After the Bengals week off, the team is fully rested and ready to take on another tough challenge in the San Francisco 49ers (Opponents in Super Bowls XVI and XXIII). The Bengals' 3 wins so far this season have all come against NFC West opponents, a win over the 49ers would be a sweep of the division. San Francisco ("San Fran" as only Zac Taylor calls it) is frustrated and angry after 2 straight road losses. We'll discuss all the injury news, matchups to watch, and what this game means for both teams.

Listen Now for a comprehensive preview of a blockbuster matchup!