Baylor College of Medicine studying the immunobiology of CAR T-cells for the treatment of T cell lymphomas and leukemias. Dr. Mamonkin's team has developed fratricide resistant CAR T-cells for T cell malignancies, and he's currently translating his findings to the clinic via several ongoing Phase I clinical trials. Our conversation begins by discussing autologous CAR T-cell methods and problems with cell fratricide. Then, we shift to discussing allogeneic CAR T-cells and the bioengineering challenges that lie in the future for CAR T-cell therapy.

Learn more by vising my website: https://www.brooklynmusings.com/.

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Sidharth sits down with Dr. Hans-Willem Snoeck (M.D., Ph.D.,), a Professor of Medicine at Columbia University studying blood stem cells and the immune system. Dr. Snoeck also focuses on human lung development and disease, and he's made groundbreaking discoveries in growing lung cells from stem cells. Our conversation spanned many areas: we discussed lung development, stem cell therapies, and Dr. Snoeck's beginnings in science.

Learn more by reading this episode's notes: https://www.brooklynmusings.com/post/from-a-cell-to-a-lung-an-arduous-journey

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