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19. Is Weed a Psychedelic? Exploring Cannabis’s Trippy Side
Can weed make you trip like acid or mushrooms? In this week’s episode of The High Guide, April Pride unpacks the surprisingly psychedelic effects of cannabis—especially in potent doses. From the science of THC and the default mode network to the mysterious powers of new cannabinoids like THCP, this episode offers a fresh look at how weed can shift your sense of self, time, and the world around you. Plus, hear what happens when you mix cannabis with classic psychedelics like LSD or psilocybin—and why some folks swear it’s euphoric while others spiral into anxiety. If you’ve ever wondered whether weed is a psychedelic or how crossfading really works, this episode delivers clarity, curiosity, and caution.
🔵 Key Takeaways
-THC impacts the same brain receptors as classic psychedelics—just with shorter, subtler effects.
-High doses of potent weed can suppress the default mode network, producing psychedelic-like shifts in perception.
-Combining cannabis with LSD or mushrooms intensifies the trip for some, while others report increased anxiety.
-THCP is a new, hyper-potent cannabinoid that may explain wildly different high experiences.
-Mixing psychedelics should be done mindfully—especially for newer users.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/is-cannabis-a-psychedelic
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset
By April Pride5
1818 ratings
19. Is Weed a Psychedelic? Exploring Cannabis’s Trippy Side
Can weed make you trip like acid or mushrooms? In this week’s episode of The High Guide, April Pride unpacks the surprisingly psychedelic effects of cannabis—especially in potent doses. From the science of THC and the default mode network to the mysterious powers of new cannabinoids like THCP, this episode offers a fresh look at how weed can shift your sense of self, time, and the world around you. Plus, hear what happens when you mix cannabis with classic psychedelics like LSD or psilocybin—and why some folks swear it’s euphoric while others spiral into anxiety. If you’ve ever wondered whether weed is a psychedelic or how crossfading really works, this episode delivers clarity, curiosity, and caution.
🔵 Key Takeaways
-THC impacts the same brain receptors as classic psychedelics—just with shorter, subtler effects.
-High doses of potent weed can suppress the default mode network, producing psychedelic-like shifts in perception.
-Combining cannabis with LSD or mushrooms intensifies the trip for some, while others report increased anxiety.
-THCP is a new, hyper-potent cannabinoid that may explain wildly different high experiences.
-Mixing psychedelics should be done mindfully—especially for newer users.
Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/is-cannabis-a-psychedelic
Hosted by April Pride
Sign up for April’s newsletter on Substack at https://aprilpride.substack.com/ or at getsetset.com
Follow on IG: @getsetset / YouTube: youtube.com/@getsetset / X: @getsetset

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