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In this episode of Reset Recharge, Dr. Komal Patil-Sisodia explores a groundbreaking study that reveals how menopause hormone therapy (MHT) may actually reduce the risk of type 2 diabetes in perimenopausal women with prediabetes.

Dr. Komal unpacks the data from a major Diabetes and Metabolism study of over 6,500 women aged 46–60, showing that those who used hormone therapy were 30% less likely to develop diabetes. She explains the science behind how estrogen supports metabolic health — improving insulin sensitivity, lowering inflammation, reducing central fat gain, and supporting pancreatic function — and why timing, age, BMI, and ethnicity make all the difference.

You’ll learn:

• How estrogen affects blood sugar and fat distribution
• Why MHT works best when started near menopause
• Which hormone formulations and delivery routes are safest and most effective
• Why personalized, evidence-based care is key to menopause medicine

Whether you’re navigating perimenopause, supporting patients, or simply curious about hormone health, this episode breaks down complex science into practical takeaways you can use.

💡 Key takeaway: Menopause hormone therapy isn’t just about symptom relief — it can be metabolic protection for the right woman, at the right time.

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Time Stamps:

00:00 – 00:54 | Welcome & Episode Overview  
00:55 – 02:30 | The Study That Sparked the Conversation  
02:31 – 04:00 | Who Benefits Most from Hormone Therapy  
04:01 – 06:00 | How Estrogen Supports Metabolic Health  
06:01 – 07:45 | The Timing Hypothesis Explained  
07:46 – 09:15 | Type & Route of Hormone Therapy Matter  
09:16 – 10:45 | Balancing Benefits and Risks  
10:46 – 12:15 | The Takeaway: Personalized Menopause Care  
12:16 – 13:06 | Closing & Next Steps

References:

Shih YH, Yang CY, Wang SJ, Lung CC. Menopausal hormone therapy decreases the likelihood of diabetes development in peri‑menopausal individuals with prediabetes. Diabetes Metab. 2024 Jul;50(4):101546. doi: 10.1016/j.diabet.2024.101546. Epub 2024 Jun 5. PMID: 38843591.

Thanks for listening. Find more info about Reset Recharge on the website or Instagram.