Reset Recharge

Ep 03: Breaking Down the WHI Hormone Therapy Trials


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Ever since the first Women’s Health Initiative (WHI) findings were announced in 2002, women have been led to believe that hormone replacement therapy (HRT) is unsafe. The premature halt of estrogen-progestin therapy due to safety concerns resulted in a significant decline in HRT use, leaving many women to needlessly abandon a treatment that offered symptomatic relief from severe menopausal symptoms.

In today's episode, we're diving deep into the WHI hormone therapy trials. We'll explore the key questions the trials aimed to answer, delve into the study's design, and dissect the findings from both the estrogen and progesterone arm and the estrogen-only arm. Additionally, we'll examine the conclusions drawn from the study, recent revisions to those conclusions, and emphasize the urgent need for further research in this area of women's health. 

Join me as we unravel the complexities of the WHI study and uncover the truths behind hormone replacement therapy.

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Reset RechargeBy Komal Patil-Sisodia, MD

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